Utility of molecular genetic signatures in the delineation of gastric neoplasia

Cancer

Volumn 106, Issue 7, 2006, Pages 1480-1488

  Kidd, Mark ^a   Modlin, Irvin M ^a   Mane, Shrikant M ^a   Camp, Robert L ^a   Eick, Geeta N ^a   Latich, Igor ^a   Zikusoka, Michelle N ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AQUA; Carcinoid; Gastric; Invasive phenotype; Malignancy; PCR; Tissue microarray

Indexed keywords

CHROMOGRANIN A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; RNA;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER STAGING; CARCINOID; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAGE D2 GENE; MALE; MICROARRAY ANALYSIS; MOLECULAR GENETICS; MTA1 GENE; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; STOMACH ADENOCARCINOMA; STOMACH TUMOR; STROMA CELL;

ADENOCARCINOMA; ADULT; AGED; ANTIGENS, NEOPLASM; CARCINOID TUMOR; CHROMOGRANIN A; CHROMOGRANINS; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENE EXPRESSION PROFILING; GENETIC MARKERS; HISTONE DEACETYLASES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 33645821907     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.21758     Document Type: Article

References (39)

1. Modlin IM, Kidd M, Latich I, Zikusoka MN, Shapiro MD. Current status of gastrointestinal carcinoids. Gastroenterology. 2005;128:1717-1751.
2. Modlin IM, Lye KD, Kidd M. Carcinoid tumors of the stomach. Surg Oncol. 2003;12:153-172.
3. Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understanding of their biology. Hum Pathol. 1999;30:1213-1220.
4. Wong WM, Wright NA. Cell proliferation in gastrointestinal mucosa. J Clin Pathol. 1999;52:321-333.
5. Abdalla EK, Pisters PW. Staging and preoperative evaluation of upper gastrointestinal malignancies. Semin Oncol. 2004;31:513-529.
6. Greene FL. TNM staging for malignancies of the digestive tract: 2003 changes and beyond. Semin Surg Oncol. 2003;21:23-29.
7. Boussioutas A, Taupin D. Towards a molecular approach to gastric cancer management. Intern Med J. 2001;31:296-303.
8. Becker KF, Keller G, Hoefler H. The use of molecular biology in diagnosis and prognosis of gastric cancer. Surg Oncol. 2000;9:5-11.
9. Meireles SI, Cristo EB, Carvalho AF, et al. Molecular classifiers for gastric cancer and nonmalignant diseases of the gastric mucosa. Cancer Res. 2004;64:1255-1265.
10. Kidd M, Shapiro M, Mane S, Modlin I. The utility of AP-1 gene analysis of human gastric ECL cell carcinoid tumors to define gastrin-autonomy and determine tumor subtypes. Gastroenterology. 2004;126:M992.
11. Waldum HL, Aase S, Kvetnoi I, et al. Neuroendocrine differentiation in human gastric carcinoma. Cancer. 1998;83:435-444.
12. Kidd M, Modlin IM, Mane SM, Camp RL, Eick G, Latich I. The role of genetic markers, NAP1L1, MAGE-D2 and MTA1, in defining small intestinal carcinoid neoplasia. Ann Surg Oncol. 2006;13:253-262.
13. Ardill JE, Erikkson B. The importance of the measurement of circulating markers in patients with neuroendocrine tumours of the pancreas and gut. Endocr Relat Cancer. 2003;10:459-462. Review.
14. Li M, Lin YM, Hasegawa S, et al. Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray. Int J Oncol. 2004;24:305-312.
15. Toh Y, Oki E, Oda S, et al. Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis. Int J Cancer. 1997;74:459-463.
16. Hofer MD, Kuefer R, Varambally S, et al. The role of metastasis- associated protein 1 in prostate cancer progression. Cancer Res. 2004;64:825-829.
