Single breath N2-test and exhaled nitric oxide in men

Respiratory Medicine

Volumn 100, Issue 6, 2006, Pages 1013-1019

  Olin, Anna Carin ^a   Andelid, Kristina ^a   Vikgren, Jenny ^a   Rosengren, Annika ^a   Larsson, Sven ^a   Bake, Björn ^a   Ekberg Jansson, Ann ^a  

^a St Sigfridsg 85   (Sweden)

Author keywords

Exhaled air; N2 test; Nitric oxide; Small airways

Indexed keywords

NITRIC OXIDE; NITROGEN; STEROID; GLUCOCORTICOID;

ANALYZER; ARTICLE; ASTHMA; CHEMOLUMINESCENCE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; EARLY DIAGNOSIS; EXHALATION; FOLLOW UP; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; LINEAR REGRESSION ANALYSIS; LUNG VENTILATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOM SAMPLE; RESPIRATORY TRACT INFLAMMATION; SINGLE BREATH NITROGEN TEST; SPIROMETRY; SYMPTOMATOLOGY; AGED; BREATH ANALYSIS; CASE CONTROL STUDY; COMPUTER ASSISTED TOMOGRAPHY; INFLAMMATION; LUNG; LUNG GAS EXCHANGE; METABOLISM; PATHOPHYSIOLOGY; RADIOGRAPHY; SMOKING; STATISTICAL MODEL;

AGED; BREATH TESTS; CASE-CONTROL STUDIES; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HUMANS; INFLAMMATION; LINEAR MODELS; LUNG; MALE; NITRIC OXIDE; NITROGEN; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY GAS EXCHANGE; SMOKING; SPIROMETRY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33646029958     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2005.09.037     Document Type: Article

References (36)

