Vγ1 γδ T cells regulate type-1/type-2 immune responses and participate in the resistance to infection and development of heart inflammation in Trypanosoma cruzi-infected BALB/c mice

Microbes and Infection

Volumn 8, Issue 3, 2006, Pages 880-888

  Nomizo, Auro ^a   Cardillo, Fabíola ^b   Postól, Edilberto ^a   de Carvalho, Lain Pontes ^b   Mengel, José ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

T cells; CD40L; IFN ; IL 4; Susceptibility; Trypanosoma cruzi

Indexed keywords

CD40 LIGAND; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEART; IMMUNE RESPONSE; IN VIVO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; INFLAMMATORY INFILTRATE; INNATE IMMUNITY; MEMORY T LYMPHOCYTE; MOUSE; MOUSE STRAIN; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SPLEEN; T LYMPHOCYTE; TH1 CELL; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

ANIMALS; ANTIBODIES, MONOCLONAL; CD40 LIGAND; CHAGAS DISEASE; HEART DISEASES; INFLAMMATION; INTERFERON TYPE II; MICE; MICE, INBRED BALB C; MICE, NUDE; MUSCLE, SKELETAL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SPLEEN; T-LYMPHOCYTE SUBSETS; UP-REGULATION;

ANIMALIA; TRYPANOSOMA CRUZI;

EID: 33646031829     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2005.10.012     Document Type: Article

References (38)

