Heterologous complementation of the Klaac null mutation of Kluyveromyces lactis by the Saccharomyces cerevisiae AAC3 gene encoding the ADP/ATP carrier

FEMS Yeast Research

Volumn 6, Issue 3, 2006, Pages 414-420

  Fontanesi, Flavia ^a   Viola, Anna Maria ^a   Ferrero, Iliana ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

ADP ATP carrier; Anaerobiosis; Heterologous complementation; Kluyveromyces lactis; ScAAC3; Semi anaerobiosis

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; OXYGEN;

AAC1 GENE; AAC2 GENE; AAC3 GENE; ARTICLE; FUNGAL GENE; FUNGUS GROWTH; GENE EXPRESSION; GENE MUTATION; GENETIC COMPLEMENTATION; KLAAC GENE; KLUYVEROMYCES; NONHUMAN; PHENOTYPE; SACCHAROMYCES CEREVISIAE;

ANAEROBIOSIS; BLOTTING, NORTHERN; CYTOCHROMES; FERMENTATION; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENETIC COMPLEMENTATION TEST; KLUYVEROMYCES; MITOCHONDRIAL ADP, ATP TRANSLOCASES; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTRUM ANALYSIS; TRANSCRIPTION, GENETIC; TRANSFORMATION, GENETIC;

FUNGI; KLUYVEROMYCES; KLUYVEROMYCES LACTIS; SACCHAROMYCES CEREVISIAE;

EID: 33645990010     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2005.00011.x     Document Type: Article

References (31)

