Interaction with σ1 protein, but not N-Methyl-D-aspartate receptor, is involved in the pharmacological activity of donepezil

Journal of Pharmacology and Experimental Therapeutics

Volumn 317, Issue 2, 2006, Pages 606-614

  Maurice, Tangui ^a,d   Meunier, Johann ^a   Feng, Bihua ^b   Ieni, John ^c   Monaghan, Daniel T ^b  

^a INSERM   (France)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c EISAI INC   (United States)

^d University of Montpellier   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; DIZOCILPINE; DONEPEZIL; ETHYLAMINE; IGMESINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (DIMETHYLAMINO)ETHYLAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECOMBINANT RECEPTOR; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; DRUG RECEPTOR BINDING; FEMALE; LEARNING DISORDER; MALE; MOLECULAR PROBE; MOUSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR AFFINITY; SWIMMING; XENOPUS;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BINDING SITES; CHOLINESTERASE INHIBITORS; CLONING, MOLECULAR; ETHYLENEDIAMINES; FEMALE; INDANS; LIGANDS; MALE; MAZE LEARNING; MICE; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OOCYTES; PIPERIDINES; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, SIGMA; SWIMMING; XENOPUS;

EID: 33645885043     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.097394     Document Type: Article

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