17. Moon WS, Chang K, Tarnawski AS. Overexpression of metastatic tumor antigen 1 in hepatocellular carcinoma: relationship to vascular invasion and estrogen receptor-alpha. Hum Pathol 2004;35:424-429.
18. Toh Y, Ohga T, Endo K, et al. Expression of the metastasis-associated MTA1 protein and its relationship to deacetylation of the histone H4 in esophageal squamous cell carcinomas. Int J Cancer. 2004;110:362-367.
19. Toh Y, Pencil SD, Nicolson GL. Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines. Gene. 1995;159:97-104.
20. Toh Y, Pencil SD, Nicolson GL. A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. J Biol Chem. 1994;269:22958-22963.
21. Heinrich M, Corless C. Gastric GI stromal tumors (GISTs): the role of surgery in the era of targeted therapy. J Surg Oncol. 2005;90:195-207.
22. Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med. 2002;8:1323-1327.
23. Xie W, Mertens J, Reiss D, et al. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. Cancer Res. 2002;62:497-505.
24. Camp R, Charette L, Rimm D. Validation of tissue microarray technology in breast carcinoma. Lab Invest. 2000;80:1943-1949.
25. Kidd M, Eick G, Shapiro MD, et al. Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors. Cancer. 2005;103:229-236.
26. Hofer MD, Menke A, Genze F, Gierschik P, Giehl K. Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells. Br J Cancer. 2004;90:455-462.
27. Sundaresan V, Reeve JG, Stenning S, Stewart S, Bleehen NM. Neuroendocrine differentiation and clinical behaviour in non-small cell lung tumours. Br J Cancer. 1991;64:333-338.
28. Scopsi L, Andreola S, Pilotti S, et al. Argyrophilia and granin (chromogranin/secretogranin) expression in female breast carcinomas. Their relationship to survival and other disease parameters. Am J Surg Pathol. 1992;16:561-576.
29. di Sant'Agnese PA. Neuroendocrine differentiation in carcinoma of the prostate. Diagnostic, prognostic, and therapeutic implications. Cancer. 1992;70:254-268.
30. de Bruine AP, Wiggers T, Beek C, et al. Endocrine cells in colorectal adenocarcinomas: incidence, hormone profile and prognostic relevance. Int J Cancer. 1993;54:765-771.
31. Pour PM, Permert J, Mogaki M, Fujii H, Kazakoff K. Endocrine aspects of exocrine cancer of the pancreas. Their patterns and suggested biologic significance. Am J Clin Pathol 1993;100:223-230.
32. Tarle M, Frkovic-Grazio S, Kraljic I, Kovacic K. A more objective staging of advanced prostate cancer-routine recognition of malignant endocrine structures: the assessment of serum TPS, PSA, and NSE values. Prostate. 1994;24:143-148.
33. Eren F, Celikel C, Gulluoglu B. Neuroendocrine differentiation in gastric adenocarcinomas; correlation with tumor stage and expression of VEGF and p53. Pathol Oncol Res. 2004;10:47-51.
34. Tornoczky T, Kover E, Pajor L. Frequent occurrence of low grade cases among metastatic gastrointestinal stromal tumours. J Clin Pathol. 2003;56:363-367.
35. Lucas S, Brasseur F, Boon T. A new MAGE gene with ubiquitous expression does not code for known MAGE antigens recognized by T cells. Cancer Res. 1999;59:4100-4103.
36. Langnaese K, Moos DU, Wehnert M, Seidel B, Wieacker P. Expression pattern and further characterization of human MAGED2 and identification of rodent orthologues. Cytogenet Cell Genet. 2001;94:233-240.
37. Nicolson GL, Nawa A, Toh Y, et al. Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation. Clin Exp Metastasis. 2003;20:19-24.
38. Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer. 2003;97:934-959.
39. Connolly EM, Gaffney E, Reynolds IV. Gastrointestinal stromal tumours. Br J Surg. 2003;90:1178-1186.