Acetate generation in rat liver mitochondria; acetyl-CoA hydrolase activity is demonstrated by 3-ketoacyl-CoA thiolase

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1761, Issue 1, 2006, Pages 17-23

  Yamashita, Hiromi ^a   Itsuki, Ai ^a   Kimoto, Masumi ^a   Hiemori, Miki ^a   Tsuji, Hideaki ^a  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

oxidation of fatty acid; 3 ketoacyl CoA thiolase; Acetate metabolism; Acetyl CoA hydrolase; Peroxisome proliferator; Rat liver mitochondria

Indexed keywords

ACETIC ACID; ACETYL COENZYME A ACYLTRANSFERASE; ACETYL COENZYME A HYDROLASE; MITOCHONDRIAL ENZYME; PEROXISOME PROLIFERATOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID OXIDATION; HYDROLYSIS; KINETICS; LIVER MITOCHONDRION; MALE; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; RAT; SEQUENCE ANALYSIS;

ACETATES; ACETYL-COA C-ACYLTRANSFERASE; ACETYL-COA HYDROLASE; ACYL COENZYME A; ANIMALS; CHROMATOGRAPHY, GEL; DIETHYLHEXYL PHTHALATE; ENZYME ACTIVATION; KINETICS; MALE; MITOCHONDRIA, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 33646061646     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2006.01.001     Document Type: Article

References (36)

