ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro

Brain Research

Volumn 988, Issue 1-2, 2003, Pages 154-163

  Varas, Rodrigo ^a   Alcayaga, Julio ^b   Iturriaga, Rodrigo ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

ACh; ATP; Carotid body; Co transmission; Petrosal ganglion

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; HEXAMETHONIUM; SURAMIN;

ACIDOSIS; ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CAROTID BODY CHEMORECEPTOR; CAT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; FEMALE; GANGLION; MALE; MECHANICAL STIMULATION; NERVE CELL STIMULATION; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; PETROUS BONE; PRIORITY JOURNAL;

EID: 0142042947     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)03366-3     Document Type: Article

References (50)

1. Alcayaga J., Cerpa V., Retamal M., Arroyo J., Iturriaga R., Zapata P. Adenosine triphosphate-induced peripheral nerve discharges generated from the cat petrosal ganglion in vitro. Neurosci. Lett. 282:2000;185-188.
2. Alcayaga J., Eyzaguirre C. Electrophysiological evidence for the reconstitution of chemosensory units in co-cultures of carotid body and nodose ganglion neurons. Brain Res. 534:1990;324-328.
3. Alcayaga J., Iturriaga R., Zapata P. Flow-dependent chemosensory activity in the carotid body superfused in vitro. Brain Res. 455:1988;31-37.
4. Alcayaga J., Iturriaga R., Varas R., Arroyo J., Zapata P. Selective activation of carotid nerve fibers by acetylcholine applied to the cat petrosal ganglion in vitro. Brain Res. 786:1998;47-54.
5. Alcayaga J., Retamal M., Cerpa V., Arroyo J., Zapata P. Dopamine inhibits ATP-induced discharges generated from the petrosal ganglion in vitro. Brain Res. 966:2003;283-287.
6. Alcayaga J., Varas R., Arroyo J., Iturriaga R., Zapata P. Dopamine modulates carotid nerve responses induced by acetylcholine on the cat petrosal ganglion in vitro. Brain Res. 831:1999;97-103.
7. Belmonte C., Gallego R. Membrane properties of cat sensory neurones with chemoreceptor and baroreceptor endings. J. Physiol. (Lond.). 342:1983;603-614.
8. Bisgard G.E., Kressin N.A., Nielsen A.M., Daristotle L., Smith C.A., Forster H.V. Dopamine blockade alters ventilatory acclimatization to hypoxia in goats. Respir. Physiol. 69:1987;245-255.
9. Bock P. Adenine nucleotides in the carotid body. Cell Tissue Res. 206:1980;279-290.
10. 2 in cat carotid body. J. Appl. Physiol. 85:1998;1719-1726.
11. + currents of petrosal neurons with projections to the carotid body. J. Neurophysiol. 88:2002;2993-3002.
12. Docherty R.J., McQueen D.S. Inhibitory action of dopamine on carotid chemoreceptors. J. Physiol. (Lond.). 279:1978;425-436.
13. Donnelly D.F. Chemoreceptor nerve excitation may be not proportional to catecholamine secretion. J. Appl. Physiol. 81:1996;2330-2337.
14. Donnelly D.F. Developmental changes in membrane properties of chemoreceptor afferent neurones of the rat petrosal ganglion. J. Neurophysiol. 82:1999;209-215.
15. Dunn P.M., Zhong Y., Burnstock G. P2X receptors in peripheral neurones. Prog. Neurobiol. 65:2001;107-134.
16. Eyzaguirre C., Koyano H. Effects of hypoxia, hypercapnia, and pH on the chemoreceptor activity of the carotid body in vitro. J. Physiol. (Lond.). 178:1986;385-409.
17. Eyzaguirre C., Zapata P. Pharmacology of pH effects on carotid body chemoreceptors in vitro. J. Physiol. (Lond.). 195:1968;557-588.
18. Eyzaguirre C., Zapata P. Perspectives in carotid body research. J. Appl. Physiol. 57:1984;931-957.
19. Fidone S.J., González C., Yoshizaki Y. Effects of low oxygen on the release of dopamine from the rabbit carotid body in vitro. J. Physiol. (Lond.). 333:1982;93-110.
20. Fidone S.J., Weintraub S.T., Stavinoha W.B. Acetylcholine content of normal and denervated cat carotid bodies measured by pyrolysis gas chromatography/mass fragmentometry. J. Neurochem. 26:1976;1047-1049.
21. Fitzgerald R.S. Oxygen and carotid body chemotransduction: the cholinergic hypothesis - a brief history and new evaluation. Respir. Physiol. 120:2000;89-104.
22. Fitzgerald R.S., Shirahata M., Ide T. Further cholinergic aspects of carotid body chemotransduction of hypoxia in cats. J. Appl. Physiol. 82:1997;819-827.
23. Fitzgerald R.S., Shirahata M., Wang M.Y. Acetylcholine release from cat carotid bodies. Brain Res. 841:1999;53-61.
24. Gallego R. The ionic basis of action potentials in petrosal ganglion cells of the cat. J. Physiol. (Lond.). 342:1983;591-602.
