Transcription of the AAC1 gene encoding an isoform of mitochondrial ADP/ATP carrier in Saccharomyces cerevisiae is regulated by oxygen in a heme-independent manner

European Journal of Biochemistry

Volumn 239, Issue 3, 1996, Pages 759-763

  Gavurníková, Gabriela ^a   Šabova, Ludmila ^b   Kiššová, Ingrid ^a   Haviernik, Peter ^a   Kolarov, Jordan ^a,b  

^a Physics and Informatics   (Slovakia)

^b CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

ADP ATP carrier; Anaerobiosis; Heme; Saccharomyces cerevisiae

Indexed keywords

CARRIER PROTEIN; MESSENGER RNA; OXYGEN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; GENE MAPPING; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

SACCHAROMYCES CEREVISIAE;

EID: 0030003402     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0759u.x     Document Type: Article

References (19)

1. Adrian, G. S., McCaummon, M. T., Montgomery, D. L. & Douglas, M. G. (1986) Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial membrane, Mol. Cell. Biol. 6, 626-634.
2. Lawson, J. E. & Douglas, M. G. (1988) Separates genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. J. Biol. Chem. 263, 14812-14818.
3. Kovác̀, L., Lachowicz, T. M. & Slonimski, P. (1967) Biochemical genetics of oxidalive phosphorylation, Science 158, 1564-1567.
4. 1, Biochim. Biophys. Acta 267, 465-478.
5. Gawaz, M., Douglas, M. G. & Klingenberg, M. (1990) Structure-function studies of adenine nucleotide transport in mitochondria II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast, J. Biol. Chem. 265, 14202-14208.
6. Liao, X., Small, W. C. Srere, P. A. & Butow, R. A. (1991) Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Sacharomyces cerevisiae. Mol. Cell. Biol. 11, 38-46.
7. Kolarov, J., Kolarova, N. & Nelson, N. (1990) A third ADP/ATP translocator gene in yeast, J. Biol. Chem. 265, 14195-14201.
8. Šabová, L., Zeman, I., Supek, F. & Kolarov, J. (1993) Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROXI factor, Eur. J. Biochem. 213, 547-553.
9. Betina, S., Gavurníková, G., Haviernik, P., Šabová, L. & Kolarov, J. (1995) Expression of the AAC2 gene encoding the major mitochondrial ADP/ATP carrier in Saccharomyces Cerevisiae is controlled at the transcriptional level by oxygen, heme and HAP2 factor, Eur. J. Biochem. 229, 651-657.
10. Zitomer, R. S. & Lowry, C. V. (1992) Regulation of gene expression by oxygen in Saccharomyces cerevisiae, Microbiol. Rev. 56, 1-11.
11. De Winde, J. H. & Grivell, L. A. (1993) Global regulation of mitochondrial biogenesis in Saccharomyces cerevisiae, Progr. Nucleic Acid Res. Mol. 46, 51-91.
12. Myers, A. M., Tzagoloff, A., Kinney, D. M. & Lusty, C. J. (1986) Yeast shutle and integrative vectors with multiple cloning sites for construction of laeZ fusion, Gene (Amst.) 45, 299-310.
13. Guarente, L. (1983) Yeast promoters and laeZ fusions designed to study the expression of cloned genes in yeast, Methods Enzymol. 101, 181-191.
14. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular cloning: a laboratory manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
15. Ito, H., Fukuda, Y., Murata, K. & Kimura, A. (1993) Transformation of intact yeast cells treated with alkali cations, J. Bacteriol. 153, 163-168.
16. 1 by HAP1 and HAP2/3/4, Mol. Cell. Biol. 11, 4934-4942.
17. Forsburg, S. L. & Guarente, L. (1988) Mutational analysis of upstream activation sequence 2 of CYCI gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site, Mol. Cell. Biol. 8, 647-654.
18. Keng, T. & Guarente, L. (1987) Constitutive expression of the yeast HEMI gene is actually a composite of activation and repression, Proc. Natl Acad. Sci. USA 84, 9113-9117.
19. Šubík, J., Kolarov, J. & Kováć, L. (1972) Obligatory requirement of intramitochondrial ATP for normal functionning of the eucaryotic cell, Biochem. Biophys. Res. Commun. 49, 192-198.