Synthesis and receptor binding studies of 3-substituted piperazine derivatives

European Journal of Medicinal Chemistry

Volumn 41, Issue 3, 2006, Pages 387-396

  Bedürftig, Stephan ^a   Wünsch, Bernhard ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Receptor ligands; 1,2 Anellated piperazines; 3 Substituted piperazines; Aziridinium ions

Indexed keywords

ETHYL 2 (1,4,8 TRIAZOBICYCLO[4.3.0]NONAN 4 YL)ACETATE; ETHYL 2 (4 BENZYL 6 CYANO 1,4 DIAZEPAN 1 YL)ACETATE; ETHYL 2 (6 AZIDO 4 BENZYL 1,4 DIAZEPAN 1 YL)ACETATE; ETHYL 2 (9 OXO 1,4 DIAZABICYCLO[4.3.0]NONAN 4 YL)ACETATE; ETHYL 2 [1 BENZYL 4 (ETHOXYCARBOMETHYL)PIPERAZIN 2 YL]ACETATE; ETHYL 2 [3 (AMINOMETHYL) 4 BENZYLPIPERAZIN 1 YL]ACETATE; ETHYL 2 [3 (AMINOMETHYL)PIPERAZIN 1 YL]ACETATE; ETHYL 2 [3 (AZIDOMETHYL) 4 BENZYLPIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 2 (CYANOMETHYL)PIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 3 (CHLOROMETHYL)PIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 3 (CYANOMETHYL)PIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 3 (METHYLAMINOMETHYL)PIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 3 [N [2 (3,4 DICHLOROPHENYL)ACETYL] N METHYLAMINOMETHYL]PIPERAZIN 1 YL]ACETATE; ETHYL 2 [4 BENZYL 3 [N [2 (3,4 DICHLOROPHENYL)ACETYL]AMINOMETHYL]PIPERAZIN 1 YL]ACETATE; ETHYL 2 [8 [2 (3,4 DICHLOROPHENYL)ACETYL] 1,4,8 TRIAZOBICYCLO[4.3.0]NONAN 4 YL]ACETATE; PIPERAZINE DERIVATIVE; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG; LIGAND; OPIATE RECEPTOR; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HYDROGENATION; NONHUMAN; POLYMERIZATION; RAT; SUBSTITUTION REACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; DRUG SCREENING; GUINEA PIG; METABOLISM; SYNTHESIS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; GUINEA PIGS; LIGANDS; MOLECULAR STRUCTURE; PIPERAZINES; RECEPTORS, OPIOID; RECEPTORS, SIGMA;

EID: 33646009184     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.09.004     Document Type: Article

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