메뉴 건너뛰기




Volumn 17, Issue SUPPL. 2, 2006, Pages

Multi-target inhibitors in non-small cell lung cancer (NSCLC)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CETUXIMAB; DOCETAXEL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; ERLOTINIB; GEFITINIB; PACLITAXEL; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SORAFENIB; STEM CELL FACTOR RECEPTOR; SUNITINIB; VANDETANIB; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 33645812143     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdj924     Document Type: Article
Times cited : (9)

References (23)
  • 2
    • 0037050355 scopus 로고    scopus 로고
    • Lung cancer-time to move on from chemotherapy
    • Carney DN. Lung cancer-time to move on from chemotherapy. N Engl J Med 2002; 346: 126-128.
    • (2002) N Engl J Med , vol.346 , pp. 126-128
    • Carney, D.N.1
  • 3
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Sheperd FA, Rodrigues Pereira J, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-132.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Sheperd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 4
    • 22144471081 scopus 로고    scopus 로고
    • Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) trial - E4599
    • (Abstr no. 4)
    • Sandler AB, Gray R, Brahmer J et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): an Eastern Cooperative Oncology Group (ECOG) trial - E4599. J Clin Oncol 2005, 23: 2s (Abstr no. 4).
    • (2005) J Clin Oncol , vol.23
    • Sandler, A.B.1    Gray, R.2    Brahmer, J.3
  • 5
    • 1642442499 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors: A new prospective in the treatment of lung cancer
    • Tiseo M, Loprevite M, Ardizzoni A. Epidermal growth factor receptor inhibitors: A new prospective in the treatment of lung cancer. Curr Med Chem Anti-Canc Agents 2004; 4 (2): 139-148.
    • (2004) Curr Med Chem Anti-Canc Agents , vol.4 , Issue.2 , pp. 139-148
    • Tiseo, M.1    Loprevite, M.2    Ardizzoni, A.3
  • 6
    • 19844375720 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small cell lung cancer: Implications for treatment and tumor biology
    • Janne PA, Engelman JA and Johnson BE. Epidermal growth factor receptor mutations in non-small cell lung cancer: Implications for treatment and tumor biology. J Clin Oncol 2005; 23: 3227-3234.
    • (2005) J Clin Oncol , vol.23 , pp. 3227-3234
    • Janne, P.A.1    Engelman, J.A.2    Johnson, B.E.3
  • 7
    • 20244381389 scopus 로고    scopus 로고
    • Phase I/II trial evaluating the antivascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/Epidermal Growth Factor Receptor tyrosine kinase inhibitor erlotinib for patients with recurrent Non-Small-Cell Lung Cancer
    • Herbst RS, Johnson DH, Mininberg E et al. Phase I/II trial evaluating the antivascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/Epidermal Growth Factor Receptor tyrosine kinase inhibitor erlotinib for patients with recurrent Non-Small-Cell Lung Cancer. J Clin Oncol 2005, 23: 2544-2555.
    • (2005) J Clin Oncol , vol.23 , pp. 2544-2555
    • Herbst, R.S.1    Johnson, D.H.2    Mininberg, E.3
  • 8
    • 21244457921 scopus 로고    scopus 로고
    • Role of novel targeted therapies in the clinic
    • Herbst RS. Role of novel targeted therapies in the clinic. Br J Cancer 2005; 92 (Suppl 1): S21-S27.
    • (2005) Br J Cancer , vol.92 , Issue.SUPPL. 1
    • Herbst, R.S.1
  • 9
    • 21244475061 scopus 로고    scopus 로고
    • ZD6474 - A novel inhibitor of VEGFR and EGFR tyrosine kinase activity
    • Ryan AJ, Wedge SR. ZD6474 - a novel inhibitor of VEGFR and EGFR tyrosine kinase activity. Br J Cancer 2005; 92 (Suppl 1): S7-S13.
    • (2005) Br J Cancer , vol.92 , Issue.SUPPL. 1
    • Ryan, A.J.1    Wedge, S.R.2
  • 10
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signalling, angiogenesis, and tumor growth following oral administration
    • Wedge SR, Ogilvie DJ, Dukes M et al. ZD6474 inhibits vascular endothelial growth factor signalling, angiogenesis, and tumor growth following oral administration. Cancer Res 2002; 62: 4645-4655.
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3
  • 11
    • 0037386774 scopus 로고    scopus 로고
    • Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase
    • Ciardiello F, Caputo R, Damiano V et al. Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase. Clin Cancer Res 2003; 9: 1546-1556.
    • (2003) Clin Cancer Res , vol.9 , pp. 1546-1556
    • Ciardiello, F.1    Caputo, R.2    Damiano, V.3
  • 12
    • 0842289982 scopus 로고    scopus 로고
    • Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy
    • Ciardiello F, Bianco R, Caputo R et al. Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. Clin Cancer Res 2004; 10: 784-793.
