Radiation-induced germline mutations detected by a direct comparison of parents and first-generation offspring DNA sequences containing SNPs

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 596, Issue 1-2 SPEC. ISS., 2006, Pages 1-11

  Wu, Jianyu ^a   Morimyo, Mitsuoki ^a   Hongo, Etsuko ^a   Higashi, Tomoyasu ^a   Okamoto, Masanori ^a   Kawano, Akihiro ^a   Ohmachi, Yasushi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GAMMA RADIATION; GENE DELETION; GENE MUTATION; GENETIC RISK; IRRADIATION; MALE; MATING; MOUSE; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARENT; PRIORITY JOURNAL; PROGENY; RADIATION; RADIATION DOSE; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; BASE SEQUENCE; DNA; DNA PRIMERS; GERM-LINE MUTATION; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; POLYMORPHISM, SINGLE NUCLEOTIDE;

ANIMALIA;

EID: 33645970735     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.09.004     Document Type: Article

References (32)

1. Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation and reparability. Prog. Nucleic Acid Res. Mol. Biol. 35 (1988) 95-125
2. Le X.C., Xing J.Z., Lee J., Leadon S.A., and Weinfeld M. Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. Science 280 (1998) 1066-1069
3. ouget J. Measurement of DNA base damage in cells exposed to low doses of γ-radiation: comparison between the HPLC-EC and comet assays. Int. J. Radiat. Biol. 75 (1999) 51-58
4. Grosovsky A.J., de Boer J.G., de Jong P.J., Drobetsky E.A., and Glickman B.W. Base substitutions, frameshifts and small deletions constitute ionizing radiation-induced point mutations in mammalian cells. Proc. Natl. Acad. Sci. USA 85 (1988) 185-188
5. Miles C., and Meuth M. DNA sequence determination of γ-radiation-induced mutations of the hamster aprt locus. Mutat. Res. 227 (1989) 97-102
6. Nelson S.L., Giver C.R., and Grosovsky A.J. Spectrum of X-ray-induced mutations in the human hprt gene. Carcinogenesis 15 (1994) 495-502
7. Sankaranarayanan K. Ionizing radiation, genetic risk estimation and molecular biology: impact and inferences. Trends Genet. 9 (1991) 79-84
8. Russell W.L., and Kelly E.M. Mutation frequencies in male mice and the estimation of genetic hazards of radiation in men. Proc. Natl. Acad. Sci. USA 79 (1982) 542-544
9. Jeffreys A.J., Wilson V., and Thein S.L. Hypervariable 'minisatellite' regions in human DNA. Nature 314 (1985) 67-73
10. Jeffreys A.J., Royle N.J., Wilson V., and Wong Z. Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA. Nature 332 (1988) 278-281
11. Dubrova Y.E., Plumb M., Brown J., Fennelly J., Bois P., Goodhead D., and Jeffreys A.J. Stage specificity, dose response and doubling dose for mouse minisatellite germ-line mutation induced by acute radiation. Proc. Natl. Acad. Sci. USA 95 (1998) 6251-6255
12. Dubrova Y.E., Jeffreys A.J., and Malashenko A.M. Mouse minisatellite mutations induced by ionizing radiation. Nat. Genet. 5 (1993) 92-94
13. Dubrova Y.E., Nesterov V.N., Krouchinsky N.G., Ostapenko V.A., Neumann R., Neil D.L., and Jeffreys A.J. Human minisatellite mutation rate after the Chernobyl accident. Nature 380 (1996) 683-686
14. Dubrova Y.E., Nesterov V.N., Krouchinsky N.G., Ostapenko V.A., Vergnaud G., Giraudeau F., Buard J., and Jeffreys A.J. Further evidence for elevated human minisatellite mutation rate in Belarus, 8 years after the Chernobyl accident. Mutat. Res. 381 (1997) 267-278
15. National Radiological Protection Board. Chernobyl legacy. Radiol. Prot. Bull. 178 (1996) 5-6.
16. Kodaira M., Satoh C., Hiyama K., and Toyama K. Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells. Am. J. Hum. Genet. 57 (1995) 1275-1283
17. Satoh C., and Kodaira M. Effects of radiation on children. Nature 383 (1996) 226
18. Sambrook J., and Russell D.W. Molecular Cloning. third ed. (2001), Cold Spring Harbor Laboratory Press, New York
19. Drake J.W., Charlesworth B., Charlesworth D., and Crow J.F. Rates of spontaneous mutation. Genetics 148 (1998) 1667-1686
20. Sankaranarayanan K., and Chakraborty R. Ionizing radiation and genetic risks. XI. The doubling dose estimates from the mid-1950s to the present, the conceptual change to the use of human data for spontaneous mutation rates and mouse data for induced mutation rates for doubling dose calculations. Mutat. Res. 453 (2000) 107-127
21. Russell W.L., Bangham J.W., and Russell L.B. Differential response of mouse male germ-cell stages to radiation-induced specific-locus and dominant mutations. Genetics 148 (1998) 1567-1578
22. 252Cf radiation in cultured human cells. Int. J. Radiat. Biol. 52 (1987) 245-251
23. Hei T.K., Hall E.J., and Waldren C.A. Mutation induction and relative biological effectiveness of neutrons in mammalian cells. Radiat. Res. 115 (1988) 281-291
24. Byrne J., Rasmussen S.A., Steinhorn S.C., Connelly R.R., Myers M.H., Lynch C.F., Flannery J., Austin D.F., Holmes F.F., Holmes G.E., Strong L.C., and Mulvihill J.J. Genetic disease in the offspring of long-term survivors of childhood and adolescent cancer. Am. J. Hum. Genet. 62 (1998) 45-52
25. Kallen B., Karlsson P., Lundell M., Wallgren A., and Holm L.E. Outcome of reproduction in women irradiated for skin hemangioma in infancy. Radiat. Res. 149 (1998) 202-208
26. Neel J.V., and Lewis S.E. The comparative radiation genetics of humans and mice. Ann. Rev. Genet. 24 (1990) 327-362
27. Neel J.V. Update on the genetic effects of ionizing radiation. J. Am. Med. Assoc. 266 (1991) 698-701
28. Awa A.A., Honda T., Neriishi S., Sufuni T., Shimba H., Ohtaki K., Nakano M., Kodama Y., Itoh M., and Hamilton H.B. Cytogenetic study of the offspring of atomic bomb survivors, Hiroshima and Nagasaki. In: Obe G., and Basler A. (Eds). Cytogenetics; Basic and Applied Aspects (1987), Springer-Verlag, Berlin-Heidelberg 344-362
29. Neel J.V., Satoh C., Goriki K., Asakawa J., Fujita M., Takahashi N., Kageoka T., and Hazama R. Search for mutations altering protein charge and/or function in children of atomic bomb survivors: Final report. Am. J. Hum. Genet. 42 (1988) 663-676
30. Cattanach B.M., Burtenshaw M.D., Rasberry C., and Evans E.P. Large deletions and other gross forms of chromosome imbalance compatible with viability and fertility in the mouse. Nat. Genet. 3 (1993) 56-61
31. Russell L.B., and Russell W.L.R. Spontaneous mutations recovered as mosaics in the mouse specific-locus test. Proc. Natl. Acad. Sci. USA 93 (1996) 13072-13077
32. Nachman M.W., and Crowell S.L. Estimate of the mutation rate per nucleotide in humans. Genetics 156 (2000) 297-304