메뉴 건너뛰기




Volumn 23, Issue 3-6, 1997, Pages 174-178

Adverse effects of hyperhomocysteinemia and their management by folic acid

Author keywords

Adenosylhomocysteine; Adenosylmethionine; Cardiovascular risk factors; Erythrocytes; Homocysteine; Methylation reactions; Uremia

Indexed keywords

DEXTRO ARGININE; FOLIC ACID; HOMOCYSTEINE; MEMBRANE PROTEIN; S ADENOSYLHOMOCYSTEINE;

EID: 0030723158     PISSN: 03780392     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (18)

References (41)
  • 1
    • 0027534543 scopus 로고
    • Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells
    • Jakuboski H, Goldman E: Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells. FEBS Lett 1993;317:237-240.
    • (1993) FEBS Lett , vol.317 , pp. 237-240
    • Jakuboski, H.1    Goldman, E.2
  • 2
    • 0027493344 scopus 로고
    • Chemical pathology of homocysteine. I. Atherogenesis
    • McCully KS: Chemical pathology of homocysteine. I. Atherogenesis. Ann Clin Lab Sci 1993;23:477-493.
    • (1993) Ann Clin Lab Sci , vol.23 , pp. 477-493
    • McCully, K.S.1
  • 3
    • 0000363006 scopus 로고
    • Disorders of transulfuration
    • Scriver CR, Beaudet AL, Sly WS, Valle D (eds). New York, Mc Graw Hill
    • Mudd SH, Levy HL, Skovby F: Disorders of transulfuration; in Scriver CR, Beaudet AL, Sly WS, Valle D (eds): The Metabolic Basis of Inherited Disease. New York, Mc Graw Hill, 1989, p 693.
    • (1989) The Metabolic Basis of Inherited Disease , pp. 693
    • Mudd, S.H.1    Levy, H.L.2    Skovby, F.3
  • 4
    • 0026533906 scopus 로고
    • The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine
    • Selhub J, Miller JW: The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. Am J Clin Nutr 1992;55:131-138.
    • (1992) Am J Clin Nutr , vol.55 , pp. 131-138
    • Selhub, J.1    Miller, J.W.2
  • 5
    • 0014690840 scopus 로고
    • The specificity of S-adenosylmethionine derivatives in methyl transfer reactions
    • Zappia V, Zydek-Cwick CR, Schlenk F: The specificity of S-adenosylmethionine derivatives in methyl transfer reactions. J Biol Chem l969;244:4499-4505.
    • (1969) J Biol Chem , vol.244 , pp. 4499-4505
    • Zappia, V.1    Zydek-Cwick, C.R.2    Schlenk, F.3
  • 6
    • 0002616156 scopus 로고
    • The role of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in the control of biologic methylations
    • Cavallini D, Gaull GE, Zappia V (eds). New York, Plenum
    • Cantoni GL, Chiang PK: The role of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in the control of biologic methylations; in Cavallini D, Gaull GE, Zappia V (eds): Natural Sulfur Compounds: Novel Biochemical and Structural Aspects. New York, Plenum, 1980, p 67.
    • (1980) Natural Sulfur Compounds: Novel Biochemical and Structural Aspects , pp. 67
    • Cantoni, G.L.1    Chiang, P.K.2
  • 7
    • 0021212302 scopus 로고
    • Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes: Physiological consequences
    • Barber JR, Clarke S: Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes: Physiological consequences. J Biol Chem 1984;259:7115-7122.
    • (1984) J Biol Chem , vol.259 , pp. 7115-7122
    • Barber, J.R.1    Clarke, S.2
  • 8
    • 0026034240 scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease
    • Kang SS, Wong PWK, Susmano A, Sora J, Norusis M, Ruggie N: Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease. Am J Hum Genet 1991; 48:536-545.
    • (1991) Am J Hum Genet , vol.48 , pp. 536-545
    • Kang, S.S.1    Wong, P.W.K.2    Susmano, A.3    Sora, J.4    Norusis, M.5    Ruggie, N.6
  • 9
    • 0017284939 scopus 로고
    • The pathogenesis of coronary artery disease: A possible role for methionine metabolism
    • Wilcken DEL, Wilcken B: The pathogenesis of coronary artery disease: A possible role for methionine metabolism. J Clin Invest 1976;57:1079-1082.
    • (1976) J Clin Invest , vol.57 , pp. 1079-1082
