메뉴 건너뛰기




Volumn 45, Issue 4, 2005, Pages 503-513

Rosuvastatin: A high-potency HMG-CoA reductase inhibitor

Author keywords

Atorvastatin; Cholesterol; Dyslipidemia; Hyperlipidemia; Pravastatin; Review; Rosuvastatin; Simvastatin

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ROSUVASTATIN; STATIN; TRIACYLGLYCEROL; FLUOROBENZENE; PYRIMIDINE DERIVATIVE; SULFONAMIDE;

EID: 33645882200     PISSN: 15443191     EISSN: 15443450     Source Type: Journal    
DOI: 10.1331/1544345054475522     Document Type: Review
Times cited : (12)

References (43)
  • 1
    • 0037097814 scopus 로고    scopus 로고
    • Managing hyperlipidemia: Current and future roles of HMG-CoA reductase inhibitors
    • Lopez LM. Managing hyperlipidemia: current and future roles of HMG-CoA reductase inhibitors. Am J Health Syst Pharm. 2002;59:1173-9.
    • (2002) Am J Health Syst Pharm , vol.59 , pp. 1173-1179
    • Lopez, L.M.1
  • 2
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-9.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 3
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • for the West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, et al., for the West of Scotland Coronary Prevention Study Group. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med. 1995;333:1301-7.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 4
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • Sacks FM, Pfeffer MA, Moyé LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med. 1996;335:1001-9.
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moyé, L.A.3
  • 5
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS
    • Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. JAMA. 1998;279:1615-22.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 6
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
    • The Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med. 1998;339:1349-57.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 7
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 8
    • 0037126729 scopus 로고    scopus 로고
    • Evaluation, and Treatment of High Blood Cholesterol in Adults. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults 〈Adult Treatment Panel III〉. Final report
    • Expert Panel on Detection
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults 〈Adult Treatment Panel III〉. Final report. Circulation. 2002;106:3143-421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 9
    • 0042512336 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice: Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice
    • De Backer G, Ambrosioni E, Borch-Johnsen K, et al. European guidelines on cardiovascular disease prevention in clinical practice: Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J. 2003;24:1601-10.
    • (2003) Eur Heart J , vol.24 , pp. 1601-1610
    • De Backer, G.1    Ambrosioni, E.2    Borch-Johnsen, K.3
  • 10
    • 0034723758 scopus 로고    scopus 로고
    • The Lipid Treatment Assessment Project (L-TAP): A multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals
    • Pearson TA, Laurora I, Chu H, Kafonek S. The Lipid Treatment Assessment Project (L-TAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals. Arch Intern Med. 2000;160:459-67.
    • (2000) Arch Intern Med , vol.160 , pp. 459-467
    • Pearson, T.A.1    Laurora, I.2    Chu, H.3    Kafonek, S.4
  • 11
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses 〈STELLAR Trial〉
    • Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses 〈STELLAR Trial〉. Am J Cardiol. 2003;92:152-60.
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3
  • 12
    • 85030519958 scopus 로고    scopus 로고
    • Crestor 〈rosuvastatin calcium〉 tablets [package insert, Wilmington, Del, AstraZeneca Pharmaceuticals LP; March 2005
    • Crestor 〈rosuvastatin calcium〉 tablets [package insert]. Wilmington, Del.: AstraZeneca Pharmaceuticals LP; March 2005.
  • 13
    • 0035825928 scopus 로고    scopus 로고
    • Preclinical and clinical pharmacology of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
