Brucella spp noncanonical LPS: Structure, biosynthesis, and interaction with host immune system

Microbial Cell Factories

Volumn 5, Issue , 2006, Pages

  Cardoso, Patrícia Gomes ^a   Macedo, Gilson Costa ^a   Azevedo, Vasco ^a   Oliveira, Sergio Costa ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CATION; PEPTIDE;

ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BRUCELLA; BRUCELLOSIS; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CLASSIFICATION; GENUS; HOST; HUMAN; IMMUNE SYSTEM; INNATE IMMUNITY; MOLECULAR INTERACTION; NONHUMAN; PHAGOCYTE; REVIEW; VETERINARY ABORTION;

ANIMALIA; BACTERIA (MICROORGANISMS); BRUCELLA; BRUCELLA MELITENSIS;

EID: 33645765569     PISSN: 14752859     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-5-13     Document Type: Review

References (58)

1. Young EJ: An overview of human brucellosis. Clin Infect Dis 1995, 21:283-289.
2. Corbel MJ, Brinley-Morgan WJ: Genus Brucella. In Bergey's Manual of Systematic Bacteriology Volume I. Edited by: Krieg NR, Holt JG. The Williams & Wilkins, Baltimore; 1984:377-388.
3. Blasco JM: Brucella ovis. In Animal brucellosis Edited by: Nielsen K, Duncan JR. Boca Raton, FL: CRC Press; 1990:351-78.
4. Davis DS: Brucellosis in Wildlife. In Animal Brucellosis Edited by: Nielsen K, Duncan JR. CRC Press, Boca Raton, FL; 1990:321-334.
5. Cloeckaert A, Verger JM, Grayon M, Paquet JY, Garin-Bastuji B, Foster G, Godfroid J: Classification of Brucella spp. isolated from marine mammals by DNA polymorphism at the omp2 locus. Microbes Infect 2001, 3:729-738.
6. Cloeckaert A, Grayon M, Greépinet 0, Boumedine KS: Classification of Brucella strains isolated from marine mammals by infrequent restriction site-PCR and development of specific PCR identification tests. Microbes Infect 2003, 5:593-602.
7. Alton GG, Jones LM, Angus RD, Verger JM: Techniques for the Brucellosis Laboratory. Institut National de la Recherche Agronomique, Paris 1988.
8. Guihot A, Bossi P, Bricaire F: Bioterrorism with brucellosis. Presse Med 2004, 33:119-22.
9. Lapaque N, Moriyon I, Moreno E, Gorvel JP: Brucella lipolysaccharide acts as a virulence factor. Current Opinion in Microbiology 2005, 8:60-66.
10. Bundle DR, Cherwonogrodzky JW, Gidney MAJ, Meikle PJ, Perry MB, Peters T: Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharicles. Infect Immun 1989, 57:2829-2836.
11. Moreno E, Stackebrandt E, Dorsch M, Wolters J, Busch M, Mayer H: Brucella abortus 16S rRNA and lipid A reveal phylogenetic relationship with members of the alpha-2 subdivision of the class Proteobacteria. J Bacterial 1990, 172:3569-3576.
12. Raetz CRH: Bacterial lipopolysaccharicles: a remarkable family of bioactive macroamphiphiles. In Escherichia coli and Salmonella Volume 1. Edited by: Neidhardt FC. Cellular and Molecular Biology-, 1996:1035-1063.
13. Ramos-Sánchez MC, Orduña-Domingo A, Rodriguez Tones A, Martin-Gil FJ, Martin-Gi J: Investigations on thermotropic phase behavior of lipids A from Brucella and other Gram-negative bacteria. Thermochim Acta 1992, 144:299-305.
14. Rojas N, Freer E, Weintreub A, Ramfrez M, Lind S, Moreno E: Immunochemical identification of Brucella abortus lipopolysaccharide epitopes. Clin Diagn Lab Immunol 1994, 1:206-213.
15. Freer E, Rojas N, Weintraub A, Lindberg AA, Moreno E: Heterogeneity of Brucella abortus lipopolysaccharides. Res Microbial 1995, 146:569-578.
16. Raetz CR: Biochemistry of endotoxins. Annu Rev Biochem 1990, 59:129-170.
17. Díaz-Aparicio E, Aragón V, Marín C, Alonso B, Font M, Moreno E, Pérez-Ortiz S, Blasco JM, Diaz R, Moriyón I: Comparative analysis of Brucella serotypes A and M and Yersinia enterocolitica O:9 polysaccharides for serological diagnosis of brucellosis in cattle, sheep, and goats. J Clin Microbiol 1993, 31:3136-3141.
