The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking

Biochemical Journal

Volumn 395, Issue 2, 2006, Pages 239-247

  Dukes, Joseph D ^a   Lee, Huailo ^a   Hagen, Rachel ^a   Reaves, Barbara J ^a   Layton, Abigail N ^b   Galyov, Edouard E ^b   Whitley, Paul ^a  

^a University of Bath   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

Endosomal sorting complexes required for transport (ESCRT); Endosome; Lysosome trafficking; PtdIns(3,5)P2; Salmonella dublin; SopB

Indexed keywords

CELL CULTURE; ENZYME KINETICS; FUNCTIONS; LIPIDS;

ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT (ESCRT); ENDOSOME; LYSOSOME TRAFFICKING; PTDINS(3,5)P2; SALMONELLA DUBLIN;

PROTEINS;

EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATASE; PHOSPHOINOSITIDE PHOSPHATASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CELL SURFACE RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; POLYPHOSPHOINOSITIDE; SOPB PROTEIN, SALMONELLA;

ANIMAL CELL; ARTICLE; CELL MATURATION; CELL TRANSPORT; CELLULAR DISTRIBUTION; ENDOSOME; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VIVO STUDY; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SALMONELLA DUBLIN; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL STRAIN COS1; CERCOPITHECUS; ENZYMOLOGY; GENE EXPRESSION; HELA CELL; KINETICS; METABOLISM; PROTEIN TRANSPORT; SALMONELLA; SECRETION;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR DUBLIN;

ANIMALS; BACTERIAL PROTEINS; CELL MEMBRANE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOSOMES; GENE EXPRESSION; HELA CELLS; HUMANS; KINETICS; LYSOSOMES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN TRANSPORT; RECEPTORS, CELL SURFACE; SALMONELLA;

EID: 33645792576     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20051451     Document Type: Article

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