    • McTaggart F, Buckett L, Davidson R, et al. Preclinical and clinical pharmacology of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Am J Cardiol. 2001;87(suppl):28B-32B.
    • (2001) Am J Cardiol , vol.87 , Issue.SUPPL.
    • McTaggart, F.1    Buckett, L.2    Davidson, R.3
  • 14
    • 0036139706 scopus 로고    scopus 로고
    • Rosuvastatin: A highly efficacious statin for the treatment of dyslipidaemia
    • Davidson MH. Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. Expert Opin Investig Drugs. 2002;11:125-41.
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 125-141
    • Davidson, M.H.1
  • 15
    • 0037382016 scopus 로고    scopus 로고
    • Pharmacologic characteristics of statins. Clin Cardiol
    • suppl III:III-32-8
    • McKenney JM. Pharmacologic characteristics of statins. Clin Cardiol. 2003;26 (suppl III):III-32-8.
    • (2003) , pp. 26
    • McKenney, J.M.1
  • 16
    • 0036142105 scopus 로고    scopus 로고
    • Rosuvastatin for the treatment of patients with hypercholesterolemia
    • Chong PH, Yim BT. Rosuvastatin for the treatment of patients with hypercholesterolemia. Ann Pharmacother. 2002;36:93-101.
    • (2002) Ann Pharmacother , vol.36 , pp. 93-101
    • Chong, P.H.1    Yim, B.T.2
  • 17
    • 0242509092 scopus 로고    scopus 로고
    • Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers
    • Martin PD, Warwick MJ, Dane AL, et al. Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers. Clin Ther. 2003;25:2553-63.
    • (2003) Clin Ther , vol.25 , pp. 2553-2563
    • Martin, P.D.1    Warwick, M.J.2    Dane, A.L.3
  • 18
    • 0035451307 scopus 로고    scopus 로고
    • Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia
    • Olsson AG, Pears J, McKellar J, et al. Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia. Am J Cardiol. 2001;88:504-8.
    • (2001) Am J Cardiol , vol.88 , pp. 504-508
    • Olsson, A.G.1    Pears, J.2    McKellar, J.3
  • 19
    • 1042308426 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, dose-ranging study of rosuvastatin in Japanese hypercholesterolemic subjects [abstract]
    • Saito Y, Goto Y, Dane A, Strutt K. Randomized, double-blind, placebo-controlled, dose-ranging study of rosuvastatin in Japanese hypercholesterolemic subjects [abstract]. Atherosclerosis. 2002;3(suppl):1999.
    • (1999) Atherosclerosis. 2002 , vol.3 , Issue.SUPPL.
    • Saito, Y.1    Goto, Y.2    Dane, A.3    Strutt, K.4
  • 20
    • 0037498860 scopus 로고    scopus 로고
    • Group on behalf of mercury. Effects of switching to rosuvastatin from atrovastatin or other statins on achievement of international low-density lipoprotein cholesterol goals: Mercury I trial [abstract]
    • Schuster H. Study Group on behalf of mercury. Effects of switching to rosuvastatin from atrovastatin or other statins on achievement of international low-density lipoprotein cholesterol goals: Mercury I trial [abstract]. J Am Coll Cardiol. 2003;41:227-8.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 227-228
    • Study, S.H.1
  • 21
    • 2342541129 scopus 로고    scopus 로고
    • Switching to rosuvastatin from other statins has beneficial effects on lipid ratios [abstract]
    • Schuster H, Cheung, Bonnet J, et al. Switching to rosuvastatin from other statins has beneficial effects on lipid ratios [abstract]. Atherosclerosis. 2003;4(suppl):81.
    • (2003) Atherosclerosis , vol.4 , Issue.SUPPL. , pp. 81
    • Schuster, H.1
  • 22
    • 0036915307 scopus 로고    scopus 로고
    • Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia
    • Olsson AG, Istad H, Luurila O, et al. Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia. Am Heart J. 2002;:144:1044-51.
    • (2002) Am Heart J , vol.144 , pp. 1044-1051
    • Olsson, A.G.1    Istad, H.2    Luurila, O.3
  • 23
    • 0036910821 scopus 로고    scopus 로고
    • Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: A randomized, double-blind, 52-week trial
    • Brown WV, Bays HE, Hassman DR, et al. Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial. Am Heart J. 2002;144:1036-43.
