Aqueous diastereoselective hydrogenation of folic acid to tetrahydrofolic acid in the presence of water-soluble Rh and Ir diphosphine complexes

Tetrahedron Asymmetry

Volumn 17, Issue 4, 2006, Pages 544-549

  Pugin, Benoît ^a   Groehn, Viola ^b   Moser, Rudolf ^b   Blaser, Hans Ulrich ^a  

^a SOLVIAS AG   (Switzerland)

^b Eprova AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; IRIDIUM COMPLEX; PHOSPHINE DERIVATIVE; RHODIUM COMPLEX; SODIUM CHLORIDE; TETRAHYDROFOLIC ACID; WATER;

AQUEOUS SOLUTION; ARTICLE; ASYMMETRIC SYNTHESIS; CHEMICAL REACTION; DIASTEREOISOMER; DRUG SYNTHESIS; HIGH TEMPERATURE; HYDROGENATION; HYDROPHILICITY; PHARMACEUTICAL ENGINEERING; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; TEMPERATURE DEPENDENCE;

EID: 33645874225     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2005.12.034     Document Type: Article

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