Sm22.6 antigen is an inhibitor to human thrombin

Molecular and Biochemical Parasitology

Volumn 147, Issue 1, 2006, Pages 95-100

  Lin, Ya Ling ^a   He, Shiping ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Anti coagulant; Delayed coagulation time; Sm22.6 antigen; Thrombin inhibitor

Indexed keywords

GAMMA THROMBIN; PARASITE ANTIGEN; PROTEINASE; PROTOZOAL PROTEIN; RECOMBINANT ANTIGEN; THROMBIN;

ANTIGEN BINDING; ANTIGEN FUNCTION; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; HOST PARASITE INTERACTION; HUMAN; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN INTERACTION; SCHISTOSOMA MANSONI; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANIMALS; ANTICOAGULANTS; ANTIGENS, HELMINTH; HUMANS; RABBITS; RECOMBINANT PROTEINS; SCHISTOSOMA MANSONI; THROMBIN; WHOLE BLOOD COAGULATION TIME;

SCHISTOSOMA MANSONI;

EID: 33645893768     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2006.01.012     Document Type: Article

References (25)

1. Warren K.S. The contribution of worm burden and host responses to the development of heptocyte-splenic Schistosomiasis mansoni in mice. Am J Trop Med Hyg 12 (1963) 34-39
2. Samuelson J.C., and Caulfield J.P. Loss of covalently labeled glycoproteins and glycolipids from the surface of newly transformed schistomula of Schistosoma mansoni. J Cell Biol 94 (1982) 363-369
3. Jeffs S.A., Hagan P., Allen R., Correa-Oliveira R., Smithers S.R., and Simpson J.G. Molecular cloning and characterization of the 22-kDa adult Schistoma mansoni antigen recognized by antibodies from mice protectively vaccinated with isolated tegumental surface membranes. Mol Biochem Parasitol 46 (1991) 159-168
4. Dunne D.W., Webster M., Smith P., et al. The isolation of a 22 kDa band after SDS-PAGE of Schistosoma mansoni adult worms and its use to demonstrate that IgE responses against the antigen(s) it contains are associated with human resistance to reinfection. Parasite Immunol 19 (1997) 79-89
5. Auriault C., Damonneville M., Verwaerde C., et al. Rat IgE directed against Schistosoma mansoni schistosomula in vitro. Eur J Immunol 14 (1984) 132-138
6. Webster M., Roberts M., Fulford A.J., et al. Human IgE responses to rSm22.6 are associated with infection intensity rather than age per se, in a recently established focus of Schistosomiasis mansoni. Trop Med Int Health 3 (1998) 318-326
7. Webster M., Correa-Oliveira R., Gazzinelli G., et al. Factors affecting high and low human IgE responses to schistosome worm antigens in an area of Brazil endemic for Schistosoma mansoni and hookworm. Am J Trop Med Hyg 57 (1997) 487-494
8. Su C., Ma L., Wu H.W., and Shen L. Expression and identification of recombinant 22.6 kDa fusion protein of Schistosoma japonicum. Chin J Parasitol Parasite Dis 17 (1999) 205-208
9. Su C., Ma L., and Fan L.M. Construction of pCMV/Sj22.6 naked DNA vaccine of Schistosoma japonicum (Chinese mainland strain). Acta Univ Nanjing 19 (1999) 349-352
10. Wu H.W., Shen L., Zhang Z.S., and Wu G.L. Studies on immunoprotection in mice after immunization with Schistosoma japonicum 22.6 kDa recombinant protein. Chin J Parasitol Parasite Dis 17 (1999) 288-291
11. Hu S.M., Zhang Z.S., Li C.L., et al. Studies on immunoprotection in mice after immunization with the epitopes of 22.6 kDa antigen of Schistosoma japonicum. Chin J Schitsto Contr 13 (2001) 86-89
12. Milhon J.L., Thiboldeaux R.L., Glowac K., and Tracy J.W. Schistosoma japonicum GSH S-transferase Sj26 is not the molecular target of praziquantel action. Exp Parasitol 87 (1997) 268-274
13. Zhou J.C., Yi X.Y., Zeng X.F., et al. Detection of antibody in the sera of buffaloes immunized with recombinant 22 kDa tegumental antigen of Schistosoma japonicum. Chin J Schisto Contr 13 (2001) 90-93
14. Waine G.J., Becker M.M., Scott J.C., Kalinna B.H., Yang W., and McManus D.P. Purification of a recombinant Schistosoma japonicum antigen homologous to the 22-kDa membrane-associated antigen of S. mansoni, a putative vaccine candidate against schistomiasis. Gene 142 (1994) 259-263
15. Stein L.D., and David J.R. Cloning of a developmentally regulated tegument antigen of Schistosoma mansoni. Mol Biochem Parasitol 20 (1986) 253-264
16. Stirewalt M.A. Schistosome mansoni: cercaria to schistosomeule. Adv Parasitol 12 (1974) 115-182
17. Clegg J.A. In vitro cultivation of S. mansoni. Exp Parasitol 16 (1965) 133-147
18. Samuelson J.C., Caulfield J.P., and David J.R. Schistosome mansoni: post-transformational surface changes in schistosomula growth in vitro and in mice. Exp Parasitol 50 (1980) 369-383
19. Crabtree J.E., and Wilson R.A. Schistosoma mansoni: a scanning electron microscope study of the developing schistosomulum. Parasitol 81 (1980) 553-564
20. Francis P., and Bickle Q. Cloning of a 21.7-kDa vaccine-dominant antigen gene of Schistosoma mansoni reveals an EF hand-like motif. Mol Biochem Parasitol 50 (1992) 215-224
21. Amer A.M., el Defrawi I.E., el Sherif N.H., and el Khayat H.R. Is the coagulopathy of hepatosplenic schistosomiasis immune-related?. Blood Coagul Fibrinolysis 5 (1994) 789-793
22. Omran S.A., Amin H.M., el Bassiouni N.E., Essawy F.M., and Toiema S.M. Vitamin K dependent coagulation proteins in endemic hepatosplenomegaly in Egypt. J Clin Pathol 47 (1994) 502-504
23. Omran S.A., Amer A.M., el Kaliouby A.H., and Eldin A.A. Study of contact activation in endemic hepatosplenic hepatosplenomegaly. Blood Coagul Fibrinolysis 2 (1991) 659-662
24. Sonder S.A., and Fenton II J.W. Thrombin specificity with tripeptide chromogenic substrates: comparison of human and bovine thrombins with and without fibrinogen clotting activities. Clin Chem 32 (1986) 934-937
25. Towbin H., Staehelin T., and Gordon J. Electrophoresis transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76 (1979) 4350-4354