    • (2002) Am Heart J , vol.144 , pp. 1036-1043
    • Brown, W.V.1    Bays, H.E.2    Hassman, D.R.3
  • 24
    • 0036467895 scopus 로고    scopus 로고
    • Comparison of effects on low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with rosuvastatin versus atorvastatin in patients with type IIa or IIb hypercholesterolemia
    • Davidson M, Ma P, Stein EA, et al. Comparison of effects on low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with rosuvastatin versus atorvastatin in patients with type IIa or IIb hypercholesterolemia. Am J Cardiol. 2002;89:268-75.
    • (2002) Am J Cardiol , vol.89 , pp. 268-275
    • Davidson, M.1    Ma, P.2    Stein, E.A.3
  • 25
    • 84992920491 scopus 로고    scopus 로고
    • Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolemic patients: A randomized, double-blind study
    • Paoletti R, Fahmy M, Mahla G, et al. Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolemic patients: a randomized, double-blind study. J Cardiovasc Risk. 2001;8:383-90.
    • (2001) J Cardiovasc Risk , vol.8 , pp. 383-390
    • Paoletti, R.1    Fahmy, M.2    Mahla, G.3
  • 26
    • 0003263284 scopus 로고    scopus 로고
    • Evaluation of rosuvastatin in the treatment of hypercholesterolemia in postmenopausal women [abstract]
    • Shepherd J, Packard C, Smith K, et al. Evaluation of rosuvastatin in the treatment of hypercholesterolemia in postmenopausal women [abstract]. Atherosclerosis. 2002;3(suppl):205.
    • (2002) Atherosclerosis , vol.3 , Issue.SUPPL. , pp. 205
    • Shepherd, J.1    Packard, C.2    Smith, K.3
  • 27
    • 0003141815 scopus 로고    scopus 로고
    • Effect of rosuvastatin on LDL-cholesterol, mevalonic acid, and other lipid measurements in patients with homozygous familial hypercholesterolemia [abstract]
    • Marais D, Raal F, Stein E, et al. Effect of rosuvastatin on LDL-cholesterol, mevalonic acid, and other lipid measurements in patients with homozygous familial hypercholesterolemia [abstract]. Atherosclerosis. 2002;3(suppl):159.
    • (2002) Atherosclerosis , vol.3 , Issue.SUPPL. , pp. 159
    • Marais, D.1    Raal, F.2    Stein, E.3
  • 28
    • 2342446689 scopus 로고    scopus 로고
    • Response to lipid-lowering treatment with rosuvastatin in diabetic patients with the metabolic syndrome [abstract]
    • Durrington P, Tuomilehto J, Hamann A, et al. Response to lipid-lowering treatment with rosuvastatin in diabetic patients with the metabolic syndrome [abstract]. Diabetic Med. 2003;20(suppl 2):100.
    • (2003) Diabetic Med , vol.20 , Issue.SUPPL. 2 , pp. 100
    • Durrington, P.1    Tuomilehto, J.2    Hamann, A.3
  • 29
    • 0037422068 scopus 로고    scopus 로고
    • Efficacy of rosuvastatin 10 mg in patients with the metabolic syndrome
    • Ballantyne CM, Stein EA, Paoletti R, et al. Efficacy of rosuvastatin 10 mg in patients with the metabolic syndrome. Am J Cardiol. 2003;91(suppl):25C- 28C.
    • (2003) Am J Cardiol , vol.91 , Issue.SUPPL.
    • Ballantyne, C.M.1    Stein, E.A.2    Paoletti, R.3
  • 30
    • 0037422116 scopus 로고    scopus 로고
    • Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemia patients and in special population groups
    • Blasetto JW, Stein EA, Brown WV, et al. Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemia patients and in special population groups. Am J Cardiol. 2003;91(suppl):3C-10C.
    • (2003) Am J Cardiol , vol.91 , Issue.SUPPL.
    • Blasetto, J.W.1    Stein, E.A.2    Brown, W.V.3
  • 31
    • 11844259382 scopus 로고    scopus 로고
    • Standards of medical care in diabetes
    • American Diabetes Association
    • American Diabetes Association. Standards of medical care in diabetes. Diabetes Care. 2005;28:S4-S36.
    • (2005) Diabetes Care , vol.28
  • 32
    • 0042168932 scopus 로고    scopus 로고
    • Reducing coronary heart disease associated with type 2 diabetes: Lifestyle intervention and treatment of dyslipidemia
