Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells

Journal of Hepatology

Volumn 44, Issue 5, 2006, Pages 869-878

  Naka, Kazuhito ^a   Abe, Ken ichi ^a   Takemoto, Kazunori ^a   Dansako, Hiromichi ^a   Ikeda, Masanori ^a   Shimotohno, Kunitada ^b   Kato, Nobuyuki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

cDNA microarray; DNA methylation; Epigenetic silencing; HCV replicon; IFN resistance

Indexed keywords

ALPHA INTERFERON; AZACITIDINE; COMPLEMENTARY DNA;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DEMETHYLATION; DNA DETERMINATION; DNA METHYLATION; DNA MICROARRAY; EPIGENETICS; FUNCTIONAL ASSESSMENT; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE IDENTIFICATION; GENE INDUCTION; GENE SILENCING; HEPATITIS C VIRUS; MOLECULAR MECHANICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPLICON; UPREGULATION; VIRUS RESISTANCE;

ANTIVIRAL AGENTS; AZACITIDINE; CELLS, CULTURED; DNA METHYLATION; DRUG RESISTANCE, VIRAL; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, VIRAL; GENE SILENCING; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REPLICON; UP-REGULATION;

EID: 33645797382     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.01.030     Document Type: Article

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