메뉴 건너뛰기




Volumn 39, Issue 4, 2006, Pages 489-494

Effects of metformin on the glycemic control, lipid profile, and arterial blood pressure of type 2 diabetic patients with metabolic syndrome already on insulin

Author keywords

Blood pressure; Cholesterol; Metabolic syndrome; Metformin; Triglycerides; Type 2 diabetes mellitus

Indexed keywords

CAPTOPRIL; CHOLESTEROL; GEMFIBROZIL; GLUCOSE; HEMOGLOBIN A1C; HYDROCHLOROTHIAZIDE; INSULIN; ISOPHANE INSULIN; METFORMIN; MEVINOLIN; PROPRANOLOL;

EID: 33645823641     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2006000400009     Document Type: Review
Times cited : (20)

References (32)
  • 1
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
    • Stratton IM, Adler AI, Neil HA et al. (2000). Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. British Medical Journal, 321: 405-412.
    • (2000) British Medical Journal , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3
  • 2
    • 0029043874 scopus 로고
    • Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus
    • Krolewski AS, Laffel LM, Krolewski M et al. (1995). Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. New England Journal of Medicine, 332: 1251-1255.
    • (1995) New England Journal of Medicine , vol.332 , pp. 1251-1255
    • Krolewski, A.S.1    Laffel, L.M.2    Krolewski, M.3
  • 3
    • 0032983666 scopus 로고    scopus 로고
    • Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: Progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group
    • Turner RC, Cull CA, Frighi V et al. (1999). Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. Journal of the American Medical Association, 281: 2005-2012.
    • (1999) Journal of the American Medical Association , vol.281 , pp. 2005-2012
    • Turner, R.C.1    Cull, C.A.2    Frighi, V.3
  • 4
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM (1988). Banting lecture 1988. Role of insulin resistance in human disease. Diabetes, 37: 1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 5
    • 0031817898 scopus 로고    scopus 로고
    • Mortality in adults with and without diabetes in a national cohort of the U.S. population, 1971-1993
    • Gu K, Cowie CC & Harris MI (1998). Mortality in adults with and without diabetes in a national cohort of the U.S. population, 1971-1993. Diabetes Care, 21: 1138-1145.
    • (1998) Diabetes Care , vol.21 , pp. 1138-1145
    • Gu, K.1    Cowie, C.C.2    Harris, M.I.3
  • 6
    • 18944387193 scopus 로고    scopus 로고
    • Abdominal obesity and expression of familial combined hyperlipidemia
    • van der Kallen CJ, Voors-Pette C & de Bruin TW (2004). Abdominal obesity and expression of familial combined hyperlipidemia. Obesity Research, 12: 2054-2061.
    • (2004) Obesity Research , vol.12 , pp. 2054-2061
    • van der Kallen, C.J.1    Voors-Pette, C.2    de Bruin, T.W.3
  • 7
    • 0242300702 scopus 로고    scopus 로고
    • The metabolic syndrome as predictor of type 2 diabetes: The San Antonio heart study
    • Lorenzo C, Okoloise M, Williams K et al. (2003). The metabolic syndrome as predictor of type 2 diabetes: the San Antonio heart study. Diabetes Care, 26: 3153-3159.
    • (2003) Diabetes Care , vol.26 , pp. 3153-3159
    • Lorenzo, C.1    Okoloise, M.2    Williams, K.3
  • 8
    • 14644427817 scopus 로고    scopus 로고
    • Impact of waist circumference on the relationship between blood pressure and insulin: The Quebec Health Survey
    • Poirier P, Lemieux I, Mauriege P et al. (2005). Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey. Hypertension, 45: 363-367.
    • (2005) Hypertension , vol.45 , pp. 363-367
    • Poirier, P.1    Lemieux, I.2    Mauriege, P.3
  • 9
    • 18144442252 scopus 로고    scopus 로고
    • Potential contribution of metformin to the management of cardiovascular disease risk in patients with abdominal obesity, the metabolic syndrome and type 2 diabetes
    • Despres JP (2003). Potential contribution of metformin to the management of cardiovascular disease risk in patients with abdominal obesity, the metabolic syndrome and type 2 diabetes. Diabetes and Metabolism, 29:6S53-6S61.
    • (2003) Diabetes and Metabolism , vol.29
    • Despres, J.P.1
  • 10
    • 3042541843 scopus 로고    scopus 로고