1. Silva J.S., Morrissey P.J., Grabstein K.H., Mohler K.M., Anderson D., and Reed S.G. Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection. J. Exp. Med. 175 (1992) 169
2. Cardillo F., Voltarelli J.C., Reed S.G., and Silva J.S. Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells. Infect. Immun. 64 (1996) 128
3. Cardillo F., Cunha F.Q., Tamashiro W.M., Russo M., Garcia S.B., and Mengel J. NK1.1+ cells and T-cell activation in euthymic and thymectomized C57Bl/6 mice during acute Trypanosoma cruzi infection. Scand. J. Immunol. 55 (2002) 96
4. Godfrey D.I., MacDonald H.R., Kronenberg M., Smyth M.J., and Van Kaer L. NKT cells: what's in a name?. Nat. Rev. Immunol. 4 (2004) 231
5. Lees R.K., Ferrero I., and MacDonald H.R. Tissue-specific segregation of TCRgamma delta+ NKT cells according to phenotype TCR repertoire and activation status: parallels with TCR alphabeta+NKT cells. Eur. J. Immunol. 31 (2001) 2901
6. Chien Y.H., and Hampl J. Antigen-recognition properties of murine gamma delta T cells. Springer Semin. Immunopathol. 22 (2000) 239
7. Azuara V., Grigoriadou K., Lembezat M.P., Nagler-Anderson C., and Pereira P. Strain-specific TCR repertoire selection of IL-4-producing Thy-1 dull gamma delta thymocytes. Eur. J. Immunol. 31 (2001) 205
8. Azuara V., Levraud J.P., Lembezat M.P., and Pereira P. A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire. Eur. J. Immunol. 27 (1997) 544
9. Azuara V., Lembezat M.P., and Pereira P. The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gammadelta T cell population is due to cellular selection. Eur. J. Immunol. 28 (1998) 3456
10. Azuara V., and Pereira P. Genetic mapping of two murine loci that influence the development of IL-4-producing Thy-1dull gamma delta thymocytes. J. Immunol. 165 (2000) 42
11. Cardillo F., Falcao R.P., Rossi M.A., and Mengel J. An age-related gamma delta T cell suppressor activity correlates with the outcome of autoimmunity in experimental Trypanosoma cruzi infection. Eur. J. Immunol. 23 (1993) 2597
12. Cardillo F., Nomizo A., and Mengel J. The role of the thymus in modulating gammadelta T cell suppressor activity during experimental Trypanosoma cruzi infection. Int. Immunol. 10 (1998) 107
13. Huber S.A., Graveline D., Newell M.K., Born W.K., and O'Brien R.L. V gamma 1+ T cells suppress and V gamma 4+ T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice. J. Immunol. 165 (2000) 4174
14. O'Brien R.L., Yin X., Huber S.A., Ikuta K., and Born W.K. Depletion of a gamma delta T cell subset can increase host resistance to a bacterial infection. J. Immunol. 165 (2000) 6472
15. Szczepanik M., Anderson L.R., Ushio H., Ptak W., Owen M.J., Hayday A.C., and Askenase P.W. Gamma/delta T cells from tolerized alpha/beta-TCR-deficient mice antigen specifically inhibit contact sensitivity in vivo and IFN-gamma production in vitro. Int. Arch. Allergy Immunol. 113 (1997) 373
16. Szczepanik M., Anderson L.R., Ushio H., Ptak W., Owen M.J., Hayday A.C., and Askenase P.W. Gamma delta T cells from tolerized alpha beta T cell receptor (TCR)-deficient mice inhibit contact sensitivity-effector T cells in vivo, and their interferon-gamma production in vitro. J. Exp. Med. 184 (1996) 2129
17. Mengel J., Cardillo F., Aroeira L.S., Williams O., Russo M., and Vaz N.M. Anti-gamma delta T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice. Immunol. Lett. 48 (1995) 97
18. Ladel C.H., Blum C., and Kaufmann S.H. Control of natural killer cell-mediated innate resistance against the intracellular pathogen Listeria monocytogenes by gamma/delta T lymphocytes. Infect. Immun. 64 (1996) 1744
19. O'Brien R.L., Lahn M., Born W.K., and Huber S.A. T cell receptor and function cosegregate in gamma-delta T cell subsets. Chem. Immunol. 79 (2001) 1
20. Michailowsky V., Silva N.M., Rocha C.D., Vieira L.Q., Lannes-Vieira J., and Gazzinelli R.T. Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection. Am. J. Pathol. 159 (2001) 1723
21. Hiyama K., Hamano S., Nakamura T., Nomoto K., and Tada I. IL-4 reduces resistance of mice to Trypanosoma cruzi infection. Parasitol. Res. 87 (2001) 269
22. Chaussabel D., Jacobs F., de Jonge J., de Veerman M., Carlier Y., Thielemans K., Goldman M., and Vray B. CD40 ligation prevents Trypanosoma cruzi infection through interleukin-12 upregulation. Infect. Immun. 67 (1999) 1929
23. Leslie D.S., Vincent M.S., Spada F.M., Das H., Sugita M., Morita C.T., and Brenner M.B. CD1-mediated gamma/delta T cell maturation of dendritic cells. J. Exp. Med. 196 (2002) 1575
24. Quezada S.A., Jarvinen L.Z., Lind E.F., and Noelle R.J. CD40/CD154 Interactions at the interface of tolerance and immunity. Annu. Rev. Immunol. 22 (2004) 307
25. Bourgeois C., Rocha B., and Tanchot C. A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory. Science 297 (2002) 2060
26. Ferrick D.A., Braun R.K., Lepper H.D., and Schrenzel M.D. Gamma delta T cells in bacterial infections. Res. Immunol. 147 (1996) 532
27. Fujihashi K., Kiyono H., Aicher W.K., Green D.R., Singh B., Eldridge J.H., and McGhee J.R. Immunoregulatory function of CD3+, CD4-, and CD8- T cells. Gamma delta T cell receptor-positive T cells from nude mice abrogate oral tolerance. J. Immunol. 143 (1989) 3415
28. Fujihashi K., Taguchi T., McGhee J.R., Eldridge J.H., Bruce M.G., Green D.R., Singh B., and Kiyono H. 1990. Regulatory function for murine intraepithelial lymphocytes. Two subsets of CD3+, T cell receptor-1+ intraepithelial lymphocyte T cells abrogate oral tolerance. J. Immunol. 145 (1990) 2010
29. Fujihashi K., Taguchi T., Aicher W.K., McGhee J.R., Bluestone J.A., Eldridge J.H., and Kiyono H. Immunoregulatory functions for murine intraepithelial lymphocytes: gamma/delta T cell receptor-positive (TCR+) T cells abrogate oral tolerance, while alpha/beta TCR+ T cells provide B cell help. J. Exp. Med. 175 (1992) 695
30. Fujihashi K., Yamamoto M., McGhee J.R., and Kiyono H. Function of alpha beta TCR+ and gamma delta TCR+ IELs for the gastrointestinal immune response. Int. Rev. Immunol. 11 (1994) 1
31. Fujihashi K., Kawabata S., Hiroi T., Yamamoto M., McGhee J.R., Nishikawa S., and Kiyono H. Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 3613
32. Fujihashi K., McGhee J.R., Kweon M.N., Cooper M.D., Tonegawa S., Takahashi I., Hiroi T., Mestecky J., and Kiyono H. gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses. J. Exp. Med. 183 (1996) 1929
33. Fujihashi K., McGhee J.R., Yamamoto M., Hiroi T., and Kiyono H. Role of gamma delta T cells in the regulation of mucosal IgA response and oral tolerance. Ann. N.Y. Acad. Sci. 778 (1996) 55
34. Hayday A., and Tigelaar R. Immunoregulation in the tissues by gammadelta T cells. Nat. Rev. Immunol. 3 (2003) 233
35. Bradley L.M. Migration and T-lymphocyte effector function. Curr. Opin. Immunol. 15 (2003) 343
36. Dalton J.E., Pearson J., Scott P., and Carding S.R. The interaction of gamma delta T cells with activated macrophages is a property of the V gamma 1 subset. J. Immunol. 171 (2003) 6488
37. Dalton J.E., Howell G., Pearson J., Scott P., and Carding S.R. Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells. J. Immunol. 173 (2004) 3660
38. Cardillo F., Nomizo A., Postol E., and Mengel J. NK1.1 cells are required to control T cell hyperactivity during Trypanosoma cruzi infection. Med. Sci. Monit. 10 8 (2004) 259