Cochlear protection by local insulin-like growth factor-1 application using biodegradable hydrogel

Laryngoscope

Volumn 116, Issue 4, 2006, Pages 529-533

  Iwai, Koji ^a   Nakagawa, Takayuki ^a   Endo, Tsuyoshi ^a   Matsuoka, Yoshinori ^a   Kita, Tomoko ^a   Kim, Tae Soo ^a   Tabata, Yasuhiko ^b   Ito, Juichi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Acoustic trauma; Cochlea; Drug delivery; Growth factor; Hair cell; Protection; Rat

Indexed keywords

GLUTARALDEHYDE; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CELL LOSS; COCHLEA FENESTRA; COCHLEA INJURY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EVOKED BRAIN STEM AUDITORY RESPONSE; EXPOSURE; FUNCTION TEST; HAIR CELL; HISTOLOGY; HYDROGEL; NOISE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SOUND PRESSURE; TEMPORAL BONE; ANIMAL; BIOREMEDIATION; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; HYDROCOLLOID DRESSING; INNER EAR DISEASE; NOISE INJURY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, TOPICAL; ANIMALS; BANDAGES, HYDROCOLLOID; BIODEGRADATION, ENVIRONMENTAL; COCHLEAR DISEASES; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HEARING LOSS, NOISE-INDUCED; INSULIN-LIKE GROWTH FACTOR I; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 33645955238     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mlg.0000200791.77819.eb     Document Type: Article

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