Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells

Circulation

Volumn 104, Issue 1, 2001, Pages 79-84

  Lavigne, Mark C ^a   Malech, Harry L ^a   Holland, Steven M ^a   Leto, Thomas L ^a,b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Muscle; NADPH oxidase; P47phox; Smooth; Superoxide; Transduction

Indexed keywords

ANGIOTENSIN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; ENZYME SUBSTRATE COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

EID: 0035800101     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.104.1.79     Document Type: Article

References (35)

1. Signal transduction by reactive oxygen species in non-phagocytic cells
2. Role of angiotensin and oxidative stress in essential hypertension
3. Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
4. The respiratory burst oxidase
5. Specific labeling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamide adenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium
6. Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs
7. Diphenylene iodonium as an inhibitor of the NADPH oxidase complex of bovine neutrophils: Factors controlling the inhibitory potency of diphenylene iodonium in a cell-free system of oxidase activation
8. An NADPH oxidase superoxide-generating system in the rabbit aorta
9. Expression of phagocyte NADPH oxidase components in human endothelial cells
10. Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
11. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
12. Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells
13. Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin: Evidence that p47phox may participate in forming this oxidase in vitro and in vivo
14. Expression of NADH/NADPH oxidase p22phox in human coronary arteries
15. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
16. The p47phox mouse knock-out model of chronic granulomatous disease
17. A monoclonal antibody against a-smooth muscle actin: A new probe for smooth muscle differentiation
18. Functional reconstitution of the phagocyte NADPH oxidase by transfection of its multiple components in a heterologous system
19. 2 for platelet-derived growth factor signal transduction
20. Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-κB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells
21. Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease
22. Regulation of differentiation of vascular smooth muscle cells
23. Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: Studies with cells from normals and patients with chronic granulomatous disease
24. NAD(P)H oxidase: Role in cardiovascular biology and disease
25. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
26. Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension
27. The pathogenesis of atherosclerosis: A perspective for the 1990s
28. Protection from reoxygenation injury by inhibition of racl
29. Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22.000
30. Cell transformation by the superoxide-generating Moxl
31. Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure
32. Antioxidant enzymes and human diseases
33. Vascular effects following homozygous disruption of p47phox: An essential component of NADPH oxidase
34. Superoxide anion is an endothelium-derived contracting factor
35. The role of reactive oxygen species in atherosclerosis