18. DelVecchio VG, Kapatral V, Redkar RJ, Patra G, Mujer C, Los T, Ivanova N, Anderson I, Bhattacharyya A, Lykidis A, Reznik G, Jablonski L, Larsen N, D'Sousa M, Bernal A, Mazur M, Goltsman E, Selkov E, Elzer PH, Hagius S, O'Callaghan D, Letesson JJ, Haselkorn R, Kyrpides N, Overbeek R: The genome sequence of the facultative intracellular pathogen Brucella melitensis. Proc Natl Acad Sci U S A 2002, 99:443-448.
19. Paulsen IT, Seshadri R, Nelson KE, Eisen JA, Heidelberg JF, Read TD, Dodson RJ, Umayam L, Brinkac LM, Beanan MJ, Daugherty SC, Deboy RT, Durkin AS, Kolonay JF, Madupu R, Nelson WC, Ayodeji B, Kraul M, Shetty J, Malek J, Van Aken SE, Riedmuller S, Tettelin H, Gill SR, White 0, Salzberg SL, Hoover DL, Lindler LE, Halling SM, Boyle SM, Fraser CM: The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts. Proc Natl Acad Sci USA 2002, 99:13148-13153.
20. Halling SM, Peterson-Burch BD, Bricker BJ, Zuerner RL, Qing Z, Li LL, Kapur V, Alt DP, Olsen SC: Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis. J Bacteriol 2005, 8:2715-2726.
21. DelVecchio VG, Kapatral V, Elzer P, Patra G, Mujer CV: The genome of Brucella melitensis. Vet Microbiol 2002, 90:587-592.
22. Dricot A, Rual JF, Lamesch P, Bertin N, et al.: Generation of the Brucella melitensis ORFeome Version I.I. Genome Research 2004, 14:2201-2206.
23. Delrue RM,Lestrate P,Tibor A, Letesson JJ, De Bolle X: Brucella pathogenesis, genes identified from random large-scale screens. FEMS Microbial Lett 2004, 231:1-12.
24. Vizcaino N, Cloeckaert A, Zygmunt MS, Fernandez-Lago L: Characterization of a Brucella species 25-kilobase DNA fragment delected from Brucella abortus reveals a large gene cluster related to the synthesis of a polysaccharide. Infect Immun 2001, 69:6738-6748.
25. Riley LK, Robertson DC: Brucellacidal activity of human and bovine polymorphonuclear leukocyte granule extracts against smooth and rough strains of Brucello obortus. Infect Immun 1984, 46:231-236.
26. Schurig GG, Roop RM, Bagchi T, Boyle S, Buhrman D, Sriranganathan N: Biological properties of RBS 1; a stable rough strain of Bru- cello abortus. Vet Microbial 1991, 28:171-188.
27. Allen CA, Adams LG, Ficht TA: Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival. Infect Immun 1998, 66:1008-1016.
28. Winter AJ, Schurig GG, Boyle SM, Sriranganathan NJ, Bevins S, Enright FM, Elzer PH, Kope JD: Protection of BALB/c mice against homologous and heterologous species of Brucella by rough strain vaccines derived from Brucella melitensis and Brucella suis biovar 4. Am J Vet Res 1996, 57:677-683.
29. Stevens MG, Olsen SC, Pugh GW Jr, Brees D: Comparison of immune responses and resistance to brucellosis in mice vaccinated with Brucella abortus 19 and RB51. Infect Immun 1995, 63:264-270.
30. Godfroid F, Taminiau B, Danese I, Denoel P, Tibor A, Weynants V, Cloeckaert A, Godfroid J, Letesson JJ: Identification of the perosamine synthetase gene of Brucella melitensis 16 M and involvement of lipopolysaccharide O side chain in Brucella survival in mice and in macrophages. Infect Immun 1998, 66:5485-5493.
31. Stroeher UH, Karageorgos LE, Brown MH, Morona R, Manning PA: A putative pathway for perosamine biosynthesis is the first function encoded within the rfb region of Vibrio cholleroe OI. Gene 1995, 166:33-42.
32. Zygmunt MS, Dubray G, Bundle DR, Perry MP: Purified native haptens of Brucella abortus B19 and B. melitensis 16 M reveal the lipopolysaccharicle origin of the antigens. Ann Inst Pasteur Micro- biol 1988, 139:421-433.
