1,4,9,10-Anthradiquinone as precursor for antitumor compounds

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 10, 2006, Pages 3599-3614

  Schenck, Lothar Werner ^a   Kuna, Krystina ^a   Frank, Walter ^a   Albert, Antje ^a   Asche, Christian ^a   Kucklaender, Uwe ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Azonine; Cytostatic activity; Enamines; Nenitzescu reaction; Quinones; Ring enlargement

Indexed keywords

1 (3 BENZYL 3,3A,6,12A TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 YL)ETHANONE; 1 (3,3A,6,12A TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXO 1 PHENYLNAPHTHO[2,3 D]INDOL 1 YL)ETHANONE; 1 [3,3A,6,12A TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXO 1 (4 TOLYL)NAPHTHO[2,3 D]INDOL 1 YL]ETHANONE; 1 CYANO 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOLE; 1,2,3,4,5,5A,8,14 OCTAHYDRO 5A,9 DIHYDROXY 3,3 DIMETHYL 5 PHENYLNAPHTHO[2,3 K]CARBAZOLE 1,8,14 TRIONE; 1,4,9,10 ANTHRADIQUINONE; 3 ACETYL 3A CHLORO 3A,11B DIHYDRO 5,11B DIHYDROXY 2 METHYL 1 (4 TOLYL)NAPHTHO[2,3 G]INDOL 6,11 DIONE; 3 ACETYL 3A CHLORO 3A,11B DIHYDRO 5,11B DIHYDROXY 2 METHYL 1 PHENYLNAPHTHO[2,3 G]INDOL 6,11 DIONE; ANTINEOPLASTIC AGENT; DIETHYL 4,4',5,5' TETRAHYDRO 1,1' DIISOBUTYL 2,2' DIMETHYL 5,5' DIOXO 1H,1' H 4,4' BINAPHTHO[2,3 G]INDOL 3,3' DICARBOXYLATE; DIETHYL 8 BENZYL 9,14 DIHYDRO 5 HYDROXY 2,7 DIMETHYL 9,14 DIOXO 8H BENZ[C]BENZO[B]FURO[6,7 F]AZONINE 3,6 DICARBOXYLATE; ETHYL 1 BENZYL 5 HYDROXY 2 METHYL 1H NAPHTHO[2,3 G]INDOL 3 CARBOXYLATE; ETHYL 3 (2,4 CHLOROBENZYL) 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 3 (4 CHLOROPHENYL) 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 3 (4 METHOXYPHENYL) 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 3 BENZYL 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 2 METHYL 6,12 DIOXO 3 (4 TOLYL)NAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 3,3A,6,12 TETRAHYDRO 3A,7 DIHYDROXY 3 (4 METHOXYBENZYL) 2 METHYL 6,12 DIOXONAPHTHO[2,3 D]INDOL 1 CARBOXYLATE; ETHYL 5 HYDROXY 1 (4 METHOXYBENZYL) 2 METHYL 1H NAPHTHO[2,3 G]INDOL 3 CARBOXYLATE; ETHYL 5 HYDROXY 1 (4 METHOXYPHENYL) 2 METHYL 1H NAPHTHO[2,3 G]INDOL 3 CARBOXYLATE; ETHYL 5 HYDROXY 2 METHYL 1 (4 TOLYL) 1H NAPHTHO[2,3 G]INDOL 3 CARBOXYLATE; ETHYL 6 BENZYL 6,13 DIHYDRO 9,12 DIHYDROXY 7 METHYL 5,13 DIOXO 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 6 BENZYL 6,9,12,13 TETRAHYDRO 7 METHYL 5,9,12,13 TETRAOXO 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 6,13 DIHYDRO 9,12 DIHYDROXY 6 (4 METHOXYBENZYL) 7 METHYL 5,13 DIOXO 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 6,13 DIHYDRO 9,12 DIHYDROXY 7 METHYL 5,13 DIOXO 6 (4 TOLYL) 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 6,9,12,13 TETRAHYDRO 7 METHYL 5,9,12,13 TETRAOXO 6 (4 TOLYL) 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 9,12 DIACETOXY 6 BENZYL 7 METHYL 5,13 DIOXO 6,13 TETRAHYDRO 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; ETHYL 9,12 DIACETOXY 6,13 DIHYDRO 7 METHYL 5,13 DIOXO 6 (4 TOLYL) 5H DIBENZ[C,F]AZONINE 8 CARBOXYLATE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; ELECTRON; HUMAN; HUMAN CELL; ISOMERIZATION; RING OPENING; SUBSTITUTION REACTION; SYNTHESIS; TUMOR GROWTH;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEOPLASMS;

BETULACEAE;

EID: 33645915741     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.01.026     Document Type: Article

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