Neuromodulatory drugs in a radical pelvic surgery patient

Journal of Sexual Medicine

Volumn 3, Issue SUPPL. 2, 2006, Pages 77-79

  Mulhall, John P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ERYTHROPOIETIN; IMMUNOPHILIN; MITOGEN ACTIVATED PROTEIN KINASE; NEUROMODULIN; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; PROTEIN C FOS; PROTEIN C JUN; SILDENAFIL; SODIUM CHLORIDE; TACROLIMUS; TADALAFIL;

ARTICLE; CLINICAL TRIAL; COCULTURE; CORPUS CAVERNOSUM; ERECTILE DYSFUNCTION; EXPERIMENTAL MODEL; HUMAN; MALE; NERVE GROWTH; NERVE INJURY; NERVE REGENERATION; NERVE STIMULATION; NERVE SURGERY; NEURITE; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PENILE BLOOD VESSEL; PENIS ERECTION; PRIORITY JOURNAL; PROSTATECTOMY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; SURGICAL ANATOMY; SURGICAL TECHNIQUE; TREATMENT OUTCOME;

EID: 33646062274     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2006.00189.x     Document Type: Article

References (17)

1. Walsh, PC, Marschke, P, Catalona, WJ, Lepor, H, Martin, S, Myers, RP and Steiner, MS. Efficacy of first-generation Cavermap to verify location and function of cavernous nerves during radical prostatectomy: A multi-institutional evaluation by experienced surgeons. Urology 2001; 57: 491-94.
2. Rabbani, F, Stapleton, AMF, Kattan, MW, et al. Factors predicting recovery of erections after radical prostatectomy. J Urol 2000; 164: 1929-34.
3. Stanford, JL, Feng, Z, Hamilton, AS, et al. Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer. The prostate cancer outcomes study. JAMA 2000; 283: 354-60.
4. Talcott, JA, Rieker, P, Clark, JA, et al. Patient-reported symptoms after primary therapy for early prostate cancer: Results of a prospective cohort study. J Clin Oncol 1998; 16: 275-83.
5. Leandri, P, Rossignol, G, Gautier, JR, et al. Radical retropubic prostatectomy: Morbidity and quality of life. experience with 620 consecutive cases. J Urol 1992; 147: 883-87.
6. Catalona, WJ, Carvalhal, GF, Mager, DE, et al. Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol 1999; 162: 433-38.
7. Jonler, M, Messing, EM, Rhodes, PR, et al. Sequelae of radical prostatectomy. Br J Urol 1994; 74: 352-58.
8. Mulhall, JP, Slovick, R, Hotaling, J, Aviv, N, Valenzuela, R, Waters, WB and Flanigan, RC. Erectile dysfunction after radical prostatectomy: Hemodynamic profiles and their correlation with the recovery of erectile function. J Urol 2002; 167: 1371-5.
9. Mulhall, JP and Graydon, RJ. The hemodynamics of erectile dysfunction following nerve-sparing radical retropubic prostatectomy. Int J Impot Res 1996; 8: 91-4.
10. Carrier, S, Zvara, P, Nunes, L, Kour, NW, Rehman, J and Lue, TF. Regeneration of nitric oxide synthase-containing nerves after cavernous nerve neurotomy in the rat. J Urol 1995; 153: 1722-7.
11. User, HM, Hairston, JH, Zelner, DJ, McKenna, KE and McVary, KT. Penile weight and cell subtype specific changes in a post-radical prostatectomy model of erectile dysfunction. J Urol 2003; 169: 1175-9.
12. Leungwattanakij, S, Bivalacqua, TJ, Usta, MF, Yang, DY, Hyun, JS, Champion, HC, Abdel-Mageed, AB and Hellstrom, WJ. Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum. J Androl 2003; 24: 239-45.
13. Snyder SH, SD, Lai MM, Steiner JP, Hamilton GS and Suzdak PD. Neural actions of immunophilin ligands. Trends Pharmacol Sci 1998; 19: 21-6.
14. Sezen, SF, Hoke, A, Burnett, AL and Snyder, SH. Immunophilin ligand FK506 is neuroprotective for penile innervation. Nat Med 2001; 7: 1073-75.
15. Sezen, SF, Blackshaw, S, Steiner, JP and Burnett, AL. FK506 binding protein 12 is expressed in rat penile innervation and upregulated after cavernous nerve injury. Int J Impot Res 2002; 14: 506-11.
16. Musicki, B, Champion, HC, Becker, RE, Liu, T, Kramer, MF and Burnett, AL. Erection capability is potentiated by long-term sildenafil treatment: Role of blood flow-induced endothelial nitric-oxide synthase phosphorylation. Mol Pharmacol 2005; 68: 226-32.
17. Zhang, R, Wang, Y, Zhang, L, Zhang, Z, Tsang, W, Lu, M and Chopp, M. Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 2002; 33: 2675-80.