    • The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus: A systematic review
    • Wulffele MG, Kooy A, de Zeeuw D et al. (2004). The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus: a systematic review. Journal of Internal Medicine, 256: 1-14.
    • (2004) Journal of Internal Medicine , vol.256 , pp. 1-14
    • Wulffele, M.G.1    Kooy, A.2    de Zeeuw, D.3
  • 11
    • 0036137212 scopus 로고    scopus 로고
    • Insulin-metformin combination therapy in obese patients with type 2 diabetes
    • Jaber LA, Nowak SN & Slaughter RR (2002). Insulin-metformin combination therapy in obese patients with type 2 diabetes. Journal of Clinical Pharmacology, 42: 89-94.
    • (2002) Journal of Clinical Pharmacology , vol.42 , pp. 89-94
    • Jaber, L.A.1    Nowak, S.N.2    Slaughter, R.R.3
  • 12
    • 0036782581 scopus 로고    scopus 로고
    • Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and troglitazone in type 2 diabetes
    • Strowig SM, Viles-Santa ML & Raskin P (2002). Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and troglitazone in type 2 diabetes. Diabetes Care, 25: 1691-1698.
    • (2002) Diabetes Care , vol.25 , pp. 1691-1698
    • Strowig, S.M.1    Viles-Santa, M.L.2    Raskin, P.3
  • 13
    • 0042689028 scopus 로고    scopus 로고
    • Combination of insulin and metformin in the treatment of type 2 diabetes
    • Wulffele MG, Kooy A, Lehert P et al. (2002). Combination of insulin and metformin in the treatment of type 2 diabetes. Diabetes Care, 25: 2133-2140.
    • (2002) Diabetes Care , vol.25 , pp. 2133-2140
    • Wulffele, M.G.1    Kooy, A.2    Lehert, P.3
  • 14
    • 0035897696 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (2001). Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Journal of the American Medical Association, 285: 2486-2497.
    • (2001) Journal of the American Medical Association , vol.285 , pp. 2486-2497
  • 15
    • 17744400090 scopus 로고    scopus 로고
    • Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome
    • Pasquali R, Gambineri A, Biscotti D et al. (2000). Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 85: 2767-2774.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 2767-2774
    • Pasquali, R.1    Gambineri, A.2    Biscotti, D.3
  • 17
    • 0038147377 scopus 로고    scopus 로고
    • Using new insulin strategies in the outpatient treatment of diabetes: Clinical applications
    • DeWitt DE & Dugdale DC (2003). Using new insulin strategies in the outpatient treatment of diabetes: clinical applications. Journal of the American Medical Association, 289: 2265-2269.
    • (2003) Journal of the American Medical Association , vol.289 , pp. 2265-2269
    • DeWitt, D.E.1    Dugdale, D.C.2
  • 18
    • 84910011021 scopus 로고    scopus 로고
    • A review of metabolic and cardiovascular effects of oral antidiabetic agents: Beyond glucose-level lowering
    • Ginsberg H, Plutzky J & Sobel BE (1999). A review of metabolic and cardiovascular effects of oral antidiabetic agents: beyond glucose-level lowering. Journal of Cardiovascular Risk, 6: 337-346.
    • (1999) Journal of Cardiovascular Risk , vol.6 , pp. 337-346
    • Ginsberg, H.1    Plutzky, J.2    Sobel, B.E.3
  • 19
    • 0030022720 scopus 로고    scopus 로고
    • The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type II diabetes
    • Grant PJ (1996). The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type II diabetes. Diabetes Care, 19: 64-66.
    • (1996) Diabetes Care , vol.19 , pp. 64-66
    • Grant, P.J.1
  • 20
    • 0343724362 scopus 로고    scopus 로고
    • Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus. A randomized, controlled trial
    • Yki-Jarvinen H, Ryysy L, Nikkila K et al. (1999). Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus. A randomized, controlled trial. Annals of Internal Medicine, 130: 389-396.
    • (1999) Annals of Internal Medicine , vol.130 , pp. 389-396
    • Yki-Jarvinen, H.1    Ryysy, L.2    Nikkila, K.3
  • 21
    • 0031767174 scopus 로고    scopus 로고
    • The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control
    • Robinson AC, Burke J, Robinson S et al. (1998). The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control. Diabetes Care, 21: 701-705.
