Chemical and electric transmission in the carotid body chemoreceptor complex

Biological Research

Volumn 38, Issue 4, 2005, Pages 341-345

  Eyzaguirre, Carlos ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Carotid body; Chemosensory activity; Glomus cells

Indexed keywords

ARTICLE; CAROTID BODY; CAROTID BODY CHEMORECEPTOR; CAROTID SINUS NERVE; CELL SECRETION; CHEMICAL ANALYSIS; CHEMOSENSITIVITY; ELECTRIC ACTIVITY; INTRACELLULAR RECORDING; NERVE CELL MEMBRANE POTENTIAL; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN;

GLOMUS;

EID: 33645969006     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602005000400005     Document Type: Article

References (40)

1. ABUDARA V, GARCES G, SÁEZ JC (1999) Cells of the carotid body express connexin43, which is up-regulated by cAMP. Brain Res 849: 25-33
2. ABUDARA V, JIANG RG, EYZAGUIRRE C (2001) Acidic regulation of junction channels between glomus cells in the rat carotid body: Possible role of [Ca2+]i. Brain Res 916: 50-60
3. ABUDARA V, JIANG RG, EYZAGUIRRE C (2002) Behaviour of junction channels between rat glomus cells during normoxia and hypoxia. J Neurophysiol 88: 639-649
4. ANICHKOV SV, BELEN'KII ML (1963) Pharmacology of the Carotid Body Chemoreceptors. New York: Pergamon. pp: 225
5. BARON M, EYZAGUIRRE C (1977) Effects of temperature on some membrane characteristics of caroted body cells. Am J Physiol Cell Physiol 2: C35-C46
6. BELMONTE C, EYZAGUIRRE C (1974) Efferent influences on carotid body chemoreceptors. J Neurophysiol 37: 1131-1143
7. BISCOE TJ, LALL A, SAMPSON SR (1970) Electron microscopic and electrophysiological studies on the carotid body following intracranial section of the glossopharyngeal nerve. J Physiol (Lond) 208: 133-152
8. DE CASTRO F (1926) Sur la structure et l'innervation de la glande intercarotidienne (glomus caroticum) de l'homme et des mammiferes et sur un nouveau systeme d'innervation autonome du nerf inter carotidien. Trab Lab Invest Biol 24: 365-432
9. EYZAGUIRRE C, KOYANO H, TAYLOR JR (1965) Presence of acetylcholine and transmitter release from carotid body chemoreceptors. J Physiol (Lond) 178: 463-476
10. EYZAGUIRRE C, ZAPATA P (1968) The release of acetylcholine (ACh) from carotid body tissues. Further study on the effects of ACh and of cholinergic blocking agents on the chemosensory discharge. J Physiol (Lond) 195: 589-607
11. EYZAGUIRRE C, ABUDARA V (1995) Possible role of coupling between glomus cells in carotid body chemoreception. Biol Signals 4: 263-270
12. EYZAGUIRRE C, ABUDARA V (1999) Carotid body glomus cells: Chemical secretion and transmission (modulation?) across cell-nerve ending junctions. Resp Physiol 115: 135-149
13. EYZAGUIRRE C, JIANG RG, ABUDARA V (2003) Electric and dye coupling between rat carotid body cells and between these cells and carotid nerve endings. In: LAHIRI S, SEMENZA G, PRABHAKAR N (eds) Oxygen Sensing: Responses and Adaptation to Hypoxia. New York: Marcel Dekker. pp: 331-352
14. FIDONE SJ, SATO A (1970) Efferent inhibition and antidromic depression of chemoreceptor A-fibers from the cat carotid body. Brain Res 22: 181-193
15. FIDONE SJ, WEINTRAUB ST, STAVINOHA WB (1976) Acetylcholine content of normal and denervated cat carotid bodies measured by pyrolysis gas chromatography/mass fragmentometry. J Neurochem 26: 1047-1049
16. FIEBER LA, McCLESKEY EW (1993) L-type calcium channels in Type 1 cells of the rat carotid body. J Neurophysiol 70: 1378-1384
17. FITZGERALD RS (2000) Oxygen and carotid body chemotransduction: The cholinergic hypothesis - A brief history and new evaluation. Respir Physiol 120: 89-104