    • Wilcken, D.E.L.1    Wilcken, B.2
  • 12
    • 0027523674 scopus 로고
    • Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: The atherosclerosis Risk in Communities Study
    • Malinow MR, Nieto FJ, Szklo M, Chambless LE, Bond G: Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: The atherosclerosis Risk in Communities Study. Circulation 1993;87:1107-1113.
    • (1993) Circulation , vol.87 , pp. 1107-1113
    • Malinow, M.R.1    Nieto, F.J.2    Szklo, M.3    Chambless, L.E.4    Bond, G.5
  • 15
    • 0017197285 scopus 로고
    • Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response to its genesis
    • Harker LA, Ross R, Slichter SJ, Scott CR: Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response to its genesis. J Clin Invest 1976;58:731-741.
    • (1976) J Clin Invest , vol.58 , pp. 731-741
    • Harker, L.A.1    Ross, R.2    Slichter, S.J.3    Scott, C.R.4
  • 16
    • 0343505929 scopus 로고
    • Folic acid fortification - Prevention opportunity of the decade?
    • Oakley GP: Folic acid fortification - Prevention opportunity of the decade? Irish J Med Sci 1995; 164:S14.
    • (1995) Irish J Med Sci , vol.164
    • Oakley, G.P.1
  • 18
    • 0026486960 scopus 로고
    • Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: A potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism
    • Harpel PC, Chang VT, Bort W: Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: A potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism. Proc Natl Acad Sci USA 1992;89:10193-10197.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10193-10197
    • Harpel, P.C.1    Chang, V.T.2    Bort, W.3
  • 19
    • 0027358021 scopus 로고
    • Biochemical model reactions on the prooxidative activity of homocysteine
    • Preibisch G, Kuffner C, Elstner EF: Biochemical model reactions on the prooxidative activity of homocysteine. J Biosci 1993;48:58-62.
    • (1993) J Biosci , vol.48 , pp. 58-62
    • Preibisch, G.1    Kuffner, C.2    Elstner, E.F.3
  • 20
    • 0027288252 scopus 로고
    • Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor
    • Hajjar KA: Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Invest 1993;91:2873-2879.
    • (1993) J Clin Invest , vol.91 , pp. 2873-2879
    • Hajjar, K.A.1
  • 21
    • 0022472013 scopus 로고
    • Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator
    • Rodgers GM, Kane WH: Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest 1986;77:1909-1916.
    • (1986) J Clin Invest , vol.77 , pp. 1909-1916
    • Rodgers, G.M.1    Kane, W.H.2
  • 22
    • 0026773724 scopus 로고
    • An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells
    • Hayashi T, Honda G, Suzuki K: An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells. Blood 1992;79:2930-2936.
    • (1992) Blood , vol.79 , pp. 2930-2936
    • Hayashi, T.1    Honda, G.2    Suzuki, K.3
  • 23
    • 0027535171 scopus 로고
    • Cardiac and cerebrovascular disease in chronic uremia
    • Parfrey PS: Cardiac and cerebrovascular disease in chronic uremia. Am J Kidney Dis 1993;21:77-80.
    • (1993) Am J Kidney Dis , vol.21 , pp. 77-80
    • Parfrey, P.S.1
  • 24
    • 0019153170 scopus 로고
    • Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysis
    • Wilcken DEL, Gupta VJ, Reddy SG: Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysis. Clin Sci 1980;58:427-430.
    • (1980) Clin Sci , vol.58 , pp. 427-430
    • Wilcken, D.E.L.1    Gupta, V.J.2    Reddy, S.G.3
  • 29
    • 10544252271 scopus 로고    scopus 로고
    • Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and piridoxine concentrations
    • Robinson K, Gupta A, Dennis V, Arheart D, Chaudhary D, Green R, Vigo P, Mayer EL, Selhub J, Kutner M, Jacobsen DW: Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and piridoxine concentrations. Circulation, 1996;94:2743-2748.
    • (1996) Circulation , vol.94 , pp. 2743-2748