    • (2004) Clin Cancer Res , vol.10 , pp. 784-793
    • Ciardiello, F.1    Bianco, R.2    Caputo, R.3
  • 13
    • 21244488907 scopus 로고    scopus 로고
    • ZD6474 - Clinical experience to date
    • Heymach JV. ZD6474 - clinical experience to date. Br J Cancer 2005; 92 (Suppl 1): S14-S20.
    • (2005) Br J Cancer , vol.92 , Issue.SUPPL. 1
    • Heymach, J.V.1
  • 14
    • 28444488046 scopus 로고    scopus 로고
    • A comparison of the antitumour efficacy of ZD6474 and gefitinib (Iressa™) in patients with NSCLC: Results of a randomized, double blind phase II study
    • (Abstr O-103)
    • Natale R, Bodkin D, Govindan R et al. A comparison of the antitumour efficacy of ZD6474 and gefitinib (Iressa™) in patients with NSCLC: results of a randomized, double blind phase II study. Lung Cancer 2005; 49 (Suppl 2): S37 (Abstr O-103).
    • (2005) Lung Cancer , vol.49 , Issue.SUPPL. 2
    • Natale, R.1    Bodkin, D.2    Govindan, R.3
  • 15
    • 28444452328 scopus 로고    scopus 로고
    • ZD6474 in combination with carboplatin and paclitaxel as first-line treatment in patients with NSCLC: Results of the run-in phase of a two-part randomized phase II study
    • (Abstr. P-497)
    • Heymach J, West H, Kerr R et al. ZD6474 in combination with carboplatin and paclitaxel as first-line treatment in patients with NSCLC: Results of the run-in phase of a two-part randomized phase II study. Lung Cancer 2005; 49 (Suppl 2): S247 (Abstr. P-497).
    • (2005) Lung Cancer , vol.49 , Issue.SUPPL. 2
    • Heymach, J.1    West, H.2    Kerr, R.3
  • 16
    • 28444474907 scopus 로고    scopus 로고
    • ZD6474 plus docetaxel with previously treated NSCLC: Results of a randomized, placebo-controlled phase II trial
    • (Abstr. O-100)
    • Herbst RS, Johnson B, Rowbottom J et al. ZD6474 plus docetaxel with previously treated NSCLC: Results of a randomized, placebo-controlled phase II trial. Lung Cancer 2005; 49 (Suppl 2): S35 (Abstr. O-100).
    • (2005) Lung Cancer , vol.49 , Issue.SUPPL. 2
    • Herbst, R.S.1    Johnson, B.2    Rowbottom, J.3
  • 17
    • 78650874372 scopus 로고    scopus 로고
    • SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
    • Abrams TJ, Lee LB, Murray LJ et al. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003; 2: 471-478.
    • (2003) Mol Cancer Ther , vol.2 , pp. 471-478
    • Abrams, T.J.1    Lee, L.B.2    Murray, L.J.3
  • 18
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • Mendel DB, Laird AD, Xin X et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003; 9: 327-337.
    • (2003) Clin Cancer Res , vol.9 , pp. 327-337
    • Mendel, D.B.1    Laird, A.D.2    Xin, X.3
  • 19
    • 33644847440 scopus 로고    scopus 로고
    • Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
    • (Published ahead of print on November 28, 2005 as 10.1200/JCO.2005.02.2194.)
    • Faivre S, Delbaldo C, Vera K et al. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 2006; (Published ahead of print on November 28, 2005 as 10.1200/JCO.2005.02.2194.)
    • (2006) J Clin Oncol
    • Faivre, S.1    Delbaldo, C.2    Vera, K.3
  • 20
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases Involved in tumor progression and angiogenesis
    • Wilhelm SM, Carter C, Tang L et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases Involved in tumor progression and angiogenesis. Cancer Res 2004; 64: 7099-7109.
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 21
    • 23044510046 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY43-9006, in patients with advanced, refractory solid tumors
    • Clark JW, Eder JP, Ryan D et al. Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY43-9006, in patients with advanced, refractory solid tumors. Clin Cancer Res 2005; 11: 5472-5480.
    • (2005) Clin Cancer Res , vol.11 , pp. 5472-5480
    • Clark, J.W.1    Eder, J.P.2    Ryan, D.3
  • 22
    • 20044382799 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
    • Strumberg D, Richly H, Hilger RA et al. Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 2005; 23: 965-972.
    • (2005) J Clin Oncol , vol.23 , pp. 965-972
    • Strumberg, D.1    Richly, H.2    Hilger, R.A.3
  • 23
    • 28044434570 scopus 로고    scopus 로고
    • A Phase I study of BAY 43-9006 and gefitinib in patients with refractory or recurrent non-small-cell lung cancer (NSCLC)
    • (Abstr. 3067)
    • Adjei AA, Mandrekar S, Marks RS et al. A Phase I study of BAY 43-9006 and gefitinib in patients with refractory or recurrent non-small-cell lung cancer (NSCLC). J Clin Oncol 2005; 23: 208S (Abstr. 3067).
    • (2005) J Clin Oncol , vol.23
    • Adjei, A.A.1    Mandrekar, S.2    Marks, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.