TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 4, 2006, Pages

  Rao, Jaladanki N ^a,b   Platoshyn, Oleksandr ^c   Golovina, Vera A ^a   Liu, Lan ^a,b   Zou, Tongtong ^a,b   Marasa, Bernard S ^a,b   Turner, Douglas J ^a   Yuan, Jason X J ^c   Wang, Jian Ying ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Ca2+ influx; Canonical transient receptor potential 1; Intracellular Ca2+; Mucosal injury; Polyamines; Rapid mucosal repair; Voltage gated K + channels

Indexed keywords

CALCIUM CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; WOUND;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE; EPITHELIAL CELLS; INTESTINAL MUCOSA; ION CHANNEL GATING; RATS; TRPC CATION CHANNELS; WOUND HEALING;

EID: 33645802398     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00441.2005     Document Type: Article

References (57)

1. 2+ signaling in arterial myocytes. Am J Physiol Cell Physiol 278: C163-C173, 2000.
2. Berridge MJ, Lipp P, and Bootman MD. The calcium entry pas de deux. Science 287: 1604-1605, 2000.
3. Birnbaumer L, Zhu X, Jiang M, Boulay G, Peyton M, Vannier B, Brown D, Platano D, Sadeghi H, Stefani E, and Birnbaumer M. On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. Proc Natl Acad Sci USA 93: 15195-15202, 1996.
4. 2+ store and cell responsiveness. Am J Physiol Cell Physiol 264: C1367-C1387, 1993.
5. Bootman MD. The elemental principles of calcium signaling. Cell 83: 675-678, 1995.
6. 2+-signals. J Cell Sci 114: 213-222, 2001.
7. Clapham DE, Runnels LW, and Strubing C. The TRP ion channel family. Nature Rev Neurosci 2: 387-396, 2001.
8. Clapham DE. TRP channels as cellular sensors. Nature 426: 517-524, 2003.
9. Fleischman BK, Washabau RJ, and Kotlikoff MI. Control of resting membrane potential by delayed rectifier potassium currents in ferret airway smooth muscle cells. J Physiol 469: 625-638, 1993.
10. 2+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 280: H746-H755, 2001.
11. 2+ during intestinal epithelial cell migration. Am J Physiol Cell Physiol 283: C722-C735, 2002.
12. Guo X, Rao JN, Liu L, Zuo TT, Turner DJ, and Wang JY. Regulation of adherens junctions and epithelial paracellular permeability: novel function for polyamines. Am J Physiol Cell Physiol 285: C1174-C1187, 2003.
13. Harter JL. Critical values for Duncan's new multiple range test. Biometrics 16: 671-685, 1960.
14. Himmel HA, Whorton AR, and Strauss HC. Intracellular calcium, currents, and stimulus-response coupling in endothelial cells. Hypertension 21: 112-117, 1993.
15. Kerschbaum HH and Cahalan MD. Monovalent permeability, rectifi-cation, and ionic block of store-operated calcium channels in Jurkat T lymphocytes. J Gen Physiol 111: 521-537, 1998.
16. 2+ channel in Jurkat T lymphocytes. Science 283: 836-839, 1999.
17. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1990.
18. 2+ influx mechanism in salivary gland cells. J Biol Chem 275: 3403-3411, 2000.
19. 2+ channels: role of acidic amino acid residues in the S5-S6 region. J Biol Chem 278: 11337-11343, 2003.
20. Liu L, Li L, Rao JN, Zou T, Zhang HM, Boneva D, Bernard MS, and Wang JY. Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation. Am J Physiol Cell Physiol 288: C89-C99, 2005.
21. McCormack SA, Viar MJ, and Johnson LR. Polyamines are necessary for cell migration by a small intestinal crypt cell line. Am J Physiol Gastrointest Liver Physiol 264: G367-G374, 1993.
22. 2+ entry in agonist-induced pulmonary vasoconstriction. Am J Physiol Lung Cell Mol Physiol 280: L870-L880, 2001.
23. Minke B and Cook B. TRP channels and signal transduction. Physiol Rev 82: 429-472, 2002.
24. Montell C and Rubin GM. Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2: 1313-1323, 1989.
25. Moore TM, Brough GH, Babal P, and Stevens T. Store-operated calcium entry promotes shape change in pulmonary endothelial cells expressing Trp1. Am J Physiol Lung Cell Mol Physiol 275: L574-L582, 1998.
26. Nilius B, Viana F, and Droogmans G. Ion channels in vascular endothelium. Annu Rev Physiol 59: 145-170, 1997.
27. Nusrat A, Delp C, and Madara JL. Intestinal epithelial restitution: characterization of cell culture model and mapping of cytoskeletal elements in migrating cells. J Clin Invest 89: 1501-1511, 1992.
