Supraspinally administered agmatine prevents the development of supraspinal morphine analgesic tolerance

European Journal of Pharmacology

Volumn 536, Issue 1-2, 2006, Pages 133-137

  Kitto, Kelley F ^a   Fairbanks, Carolyn A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Intracerebroventricular; Neuroprotection; Nitric oxide synthase; NMDA

Indexed keywords

AGMATINE; MORPHINE; SODIUM CHLORIDE;

ACUTE DRUG ADMINISTRATION; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG TOLERANCE; MALE; MORPHINE TOLERANCE; MOUSE; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PREMEDICATION; PRIORITY JOURNAL;

AGMATINE; ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MORPHINE; PAIN MEASUREMENT;

EID: 33645886923     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.01.053     Document Type: Article

References (25)

1. Aricioglu F., Paul I.A., and Regunathan S. Agmatine reduces only peripheral-related behavioral signs, not the central signs, of morphine withdrawal in nNOS deficient transgenic mice. Neurosci. Lett. 354 (2004) 153-157
2. Aricioglu-Kartal F., and Uzbay I.T. Inhibitory effect of agmatine on naloxone-precipitated abstinence syndrome in morphine dependent rats. Life Sci. 61 (1997) 1775-1781
3. Auguet M., Viossat I., Marin J.G., and Chabrier P.E. Selective inhibition of inducible nitric oxide synthase by agmatine. Jpn. J. Pharmacol. 69 (1995) 285-287
4. Bilsky E.J., Bernstein R.N., Hruby V.J., Rothman R.B., Lai J., and Porreca F. Characterization of antinociception to opioid receptor selective agonists. J. Pharmacol. Exp. Ther. 277 (1996) 491-501
5. Bilsky E.J., Inturrisi C.E., Sadee W., Hruby V.J., and Porreca F. Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice. Pain 68 (1996) 229-237
6. Davis A.M., and Inturrisi C.E. d-methadone blocks morphine tolerance and N-methyl-d-aspartate-induced hyperalgesia. J. Pharmacol. Exp. Ther. 289 (1999) 1048-1053
7. Demady D.R., Jianmongkol S., Vuletich J.L., Bender A.T., and Osawa Y. Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme. Mol. Pharmacol. 59 (2001) 24-29
8. Elliott K., Kest B., Man A., Kao B., and Inturrisi C.E. N-methyl-d-aspartate (NMDA) receptors, mu and kappa opioid tolerance, and perspectives on new analgesic drug development. Neuropsychopharmacology 13 (1995) 347-356
9. Fairbanks C.A., and Wilcox G.L. Acute tolerance to spinally administered morphine compares mechanistically with chronically induced morphine tolerance. J. Pharmacol. Exp. Ther. 282 (1997) 1408-1417
10. Fairbanks C.A., Schreiber K.L., Brewer K.L., Yu C.G., Stone L.S., Kitto K.F., Nguyen H.O., Grocholski B.M., Shoeman D.W., Kehl L.J., Regunathan S., Reis D.J., Yezierski R.P., and Wilcox G.L. Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Proc. Natl. Acad. Sci. 97 (2000) 10584-10589
11. Galea E., Regunathan S., Eliopoulos V., Feinstein D.L., and Reis D.J. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine. Biochem. J. 316 (1996) 247-249
12. Haley T.J., and McCormick W.G. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. Br. J. Pharmacol. 12 (1957) 12-15
13. Kitto K.F., Haley J.E., and Wilcox G.L. Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse. Neurosci. Lett. 148 (1992) 1-5
14. Kolesnikov Y., Jain S., and Pasternak G.W. Modulation of opioid analgesia by agmatine. Eur. J. Pharmacol. 296 (1996) 17-22
15. Li G., Regunathan S., Barrow C.J., Eshraghi J., Cooper R., and Reis D.J. Agmatine: an endogenous clonidine-displacing substance in the brain [see comments]. Science 263 (1994) 966-969
16. Morgan A.D., Campbell U.C., Fons R.D., and Carroll M.E. Effects of agmatine on the escalation of i.v. cocaine and fentanyl self-administration in rats. Pharmacol. Biochem. Behav. 72 (2002) 873-880
17. Nguyen H.O., Goracke-Postle C.J., Kaminski L.L., Overland A.O., Morgan A.D., and Fairbanks C.A. Neuropharmacokinetic and dynamic studies of agmatine. Ann. N.Y. Acad. Sci. 1009 (2003) 82-105
18. Pasternak G.W., Kolesnikov Y.A., and Babey A.M. Perspectives on the N-methyl-d-aspartate/nitric oxide cascade and opioid tolerance. Neuropsychopharmacology 13 (1995) 309-313
19. Pinthong D., Wright I.K., Hanmer C., Millns P., Mason R., Kendall D.A., and Wilson V.G. Agmatine recognizes alpha 2-adrenoceptor binding sites but neither activates nor inhibits alpha 2-adrenoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 351 (1995) 10-16
20. Quartilho A., Mata H.P., Ibrahim M.M., Vanderah T.W., Ossipov M.H., Lai J., Porreca F., and Malan Jr. T.P. Production of paradoxical sensory hypersensitivity by alpha 2-adrenoreceptor agonists. Anesthesiology 100 (2004) 1538-1544
21. Ramaswamy S., Pillai N.P., Gopalakrishnan V., and Ghosh M.N. Effect of clonidine on the chronic morphine tolerance and on the sensitivity of the smooth muscles in mice. Life Sci. 33 (1983) 1167-1172
22. Tallarida R.J., and Murray R.B. Manual of Pharmacological Calculations with Computer Programs (1987), Springer Verlag, New York 26-31
23. Tseng L.F., Loh H.H., and Wei E.T. Effects of clonidine on morphine withdrawal signs in the rat. Eur. J. Pharmacol. 30 (1975) 93-99
24. Wells J.L., Bartlett J.L., Ananthan S., and Bilsky E.J. In vivo pharmacological characterization of SoRI 9409, a nonpeptidic opioid mu-agonist/delta-antagonist that produces limited antinociceptive tolerance and attenuates morphine physical dependence. J. Pharmacol. Exp. Ther. 297 (2001) 597-605
25. Yang X.C., and Reis D.L. Agmatine selectively blocks the N-methyl-d-aspartate subclass of glutamate receptor channels in rat hippocampal neurons. J. Pharmacol. Exp. Ther. 288 (1999) 544-549