Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation

Journal of Experimental Medicine

Volumn 203, Issue 4, 2006, Pages 865-870

  Kreisberg, Jason F ^a,b   Yonemoto, Wes ^a   Greene, Warner C ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; IMMUNOSTIMULATING AGENT; INTERLEUKIN 15; INTERLEUKIN 2; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOSTIMULATION; INFECTION SENSITIVITY; LYMPHOID TISSUE; MEMORY T LYMPHOCYTE; MOLECULAR WEIGHT; PRIORITY JOURNAL; VIRUS INHIBITION;

CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HIV INFECTIONS; HUMANS; INTERLEUKIN-15; INTERLEUKIN-2; MOLECULAR WEIGHT; NUCLEOSIDE DEAMINASES; REPRESSOR PROTEINS; TONSIL;

EID: 33645862586     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20051856     Document Type: Article

References (26)

1. Zack, J.A., S.J. Arrigo, S.R. Weitsman, A.S. Go, A. Haislip, and I.S. Chen. 1990. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell. 61:213-222.
2. Stevenson, M., T.L. Stanwick, M.P. Dempsey, and C.A. Lamonica. 1990. HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO J. 9:1551-1560.
3. + T cells residing within human lymphoid tissues. Immunity. 15:671-682.
4. + T cells. Nature. 434:1148-1152.
5. + T cells. Science. 286:1353-1357.
6. + T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques. Proc. Natl. Acad. Sci. USA. 102:8000-8005.
7. + T cell demographics and dynamics in lymphatic tissues. Annu. Rev. Immunol. 17:625-656.
8. + T cells in multiple tissues during acute SIV infection. Nature. 434:1093-1097.
9. Spina, C.A., H.E. Prince, and D.D. Richman. 1997. Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. J. Clin. Invest. 99:1774-1785.
10. + memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc. Natl. Acad. Sci. USA. 87:6058-6062.
11. Roederer, M., P.A. Raju, D.K. Mitra, and L.A. Herzenberg. 1997. HIV does not replicate in naive CD4 T cells stimulated with CD3/CD28. J. Clin. Invest. 99:1555-1564.
12. - resting T cells cannot be infected de novo with HIV-1. Proc. Natl. Acad. Sci. USA. 94:1361-1365.
13. + T cells are infected in human immunodeficiency virus type 1-infected individuals. J. Virol. 73:6430-6435.
14. + T cell decline. Proc. Natl. Acad. Sci. USA. 97:1269-1274.
15. + T cells. Nature. 435:108-114.
16. Audige, A., E. Schlaepfer, A. Bonanomi, H. Joller, M.C. Knuchel, M. Weber, D. Nadal, and R.F. Speck. 2004. HIV-1 does not provoke alteration of cytokine gene expression in lymphoid tissue after acute infection ex vivo. J. Immunol. 172:2687-2696.
17. + T cells: role of lymphoid tissue microenvironment and effect of immunomodulating agents. AIDS Res. Hum. Retroviruses. 19:847-856.
18. Unutmaz, D., V.N. KewalRamani, S. Marmon, and D.R. Littman. 1999. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes. J. Exp. Med. 189:1735-1746.
19. + T-lymphocyte subset. Microbiol. Immunol. 49:155-165.
20. Cavalieri, S., S. Cazzaniga, M. Geuna, Z. Magnani, C. Bordignon, L. Naldini, and C. Bonini. 2003. Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence. Blood. 102:497-505.
21. Swingler, S., B. Brichacek, J.M. Jacque, C. Ulich, J. Zhou, and M. Stevenson. 2003. HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection. Nature. 424:213-219.
22. Kinter, A.L., G. Poli, L. Fox, E. Hardy, and A.S. Fauci. 1995. HIV replication in IL-2-stimulated peripheral blood mononuclear cells is driven in an autocrine/paracrine manner by endogenous cytokines. J. Immunol. 154:2448-2459.
23. + T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokines and the viral inductive effects of other endogenous cytokines. Proc. Natl. Acad. Sci. USA. 93:14076-14081.
24. Cavrois, M., C. De Noronha, and W.C. Greene. 2002. A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat. Biotechnol. 20:1151-1154.
25. Hayden, M.S., E.H. Palacios, and R.M. Grant. 2003. Real-time quantitation of HIV-1 p24 and SIV p27 using fluorescence-linked antigen quantification assays. AIDS. 17:629-631.
26. Stopak, K., C. de Noronha, W. Yonemoto, and W.C. Greene. 2003. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol. Cell. 12:591-601.