18. GONZALEZ C, ALMARAZ L, OBESO A, RIGUAL R (1994) Carotid body chemoreceptors: From natural stimuli to sensory discharges. Physiol Rev 74: 829-98
19. GRUNDFEST H (1964) Evolution of electrophysiological varieties among sensory receptor systems. In: Essays on Physiological Evolutions. New York: Pergamon. pp: 107-138
20. GUAL A, MARSAL J (1987) Application of the chemiluminescence method to carotid body for detecting choline and acetylcholine. In: RIBEIRO JA, PALLOTT DJ (eds). Chemoreceptors in Respiratory Control. London: Croom Helms. pp: 108-113
21. HE L, DINGER B, FIDONE S (2005) Effect of chronic hypoxia on cholinergic chemotransmission in rat carotid body. J Appl Physiol 98: 614-619
22. HESS A, ZAPATA P (1972) Innervation of the cat carotid body: Normal and experimental studies. Fed Proc 31: 1365-1384
23. HEYMANS C, NEIL E (1958) Reflexogenic Areas of the Cardiovascular System. London: Churchill. pp: 207
24. ITURRIAGA R, ALCAYAGA J (2004) Neurotransmission in the carotid body: Transmitters and modulators between glomus cells and petrosal ganglion nerve terminals. Brain Res Rev 47: 46-53
25. JIANG RG, ZHANG XQ, EYZAGUIRRE C (1998) Hypoxia induced by Na2S204 increases [Na+]i in mouse glomus cells, an effect depressed by cobalt. Experiments with Na+ -selective microelectrodes and voltage clamping. Brain Res 797: 197-208
26. JIANG RG, EYZAGUIRRE C (2003a) Dye and electric coupling between carotid nerve terminals and glomus cells. Adv Exp Med Biol 536: 247-253
27. JIANG RG, EYZAGUIRRE C (2003b) Effects of hypobaric hypoxia on the intercellular coupling of glomus cells. Adv Exp Med Biol 536: 565-567
28. JIANG RG, EYZAGUIRRE C (2005) Calcium channels of cultured rat glomus cells in normoxia and acute hypoxia. Brain Res 1031: 56-66
29. KONDO H, IWASA H (1996) Re-examination of the carotid body ultrastructure with special attention to intercellular membrane appositions. Adv Exper Med Biol 410: 45-50
30. KONDO H (2002) Are there gap junctions between chief glomus, (type I) cells in the carotid body chemoreceptor? Microsc Res Tec 59: 227-233
31. MONTI-BLOCH L, EYZAGUIRRE C (1980) A comparative physiological and pharmacological study of cat and rabbit carotid bodies. Brain Res 193: 449-470
32. MONTI-BLOCH L, ABUDARA V, EYZAGUIRRE C (1993) Electrical communication between glomus cells of the rat carotid body. Brain Res 622: 119-131
33. MCDONALD DM (1981) Peripheral chemoreceptors: Structure-function relationships of the carotid body. In: HORNBEIN TF (ed) Regulation of Breathing. New York: Marcel Dekker. pp: 105-320
34. NEIL E, OREGAN RG (1971) The effects of electrical stimulation of the distal end of the cut sinus and aortic nerves on peripheral arterial chemoreceptor activity in the cat. J Physiol (Lond) 215: 15-32
35. REY S, DEL RÍO R, ALCAYAGA J, ITURRIAGA R (2004) Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia. J Physiol (Lond) 56: 577-586
36. VARAS R, ALCAYAGA J, ITURRIAGA R (2003) ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro. Brain Res 988: 154-163
37. VERNA A (1997) The mammalian carotid body: Morphological data. In GONZÁLEZ C (ed). The Carotid Body Chemoreceptors. New York: Springer. pp: 1-29
38. ZAPATA P (1997a) Chemosensory activity in the carotid nerve: Effects of physiological variables. In GONZÁLEZ C (ed) The Carotid Body Chemoreceptors. New York: Springer. pp: 97-118
39. ZAPATA P (1997b) Chemosensory activity in the carotid nerve: effects of pharmacological agents. In GONZÁLEZ C (ed) The Carotid Body Chemoreceptors. New York: Springer. pp: 119-146
40. ZHANG M, ZHONG H, VOLLMER C, NURSE CA (2000) Co-release of ATP and ACh mediate hypoxic signaling at rat carotid body chemoreceptors. J Physiol (Lond) 525: 143-158