    • Robinson, K.1    Gupta, A.2    Dennis, V.3    Arheart, D.4    Chaudhary, D.5    Green, R.6    Vigo, P.7    Mayer, E.L.8    Selhub, J.9    Kutner, M.10    Jacobsen, D.W.11
  • 30
    • 0029911977 scopus 로고    scopus 로고
    • Homocysteinemia and vascular disease in end stage renal disease
    • Dennis VW, Robinson K: Homocysteinemia and vascular disease in end stage renal disease. Kidney Int 1996;50:S11-S17.
    • (1996) Kidney Int , vol.50
    • Dennis, V.W.1    Robinson, K.2
  • 31
    • 0028919731 scopus 로고
    • Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia
    • Perna AF, Ingrosso D, De Santo NG, Galletti P, Zappia V: Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia. Kidney Int 1995;47:247-253.
    • (1995) Kidney Int , vol.47 , pp. 247-253
    • Perna, A.F.1    Ingrosso, D.2    De Santo, N.G.3    Galletti, P.4    Zappia, V.5
  • 32
    • 0027302413 scopus 로고
    • Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure: Evidence for high levels of the natural inhibitor S-adenosylhomocysteine
    • Perna AF, Ingrosso D, Galletti P, Zappia V, De Santo NG: Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure: Evidence for high levels of the natural inhibitor S-adenosylhomocysteine. J Clin Invest 1993;91:2497-2503.
    • (1993) J Clin Invest , vol.91 , pp. 2497-2503
    • Perna, A.F.1    Ingrosso, D.2    Galletti, P.3    Zappia, V.4    De Santo, N.G.5
  • 33
    • 0028927865 scopus 로고
    • Protein damage and methylation mediated repair in the erythrocyte
    • Galletti P, Ingrosso D, Manna C, Clemente G, Zappia V: Protein damage and methylation mediated repair in the erythrocyte. Biochem J 1995;306:313-325.
    • (1995) Biochem J , vol.306 , pp. 313-325
    • Galletti, P.1    Ingrosso, D.2    Manna, C.3    Clemente, G.4    Zappia, V.5
  • 34
    • 0030712472 scopus 로고    scopus 로고
    • D-aspartate content of erythrocyte membrane proteins is decreased in uremia: Implications for the repair of damaged proteins
    • Perna AF, D'Aniello A, Lowenson JD, Clarke S, De Santo NG, Ingrosso D: D-aspartate content of erythrocyte membrane proteins is decreased in uremia: Implications for the repair of damaged proteins. J Am Soc Nephrol 1997;8:95-104.
    • (1997) J am Soc Nephrol , vol.8 , pp. 95-104
    • Perna, A.F.1    D'Aniello, A.2    Lowenson, J.D.3    Clarke, S.4    De Santo, N.G.5    Ingrosso, D.6
  • 35
    • 0029788271 scopus 로고    scopus 로고
    • Membrane protein damage and methylation reactions in chronic renal failure
    • Perna AF, Ingrosso D, Galletti P, Zappia V, De Santo NG: Membrane protein damage and methylation reactions in chronic renal failure. Kidney Int 1996;50:358-366.
    • (1996) Kidney Int , vol.50 , pp. 358-366
    • Perna, A.F.1    Ingrosso, D.2    Galletti, P.3    Zappia, V.4    De Santo, N.G.5
  • 36
    • 0023949170 scopus 로고
    • Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: Possible implications for prevention of vascular disease
    • Wilcken DEL, Dudman NPB, Tyrrell PA, Robertson MR: Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: Possible implications for prevention of vascular disease. Metabolism 1988;37:697-701.
    • (1988) Metabolism , vol.37 , pp. 697-701
    • Wilcken, D.E.L.1    Dudman, N.P.B.2    Tyrrell, P.A.3    Robertson, M.R.4
  • 39
    • 0007510927 scopus 로고
    • Folate in tissues and cells: Support for a 'two tier' hypothesis of one carbon metabolism
    • Cooper BA, Whitehead MV (eds). Berlin, Walter de Gruyter
    • Krudieck CL, Eto I: Folate in tissues and cells: Support for a 'two tier' hypothesis of one carbon metabolism; in Cooper BA, Whitehead MV (eds): Chemistry and Biology of Pteridines. Berlin, Walter de Gruyter, 1986, pp 447-466.
    • (1986) Chemistry and Biology of Pteridines , pp. 447-466
    • Krudieck, C.L.1    Eto, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.