28. Okada T, Inoue R, Yamazaki K, Maeda A, Kurosaki T, Yamakuni T, Tanaka I, Shimizu S, Ikenaka K, Imoto K, and Mori Y. Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. J Biol Chem 274: 27359-27370, 1999.
29. Parekh AB and Penner R. Store depletion and calcium influx. Physiol Rev 77: 901-930, 1997.
30. Phillip S, Cavalie A, Freichel M, and Flockerzi. A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL. EMBO J 15: 6166-6171, 1996.
31. Phillips AM, Bull A, and Kelly LE. Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene. Neuron 8: 631-642, 1992.
32. Quaroni A, Wands J, Trelstat RL, and Isselbacher KJ. Epithelial cell cultures from rat small intestine. J Cell Biol 80: 248-265, 1979.
33. Rao JN, Li L, Li J, Bass BL, and Wang JY. Differentiated intestinal epithelial cells exhibit increased migration through polyamines and myosin II. Am J Physiol Gastrointest Liver Physiol 277: G1149-G1158, 1999.
34. 2+-RhoA signaling pathway required for polyamine-dependent intestinal epithelial cell migration. Am J Physiol Cell Physiol 280: C993-C1007, 2001.
35. + channels and increased migration of differentiated intestinal epithelial cells after wounding. Am J Physiol Cell Physiol 282: C885-C898, 2002.
36. 2+ signaling in epithelial restitution. In: Gastrointestinal Mucosal Repair and Experimental Therapeutics, edited by Cho CH and Wang JY. Basel, Switzerland: Karger, 2002, vol. 25, p. 29-42.
37. Rao JN, Guo X, Liu L, Zou T, Murthy KS, Yuan JXY, and Wang JY. Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. Am J Physiol Cell Physiol 284: C848-C859, 2003.
38. 2+ entry and intestinal epithelial cell migration during restitution (Abstract). Gastroenterology 125: A537, 2004.
39. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Borisy G, Parson JT, and Horwitz AR. Cell migration: integrating signals from front to back. Science 302: 1704-1709, 2003.
40. Rutten MJ and Ito S. Morphology and electrophysiology of guinea pig gastric mucosal repair in vitro. Am J Physiol Gastrointest Liver Physiol 244: G171-G182, 1983.
41. Santos MF, McCormack SA, Guo Z, Okolicany J, and Johnson LR. Rho proteins play a critical role in cell migration during the early phases of mucosal restitution. J Clin Invest 100: 216-225, 1997.
42. Sharp PA. RNA interference-2001. Genes Dev 15: 485-490, 2001.
43. Silen W and Ito S. Mechanism for rapid-epithelialization of the gastric mucosal surface. Annu Rev Physiol 47: 217-229, 1985.
44. Suh E and Traber PG. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol Cell Biol 16: 619-625, 1996.
45. 2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 283: L144-L155, 2002.
46. Tsien RW and Tsien RY. Calcium channels, stores, and oscillations. Annu Rev Cell Biol 6: 715-760, 1990.
47. Wang J, Laurier LG, Sims SM, and Preiksaitis HG. Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle. Am J Physiol Gastrointest Liver Physiol 284: G1074-G1083, 2003.
48. Wang JY and Johnson LR. Luminal polyamines stimulate repair of gastric mucosal stress ulcers. Am J Physiol Gastrointest Liver Physiol 259: G584-G592, 1990.
49. Wang JY, McCormack SA, Viar MJ, Wang HL, Tzen CY, Scott RE, and Johnson LR. Decreased expression of protooncogenes c-fos, c-myc, and c-jun following polyamine depletion in IEC-6 cells. Am J Physiol Gastrointest Liver Physiol 265: G331-G338, 1993.
50. + channel expression in polyamine-dependent intestinal epithelial cell migration. Am J Physiol Cell Physiol 278: C303-C314, 2000.
51. Wes PD, Chevesich J, Jeromin A, Rosenberg C, and Stetten G. TRPC1, a human homolog of a Drosophila store-operated channel. Proc Natl Acad Sci USA 92: 9652-9656, 1995.
52. Xu XZ, Chien F, Butler A, Salkoff L, and Montel C. TRPγ, a Drosophila TRP-related subunit, forms a regulated cation channel with TRPL. Neuron 26: 647-657, 2000.
53. 2+ channels in native vascular smooth muscle cells. Circ Res 88: 84-87, 2001.
54. 2+ entry. Cell 85: 661-671, 1996.
55. Zhu X and Birnbaumer L. Calcium channels formed by mammalian trp homologues. News Physiol Sci 13: 211-217, 1998.
56. Zitt C and Schultz G. Expression of TRPC3 in Chinese hamster ovary cells results in calcium activated cation currents not related to store depletion. J Cell Biol 138: 1333-1341, 1997.
57. Zitt C, Halaszovich CR, and Luckhoff A. The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry. Prog Neurobiol 66:243-264, 2003.