25. Gallego R., Belmonte C. Axonal conduction velocity and input resistance in petrosal ganglion primary sensory neurones of the cat. Neurosci. Lett. 52:1984;117-122.
26. Gold M.S., Dastmalchi S., Levine J.D. Co-expression of nociceptor properties in dorsal root ganglion neurones from the adult rat in vitro. Neuroscience. 71:1996;265-275.
27. Gonzalez C., Almaraz L., Obeso A., Rigual R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74:1994;829-898.
28. Harper A.A., Lawson S.N. Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones. J. Physiol. (Lond.). 259:1985;31-46.
29. Hirasawa S., Mendoza J.A., Kobayashi C., Jacoby D.B., Chanrasagaran S., Fitzgerald R.S., Shirahata M. Diverse cholinergic receptor gene expression and localization in the cat carotid body and the petrosal ganglion. Chemoreception: From Cellular Signaling To Functional Plasticity. Proceedings of the XVth ISAC Symposium. 2002;85.
30. - on catecholamine efflux from the cat carotid body. J. Appl. Physiol. 84:1998;60-68.
31. Iturriaga R., Alcayaga J., Zapata P. Dissociation of hypoxia-induced chemosensory responses and catecholamine efflux in the cat carotid body superfused in vitro. J. Physiol. (Lond.). 497:1996;551-564.
32. Iturriaga R., Larraín C., Zapata P. Effects of dopamine blockade upon carotid chemosensory activity and its hypoxia-induced excitation. Brain Res. 663:1994;145-164.
33. Koga T., Bradley R.M. Biophysical properties and responses to transmitters of petrosal and geniculate ganglion neurones innervating the tongue. J. Neurophysiol. 84:2000;1404-1413.
34. Lee K.H., Chung K., Chung J.M., Coggeshall R.E. Correlation of the cell body size, axon size and signal conduction velocity for individually labelled dorsal root ganglion cells in the cat. J. Comp. Neurol. 243:1986;335-346.
35. McQueen D.S., Ribeiro J.A. On the specificity and type of receptor involved in carotid body chemoreceptor activation by adenosine in the cat. Br. J. Pharmacol. 80:1983;347-354.
36. Monti-Bloch L., Stensaas L.J., Eyzaguirre C. Carotid body grafts induce chemosensitivity in muscle nerve fibers of the cat. Brain Res. 270:1983;77-92.
37. Morales A., Ivorra I., Gallego R. Properties of glossopharyngeal sensory neurones in the petrosal ganglion of the cat. J. Physiol. (Lond.). 401:1987;340-346.
38. North R.A. Molecular physiology of P2X receptors. Physiol. Rev. 82:2002;1013-1067.
39. Prasad M., Fearon I.M., Zhang M., Laing M., Vollmer C., Nurse C.A. Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signaling. J. Physiol. (Lond.). 537:2001;667-677.
40. Reichling D.B., Barrat L., Levine J.D. Heat-induced cobalt entry: an assay for heat transduction in cultured rat dorsal root ganglion neurones. Neuroscience. 77:1997;291-294.
41. Rong W., Spyer K.M., Burnstock G. Activation and sensitisation of low and high threshold afferent fibers mediated by P2X receptors in the mouse urinary bladder. J. Physiol. (Lond.). 541:2002;591-600.
42. Shirahata M., Ishizawa Y., Rudisill M., Schofield B., Fitzgerald R.S. Presence of nicotinic acetylcholine receptors in cat carotid body afferent system. Brain Res. 814:1998;213-217.
43. Spergel D., Lahiri S. Differential modulation by extracellular ATP of carotid chemosensory responses. J. Appl. Physiol. 74:1993;3052-3056.
44. Varas R., Alcayaga J., Zapata P. Acetylcholine sensitivity in sensory neurones dissociated from the cat petrosal ganglion. Brain Res. 882:2000;201-205.
45. Varas R., Iturriaga R., Alcayaga C., Cerpa V., Alcayaga J. Current and voltage changes evoked by ACh and ATP in cat petrosal ganglion neurones. Soc. Neurosci. Abstr. 27:2001;288.12.
46. Wang Z.Z., Stensaas L.J., Dinger B., Fidone S.J. Immunocytochemical localization of choline acetyltransferase in the carotid body of the cat and rabbit. Brain Res. 498:1989;131-134.
47. Zapata P. Modulatory role of dopamine on arterial chemoreceptors. Adv. Biochem. Psychopharmacol. 16:1977;291-298.
48. Zhang M., Zhong H., Vollmer C., Nurse C.A. Co-release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors. J. Physiol. (Lond.). 525:2000;143-158.
49. Zhong H., Nurse C.A. Nicotinic acetylcholine sensitivity of rat petrosal sensory neurones in dissociated cell culture. Brain Res. 766:1997;153-161.
50. Zhong H., Zhang M., Nurse C.A. Synapse formation and hypoxic signalling in co-cultures of rat petrosal neurones and carotid body type 1 cells. J. Physiol. (Lond.). 503:1997;599-612.