Simultaneous determination of ropivacaine and antipyrine by high performance liquid chromatography and its application to the in vitro transplacental study

Biomedical Chromatography

Volumn 18, Issue 9, 2004, Pages 752-755

  Zuo, Ming ^a   Duan, Geng Li ^a   Ge, Zhen Gong ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Antipyrine; Placental transfer; Ropivacaine

Indexed keywords

POTASSIUM COMPOUNDS;

ANTIPYRINE; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; IN-VITRO; ITS APPLICATIONS; ODS COLUMNS; PLACENTAL TRANSFER; ROPIVACAINE; RP-HPLC METHOD; SIMPLE++; SIMULTANEOUS DETERMINATIONS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACETONITRILE; PHENAZONE; PHOSPHORIC ACID; POTASSIUM DIHYDROGEN PHOSPHATE; ROPIVACAINE;

ACCURACY; ARTICLE; CONTROLLED STUDY; COTYLEDON; DRUG CLEARANCE; DRUG DETERMINATION; DRUG TISSUE LEVEL; DRUG TRANSPORT; EXPERIMENTAL MODEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIQUID LIQUID EXTRACTION; PH; PLACENTA PERFUSION; PLACENTAL TRANSFER; RADIATION DETECTION; RELIABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

EID: 9944221953     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.402     Document Type: Article

References (3)

1. Heikkine T, Fkblad U and Laine K. Transplacental transfer of citalopram, fluoxetine and their primary demethylated metabolites in isolated perfused human placenta. International Journal of Obstetrics and Gynaecology 2002; 109: 1003-1008.
2. Johnson RF, Cahana A, Olenick M, Herman N, Paschall RL, Minzter B, Ramasubramanian R, Gonzalez H and Downing JW. A comparison of the placenta] transfer of ropivacaine versus bupivacaine. Anesthesia and Analgesia 1999; 89: 703-708.
3. Schneider H, Panigel M and Dancis J. Transfer across the perfused human placenta of antipyrine, sodium and leucine. American Journal of Obstetrics and Gynaecology 1972; 114: 822-828.