1. Ausubel FM Brent R Kingston RE Moore DD Seidman JG Smith JA Struhl K 1994 Current Protocols in Molecular Biology Wiley New York, NY
2. Betina S Gavurniková G Haviernik P Sabová L Kolarov J 1995 Expression of the AAC2 gene encoding the major mitochondrial ADP/ATP carrier in Saccharomyces cerevisiae is controlled at transcriptional level by oxygen, heme and HAP2 factor J Biochem 229 651 657
3. Bianchi MM Falcone C Chen XJ Wesolowski-Louvel M Frontali L Fukuhara H 1987 Transformation of the yeast Kluyveromyces lactis by new vectors derived from the 1.6-μm circular plasmid pkd1 Curr Genet 12 185 192
4. Bulder CJEA 1964 Lethality of the petite mutation in petite-negative yeasts Antonie Van Leeuwenhoek 30 442 454
5. Chen XJ Fukuhara H 1988 A gene fusion system using the aminoglycoside 3′-phosphotransferase gene of kanamycin-resistance transposon Tn903 use in the yeasts Kluyveromyces lactis and Saccharomyces cerevisiae Gene 69 181 192
6. Clark-Walker GD Chen XJ 2001 Dual mutations reveal interactions between components of oxidative phosphorylation in Kluyveromyces lactis Genetics 159 929 938
7. Couzin N Trezeguet V Le Saux A Lauquin GJ 1996 Cloning of the gene encoding the mitochondrial adenine nucleotide carrier of Schizosaccharomyces pombe by functional complementation in Saccharomyces cerevisiae Gene 171 113 117
8. Drgon T Sabová L Gavurniková G Kolarov J 1992 Yeast ADP/ATP carrier proteins exhibit similar enzymatic properties but their deletion produces different phenotypes FEBS Lett 304 277 280
9. Dujon B Sherman D Fischer G et al 2004 Genome evolution in yeasts Nature 430 35 44
10. Entian KD Barnett JA 1983 Some genetical and biochemical attempts to elucidate the energetics of sugar uptake and explain the Kluyver effect in the yeast Kluyveromyces lactis Curr Genet 7 323 325
11. Ferrero I Viola AM Goffeau A 1981 Induction by glucose of an antimycin-insensitive, azide-sensitive respiration in the yeast Kluyveromyces lactis Antonie van Leeuwenhoek 47 11 24
12. Gavurniková G Sabová L Kissová I Haviernik P Kolarov J 1996 Transcription of the AAC1 gene encoding an isoform of mitochondrial ADP/ATP carrier in Saccharomyces cerevisiae is regulated by oxygen in a heme-independent manner J Biochem 239 759 763
13. Giraud S Bonod-Bidaud C Wesolowski-Louvel M Stepien G 1998 Expression of human ANT2 gene in highly proliferative cells gRBOX, a new transcriptional element, is involved in the regulation of glycolytic ATP import into mitochondria J Mol Biol 281 409 418
14. Goffrini P Algeri AA Donnini C Wesolowski-Louvel M Ferrero I 1989 RAG1 and RAG2 nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars Yeast 5 99 106
15. Goffrini P Ferrero I Donnini C 2002 Respiration-dependent utilization of sugars in yeasts a determinant role for sugar transporters J Bacteriol 184 427 432
16. Klingenberg M 1979 The ADP, ATP shuttle of the mitochondrion Trends in Biochem Sci 4 249 252
17. Kolarov J Kolarová N Nelson N 1990 A third ADP/ATP translocator gene in yeast J Biol Chem 265 12711 12716
18. Kovácová V Irmlerová J Kovác L 1968 Oxidative phosphorylation in yeast. IV. Combination of a nuclear mutation affecting oxidative phosphorylation with a cytoplasmic mutation to respiratory deficiency Biochim Biophys Acta 162 157 162
19. Lawson JE Douglas MG 1988 Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae J Biol Chem 263 14812 14818
20. Levy SE Yu-Sheng C Graham BH Wallace DC 2000 Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes Gene 254 57 66
21. Mentel M Piškur J Neuveglise C Rycovska A Cellengová G Kolarov J 2005 Triplicate genes for mitochondrial ADP/ATP carriers in the aerobic yeast Yarrowia lipolytica are regulated differentially in the absence of oxygen Mol Genet Genomics 273 94 91
22. Nebohacová M Mentel M Nosek J Kolarov J 1999 Isolation and expression of the gene encoding mitochondrial ADP/ATP carrier (AAC) from the pathogenic yeast Candida parapsilosis Yeast 15 1237 1242
23. O'Malley K Pratt P Robertson J Lilly M Douglas MG 1982 Selection of the nuclear gene for the mitochondrial adenine nucleotide translocator by genetic complementation of the op1 mutation in yeast J Biol Chem 257 2097 2103
24. Prior C Mamessier P Fukuhara H Chen XJ Wesolowski-Louvel M 1993 The hexokinase gene is required for transcriptional regulation of glucose transporter gene RAG1 in Kluyveromyces lactis Mol Cell Biol 13 3882 3889
25. Sabová L Zeman I Supek F Kolarov J 1993 Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor Eur J Biochem 213 547 553
26. Saliola M Bartoccioni PC De Maria I Lodi T Falcone C 2004 The deletion of succinate dehydrogenase gene klsdh1 in Kluyveromyces lactis does not lead to respiratory deficiency Eukaryotic Cell 3 589 597
27. Sherman F Fink GR Hicks JB 1983 Methods in Yeast Genetics: a Laboratory Manual Cold Spring Harbor Laboratory Press Cold Spring Harbor, New York
28. Sokoliková B Sabová L Kissová I Kolarov J 2000 A carbon-source-responsive element is required for regulation of the hypoxic ADP/ATP carrier (AAC3) isoform in Saccharomyces cerevisiae Biochem J 352 893 898
29. Trezeguet V Zeman I David C Lauquin GJ Kolarov J 1999 Expression of the ADP/ATP carrier encoding genes in aerobic yeasts; phenotype of an ADP/ATP carrier deletion mutant of Schizosaccharomyces pombe Biochim Biophys Acta 1410 229 236
30. Viola AM Galeotti C Goffrini P Ficarelli A Ferrero I 1995 A Kluyveromyces lactis gene homologous to AAC2 complements the Saccharomyces cerevisiae op1 mutation Curr Genet 27 229 233
31. Viola AM Lodi T Ferrero I 1999 A Klaac null mutant of Kluyveromyces lactis is complemented by a single copy of the Saccharomyces cerevisiae AAC1 gene Curr Genet 36 29 36