    • Tuomilehto J. Reducing coronary heart disease associated with type 2 diabetes: lifestyle intervention and treatment of dyslipidemia. Diabetes Res Clin Pract. 2003;61:S27-S34.
    • (2003) Diabetes Res Clin Pract , vol.61
    • Tuomilehto, J.1
  • 33
    • 0037846468 scopus 로고    scopus 로고
    • Beneficial effects of rosuvastatin alone and in combination with extended-release niacin in patients with a combined hyperlipidemia and low high-density lipoprotein cholesterol levels
    • Capuzzi DM, Morgan JM, Weiss RJ, et al. Beneficial effects of rosuvastatin alone and in combination with extended-release niacin in patients with a combined hyperlipidemia and low high-density lipoprotein cholesterol levels. Am J Cardiol. 2003;91:1304-10.
    • (2003) Am J Cardiol , vol.91 , pp. 1304-1310
    • Capuzzi, D.M.1    Morgan, J.M.2    Weiss, R.J.3
  • 34
    • 0037036822 scopus 로고    scopus 로고
    • ACC/AHA/NHLBI clinical advisory on the use and safety of statins
    • Pasternak RC, Smith SC Jr, Bairey-Merz CN, et al. ACC/AHA/NHLBI clinical advisory on the use and safety of statins. J Am Coll Cardiol. 2002;40:567-72.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 567-572
    • Pasternak, R.C.1    Smith Jr, S.C.2    Bairey-Merz, C.N.3
  • 35
    • 0141612021 scopus 로고    scopus 로고
    • Benefit-risk assessment of rosuvastatin 10 to 40 milligrams
    • Brewer HB Jr. Benefit-risk assessment of rosuvastatin 10 to 40 milligrams. Am J Cardiol. 2003;92(suppl):23K-29K.
    • (2003) Am J Cardiol , vol.92 , Issue.SUPPL.
    • Brewer Jr., H.B.1
  • 36
    • 20544432480 scopus 로고    scopus 로고
    • The safety of rosuvastatin as used in common clinical practice: A postmarketing analysis
    • Alsheikh-Ali AA, Ambrose MS, Kuvin JT, Karas RH. The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis. Circulation. 2005;111:3051-7.
    • (2005) Circulation , vol.111 , pp. 3051-3057
    • Alsheikh-Ali, A.A.1    Ambrose, M.S.2    Kuvin, J.T.3    Karas, R.H.4
  • 37
    • 20544443723 scopus 로고    scopus 로고
    • The issue of statin safety: Where do we stand [editorial]?
    • Grundy SM. The issue of statin safety: where do we stand [editorial]? Circulation. 2005;111:3016-9.
    • (2005) Circulation , vol.111 , pp. 3016-3019
    • Grundy, S.M.1
  • 38
    • 85030519211 scopus 로고    scopus 로고
    • Department of Health and Human Service. Re: Docket No. 2004P-0113/CP1. Accessed at: www.fda.gov.cder/drug/infopage/rosuvastatin/crestor_CP.pdf, June 14, 2005.
    • Department of Health and Human Service. Re: Docket No. 2004P-0113/CP1. Accessed at: www.fda.gov.cder/drug/infopage/rosuvastatin/crestor_CP.pdf, June 14, 2005.
  • 40
    • 1842829905 scopus 로고    scopus 로고
    • Rosuvastatin-induced arrest in progression of renal disease
    • Vidt D, Cressman M, Harris S, et al. Rosuvastatin-induced arrest in progression of renal disease. Cardiology. 2004;102:52-60.
    • (2004) Cardiology , vol.102 , pp. 52-60
    • Vidt, D.1    Cressman, M.2    Harris, S.3
  • 41
    • 0035826856 scopus 로고    scopus 로고
    • Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation
    • Undas A, Brummel K, Musial J, et al. Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation. 2001;103:2248-53.
    • (2001) Circulation , vol.103 , pp. 2248-2253
    • Undas, A.1    Brummel, K.2    Musial, J.3
  • 42
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomized controlled trial
    • for the ASCOT Investigators
    • Sever P, Dahlöf B, Paulter N, et al. for the ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomized controlled trial. Lancet. 2003;361:1149-55.
    • (2003) Lancet , vol.361 , pp. 1149-1155
    • Sever, P.1    Dahlöf, B.2    Paulter, N.3
  • 43
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • for the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators
    • Cannon C, Braunwald E, McCabe C, et al. for the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med. 2004;350:1495-504.
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.1    Braunwald, E.2    McCabe, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.