    • (1998) Diabetes Care , vol.21 , pp. 701-705
    • Robinson, A.C.1    Burke, J.2    Robinson, S.3
  • 22
    • 0024342099 scopus 로고
    • Different effects of insulin and oral anticliabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus
    • Groop L, Widen E, Franssila-Kallunki A et al. (1989). Different effects of insulin and oral anticliabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia, 32: 599-605.
    • (1989) Diabetologia , vol.32 , pp. 599-605
    • Groop, L.1    Widen, E.2    Franssila-Kallunki, A.3
  • 23
    • 0023755090 scopus 로고
    • The effect of glibenclamide and metformin on serum lipoproteins in type 2 diabetes
    • Rains SG, Wilson GA, Richmond W et al. (1988). The effect of glibenclamide and metformin on serum lipoproteins in type 2 diabetes. Diabetic Medicine, 5: 653-658.
    • (1988) Diabetic Medicine , vol.5 , pp. 653-658
    • Rains, S.G.1    Wilson, G.A.2    Richmond, W.3
  • 24
    • 0029099086 scopus 로고
    • Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus
    • The Multi-center Metformin Study Group
    • DeFronzo RA & Goodman AM (1995). Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multi-center Metformin Study Group. New England Journal of Medicine, 333: 541-549.
    • (1995) New England Journal of Medicine , vol.333 , pp. 541-549
    • DeFronzo, R.A.1    Goodman, A.M.2
  • 25
    • 0027399661 scopus 로고
    • Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups
    • Nagi DK & Yudkin JS (1993). Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups. Diabetes Care, 16: 621-629.
    • (1993) Diabetes Care , vol.16 , pp. 621-629
    • Nagi, D.K.1    Yudkin, J.S.2
  • 26
    • 0027411979 scopus 로고
    • Metformin for obese, insulin-treated diabetic patients: Improvement in glycaemic control and reduction of metabolic risk factors
    • Giugliano D, Quatraro A, Consoli G et al. (1993). Metformin for obese, insulin-treated diabetic patients: improvement in glycaemic control and reduction of metabolic risk factors. European Journal of Clinical Pharmacology, 44: 107-112.
    • (1993) European Journal of Clinical Pharmacology , vol.44 , pp. 107-112
    • Giugliano, D.1    Quatraro, A.2    Consoli, G.3
  • 27
    • 0026029277 scopus 로고
    • Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
    • Landin K, Tengborn L & Smith U (1991). Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors. Journal of Internal Medicine, 229: 181-187.
    • (1991) Journal of Internal Medicine , vol.229 , pp. 181-187
    • Landin, K.1    Tengborn, L.2    Smith, U.3
  • 29
    • 0019424146 scopus 로고
    • The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients
    • Tuck ML, Sowers J, Dornfeld L et al. (1981). The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients. New England Journal of Medicine, 304: 930-933.
    • (1981) New England Journal of Medicine , vol.304 , pp. 930-933
    • Tuck, M.L.1    Sowers, J.2    Dornfeld, L.3
  • 30
    • 12144259447 scopus 로고    scopus 로고
    • Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes
    • Katakami N, Yamasaki Y, Hayaishi-Okano R et al. (2004). Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. Diabetologia, 47: 1906-1913.
    • (2004) Diabetologia , vol.47 , pp. 1906-1913
    • Katakami, N.1    Yamasaki, Y.2    Hayaishi-Okano, R.3
  • 31
    • 18144449351 scopus 로고    scopus 로고
    • Do effects on blood pressure contribute to improved clinical outcomes with metformin?
    • Schafers RF (2003). Do effects on blood pressure contribute to improved clinical outcomes with metformin? Diabetes and Metabolism, 29: 6S62-6S70.
    • (2003) Diabetes and Metabolism , vol.29
    • Schafers, R.F.1
  • 32
    • 9244220688 scopus 로고    scopus 로고
    • Effects of metformin treatment on luteal phase progesterone concentration in polycystic ovary syndrome
    • Meenakumari KJ, Agarwal S, Krishna A et al. (2004). Effects of metformin treatment on luteal phase progesterone concentration in polycystic ovary syndrome. Brazilian Journal of Medical and Biological Research, 37: 1637-1644.
    • (2004) Brazilian Journal of Medical and Biological Research , vol.37 , pp. 1637-1644
    • Meenakumari, K.J.1    Agarwal, S.2    Krishna, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.