1. Leuppi J.D., Salome C.M., Jenkins C.R., Anderson S.D., Xuan W., Marks G.B., et al. Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids. Am J Respir Crit Care Med 163 2 (2001) 406-412
2. Jones S.L., Kittelson J., Cowan J.O., Flannery E.M., Hancox R.J., McLachlan C.R., et al. The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. Am J Respir Crit Care Med 164 5 (2001) 738-743
3. Sterk P.J., De Gouw H.W., Ricciardolo F.L., and Rabe K.F. Exhaled nitric oxide in COPD: glancing through a smoke screen. Thorax 54 7 (1999) 565-567
4. Persson M.G., Zetterstrom O., Agrenius V., Ihre E., and Gustafsson L.E. Single-breath nitric oxide measurements in asthmatic patients and smokers. Lancet 343 8890 (1994) 146-147
5. Kharitonov S.A., Robbins R.A., Yates D., Keatings V., and Barnes P.J. Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am J Respir Crit Care Med 152 2 (1995) 609-612
6. Clini E., Bianchi L., Pagani M., and Ambrosino N. Endogenous nitric oxide in patients with stable COPD: correlates with severity of disease. Thorax 53 10 (1998) 881-883
7. Ichinose M., Sugiura H., Yamagata S., Koarai A., and Shirato K. Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways. Am J Respir Crit Care Med 162 2 Part 1 (2000) 701-706
8. Loppow D., Schleiss M.B., Kanniess F., Taube C., Jorres R.A., and Magnussen H. In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation. Respir Med 95 2 (2001) 115-121
9. Maziak W., Loukides S., Culpitt S., Sullivan P., Kharitonov S.A., and Barnes P.J. Exhaled nitric oxide in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 157 3 Part 1 (1998) 998-1002
10. Agusti A.G., Villaverde J.M., Togores B., and Bosch M. Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary disease. Eur Respir J 14 3 (1999) 523-528
11. Silkoff P.E., Martin D., Pak J., Westcott J.Y., and Martin R.J. Exhaled nitric oxide correlated with induced sputum findings in COPD. Chest 119 4 (2001) 1049-1055
12. Chambers D.C., Tunnicliffe W.S., and Ayres J.G. Acute inhalation of cigarette smoke increases lower respiratory tract nitric oxide concentrations. Thorax 53 8 (1998) 677-679
13. Robbins R.A., Millatmal T., Lassi K., Rennard S., and Daughton D. Smoking cessation is associated with an increase in exhaled nitric oxide. Chest 112 2 (1997) 313-318
14. Su Y., Han W., Giraldo C., De Li Y., and Block E.R. Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 19 5 (1998) 819-825
15. Hoyt J.C., Robbins R.A., Habib M., Springall D.R., Buttery L.D., Polak J.M., et al. Cigarette smoke decreases inducible nitric oxide synthase in lung epithelial cells. Exp Lung Res 29 1 (2003) 17-28
16. Fowler W. Lung function studies. III. Uneven pulmonary ventilation in normal subjects and in patients with pulmonary disease. J Appl Physiol 2 (1949) 283-299
17. Anthonisen N.R., Danson J., Roberson P.C., and Ross W.R.D. Airways closure as a function of age. Resp Physiol 8 (1969) 56-65
18. Anthonisen N.R., Robertson P.C., and Ross W. Gravity-dependent sequential emptying of lung regions. J Appl Physiol 28 (1970) 589-595
19. 2 test identify the smoker who will develop chronic airflow limitation?. Am Rev Respir Dis 137 2 (1988) 293-301
20. Buist A.S., and Ross B.B. Predicted values for closing volumes using a modified single breath nitrogen test. Am Rev Respir Dis 107 5 (1973) 744-752
21. Petty T.L., Silvers G.W., Stanford R.E., Baird M.D., and Mitchell R.S. Small airway pathology is related to increased closing capacity and abnormal slope of phase III in excised human lungs. Am Rev Respir Dis 121 3 (1980) 449-456
22. 1. The study of men born in 1913 and 1923. Eur J Respir Dis 69 1 (1986) 46-56
23. Stanescu D., Sanna A., Veriter C., and Robert A. Identification of smokers susceptible to development of chronic airflow limitation: a 13-year follow-up. Chest 114 2 (1998) 416-425
24. Rosengren A., Orth-Gomer K., Wedel H., and Wilhelmsen L. Stressful life events, social support, and mortality in men born in 1933. Br Med J 307 6912 (1993) 1102-1105
25. Tylen U., Boijsen M., Ekberg-Jansson A., Bake B., and Lofdahl C.G. Emphysematous lesions and lung function in healthy smokers 60 years of age. Respir Med 94 1 (2000) 38-43
26. L(CO) and to emphysematous changes on high resolution CT. Respir Med 95 5 (2001) 363-373
27. Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 160 6 (1999) 2104-2117
28. Quanjer P.H., Tammeling G.J., Cotes J.E., Pedersen O.F., Peslin R., and Yernault J.C. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 16 (1993) 5-40
29. Oxhoj H., and Bake B. Measurement of closing volume with the single breath nitrogen method. Scand J Respir Dis 55 6 (1974) 320-331
30. Berglund E., Birath G., Bjure J., Grimby G., Kjellmer I., Sandqvist L., et al. Spirometric studies in normal subjects. I. Forced expirograms in subjects between 7 and 70 years of age. Acta Med Scand 173 (1963) 185-192
31. Salorinne Y. Single-breath pulmonary diffusing capacity. Reference values and application in connective tissue diseases and in various lung diseases. Scand J Respir Dis Suppl 96 (1976) 1-84
32. 2-test and spirometry in healthy non-smoking males. Eur J Respir Dis 65 4 (1984) 296-304
33. Vikgren J., Bake B., Ekberg-Jansson A., Larsson S., and Tylen U. Value of air trapping in detection of small airways disease in smokers. Acta Radiol 44 5 (2003) 517-524
34. Ekberg-Jansson A., Bake B., Andersson B., Skoogh B.E., and Lofdahl C.G. Respiratory symptoms relate to physiological changes and inflammatory markers reflecting central but not peripheral airways. A study in 60-year-old 'healthy' smokers and never-smokers. Respir Med 95 1 (2001) 40-47
35. Pauwels R.A., Buist A.S., Ma P., Jenkins C.R., and Hurd S.S. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. Respir Care 46 8 (2001) 798-825
36. Battaglia S., den Hertog H., Timmers M.C., Lazeroms S.P.G., Vignola A.M., Rabe K.F., et al. Small airways function and molecular markers in exhaled air in mild asthma. Thorax 60 (2005) 639-644