1. Lindeneg O., Mellemgaard K., Fabricius J., and Lundquist F. Myocardial utilization of acetate, lactate and free fatty acids after ingestion of ethanol. Clin. Sci. 27 (1964) 427-435
2. Lundquist F., Sestoft L., Damgaard S.E., Clausen J.P., and Trap-Jensen J. Utilization of acetate in the human forearm during exercise after ethanol ingestion. J. Clin. Invest. 52 (1973) 3231-3235
3. Jorfeldt L., and Juhlin-Dannfelt A. The influence of ethanol on splanchnic and skeletal muscle metabolism in man. Metabolism 27 (1978) 97-106
4. Skutches C.L., Holroyde C.P., Myers R.N., Paul P., and Reichard G.A. Plasma acetate turnover and oxidation. J. Clin. Invest. 64 (1979) 708-713
5. Skutches C.L., Sigler M.H., Teehan B.P., Cooper J.H., and Reichard G.A. Contribution of dialysate acetate to energy metabolism: metabolic implications. Kidney Int. 23 (1983) 57-63
6. Vinay P., Cardoso M., Tejedor A., Prud'homme M., Levelilleem M., Vinet B., Courteau M., Gougoux A., Rengel M., Lapierre L., and Piette Y. Acetate metabolism during hemodialysis:metabolic considerations. Am. J. Nephrol. 7 (1987) 337-354
7. Frayn K.N., Coppack S.W., Walsh P.E., Butterworth H.C., Humphreys S.M., and Pedrosa H.C. Metabolic responses of forearm and adipose tissues to acute ethanol ingestion. Metabolism 39 (1990) 958-966
8. Putman C.T., Spriet L.L., Hultman E., Dyck D.J., and Heigenhauser G.J.F. Skeletal muscle pyruvate dehydrogenase activity during acetate infusion in humans. Am. J. Physiol.: Endocrinol. Metab. 268 31 (1995) E1007-E1017
9. Suokas A., Forsander O., and Lindros K. Distribution and utilization of alcohol-derived acetate in the rat. J. Stud. Alcohol 45 (1984) 381-385
10. Annison E.F., and Armstrong D.G. Volatile fatty acid metabolism and energy supply. In: Phillipson A.T. (Ed). Physiology of Digestion and Metabolism in the Ruminant (1970), Oriel, Newcastle 422-437
11. Ballard F.J. Supply and utilization of acetate in mammals. Am. J. Clin. Nutr. 25 (1972) 773-779
12. Knowles S.E., Jarrett I.G., Filsell O.H., and Ballard F.J. Production and utilization of acetate in mammals. Biochem. J. 142 (1974) 401-411
13. Seufert C.D., Graf M., Janson G., Kuhn A., and Soling H.D. Formation of free acetate by isolated perfused livers from normal, starved and diabetic rats. Biochem. Biophys. Res. Commun. 57 (1974) 901-909
14. Yamashita H., Kaneyuki T., and Tagawa K. Production of acetate in the liver and its utilization in peripheral tissues. Biochim. Biophys. Acta 1532 (2001) 79-87
15. Bernson S.M. Acetyl-CoA hydrolase: activity, regulation and physiological significance of the enzyme in brown adipose tissue from hamster. Eur. J. Biochem. 67 (1976) 403-410
16. Alexson S.E.H., and Nedergaard J. A novel type of short- and medium chain acyl-CoA hydrolases in brown adipose tissue mitochondria. J.Biol.Chem. 263 (1988) 13564-13571
17. Alexson S.E.H., Svensson L.T., and Nedergaard J. NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat. Biochim. Biophys. Acta 1005 (1989) 13-19
18. Osmundsen H., Neat C.E., and Borrebaek B. Fatty acid products of peroxisomal β-oxidation. Int. J. Biochem. 12 (1980) 625-630
19. Alexson S.E.H., Osmundsen H., and Berge R.K. The presence of acyl-CoA hydrolase in rat brown-adipose-tissue peroxisomes. Biochem. J. 262 (1989) 41-46
20. Hovik R., Brodal B., Bartlett K., and Osmundsen H. Metabolism of acetyl-CoA by isolated peroxisomal fractions: formation of acetate and acetoacetyl-CoA. J. Lipid Res. 32 (1991) 993-999
21. Wilcke M., and Alexson S.E.H. Characterization of acyl-CoA thioesterase activity in isolated rat liver peroxisomes. Partial purification and characterization of a long-chain acyl-coA thioesterase. Eur. J. Biochem. 222 (1994) 803-811
22. Grigat K.P., Koppe K., Seufert C.D., and Soling H.D. Acetyl-coenzyme A deacylase activity in liver is not an artifact. Subcellular distribution and substrate specificity of acetyl-coenzyme A deacylase activities in rat liver. Biochem, J. 177 (1979) 71-79
23. Robinson J.J., Mahan D.E., and Koeppe R.E. Studies on rat brain acyl-coenzyme A hydrolase (short chain). Biochem. Biophys. Res. Commun. 71 (1976) 959-965
24. Prass R.L., Isohashi F., and Utter M.F. Purification and characterization of an extramitochondrial acetyl coenzyme A hydrolase from rat liver. J. Biol.Chem. 255 (1980) 5215-5223
25. Lee F.-J.S., Lin L.-W., and Smith J.A. Purification and characterization of an acetyl-CoA hydrolase from Saccharomyces cerevisiae. Eur. J. Biochem. 184 (1989) 21-28
26. Svensson L.T., Kilpelainen S.H., Hiltunen J.K., and Alexson S.E.H. Characterization and isolation of enzymes that hydrolyze short-chain acyl-CoA in rat-liver mitochondria. Eur. J. Biochem. 239 (1996) 526-531
27. Fleisher S., McIntyre J.O., and Vidal J.C. Large-scale preparation of rat liver mitochondria in high yield. Methods Enzymol. 55 (1979) 32-39
28. Miyazawa S., Osumi T., and Hashimoto T. The presence of a new 3-oxoacyl-CoA thiolase in rat liver peroxisomes. Eur. J. Biochem. 103 (1980) 589-596
29. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
30. Laemmli U.K. Cleavage of structure proteins during assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
31. Fukao T., Kamijo K., Osumi T., Fujiki Y., Yamaguchi S., Orii T., and Hashimoto T. Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat mitochondrial acetoacetyl-CoA thiolase. J. Biochem. 106 (1989) 197-204
32. Bernson V.S.M., and Nicholls D.G. Acetate, a major end product of fatty acid oxidation in hamster brown-adipose-tissue mitochondria. Eur. J. Biochem. 47 (1974) 517-525
33. Gergely J., Hele P., and Ramakrishnan C.V. Succinyl and acetyl coenzyme A deacylases. J. Biol. Chem. 198 (1952) 323-334
34. Miyazawa S., Furuta S., Osumi T., Hashimoto T., and Ui N. Properties of peroxisomal 3-ketoacyl-CoA thiolase from rat liver. J. Biochem. 90 (1981) 511-519
35. Siess E.A., Brocks D.G., Lattke H.K., and Wieland O.H. Effect of glucagon on metabolite compartmentation in isolated rat liver cells during gluconeogenesis from lactate. Biochem. J. 166 (1977) 225-235
36. Gilbert H.F., Lennox B.J., Mossman C.D., and Carle W.C. The relation of acyl transfer to the overall reaction of thiolase I from porcine heart. J. Biol. Chem. 256 (1981) 7371-7377