33. Hong PC, Tsolis RM, Ficht TA: Identification of genes required for chronic persistence of Brucella abortus in mice. Infect Immun 2000, 68:4102-4107.
34. Kido N, Ohta M, Iida KI, Hasegawa T, Ito H, Arakawa Y, Komatsu T, Kato N: Partial deletion of the cloned rfb gene of Escherichia coli O9 results in synthesis of a new O-antigenic lipopolysaccharide. J Bacteriol 1989, 171:3629-3633.
35. McQuiston JR, Vemulapalli R, Inzana TJ, Schurig GG, Sriranganathan N, Fritzinger D, Hadfield TL, Warren RA, Snellings N, Hoover D, Halling S, Boyle SM: Genetic Characterization of a Tn 5-Disrupted glycosyltransferase gene homolog in Brucella abortus and its effect on lipopolysaccharide composition and virulence. Infect Immun 1999, 99:3830-3835.
36. Vemulapalli R, McQuiston JR, Schurig GG, Sriranganathan N, Halling SM, Boyle SM: Identification of an IS711 element interrupting the wboA gene of Brucella abortus vaccine strain RB51 and a PCR assay to distinguish strain RB51 from other Brucella species and strains. Clin Diagn Lab Immunol 1999, 5:760-764.
37. Vemulapalli R, He Y, Buccolo LS, Boyle SM, Sriranganathan N, Schurig GG: Complementation of Brucella abortus RB51 with a functional wboA gene results in O-antigen synthesis and enhanced vaccine efficacy but no change in rough phenotype and attenuation. Infect Immun 2000, 7:3927-3932.
38. Fernandez-Prada CM, Nikolich M, Vemulapalli R, Sriranganathan N, Boyle SM, Schurig GG, Hadfield TL, Hoover DL: Deletion of wboA enhances activation of the lectin pathway of complement in Brucella abortus and Brucella melitensis. Infect Immun 2001, 7:4407-4416.
39. Fernandez-Prada CM, Zelazowska EB, Nikolich M, Hadfield TL, Roop RM 2nd, Robertson GL, Hoover DL: Interactions between Brucella melitensis and human phagocytes: bacterial surface O-polysaccharide inhibits phagocytosis, bacterial killing, and subsequent host cell apoptosis. Infect Immun 2003, 71:2110-9.
40. Vizcaino N, Caro-Hernandez P, Cloeckaert A, Fernandez-Lago L: DNA polymorphism in the omp25/omp31 family of Brucella spp.: identification of a 1.7-kb inversion in Brucella cetaceae and of a I5.1-kb genomic island, absent from Brucella ovis, related to the synthesis of smooth lipopolysaccharide. Microbes Infect 2004, 6:821-834.
41. Ugalde JE, Czibener C, Feldman MF, Ugalde RA: Identification and characterization of the Brucella ob ortus phosphoglucomutase gene: role of lipopolysaccharide in virulence and intracellular multiplication. Infect Immun 2000, 68:5719-5723.
42. Ugalde JE, Comerci DJ, Leguizamon MS, Ugalde RA: Evaluation of Brucella obortus phosphoglucomutase (pgm) mutant as a new live rough-phenotype vaccine. Infect Immun 2003, 71:6264-9.
43. Godfroid F, Cloeckaert A, Taminiau B, Danese I, Tibor A, De Bolle X, Mertens P, Letesson JJ: Genetic organization of the lipopolysaccharide O-antigen biosynthesis region of Brucella melitensis 16 M (wbk). Res Microbiol 2000, 151:655-668.
44. Reeves PR, Hobbs M, Valvano MA, Skurnik M, Whitfield C, Coplin D, Kido D, Klena NJ, Maskel D, Raetz CRH, Rick PD: Bacterial polysaccharide synthesis and gene nomenclature. Trends Microbiol 1996, 4:495-503.
45. Cloeckaert A, Grayon M, Verger JM, Letesson JJ, Godfroid F: Conservation of seven genes involved in the biosynthesis of the lipopolysaccharide O-side chain in Brucella spp. Res Microbiol 2000, 151:209-16.
46. Monreal D, Grillo MJ, Gonzalez D, Marin CM, De Miguel MJ, Lopez- Goni I, Blasco JM, Cloeckaert A, Moriyon I: Characterization of Brucella abortus O-polysaccharide and core lipopolysaccharide mutants and demonstration that a complete core is required for rough vaccines to be efficient against Brucella abortus and Brucella ovis in the mouse model. Infect Immun 2003, 6:3261-71.
47. Sola-Landa A, Pizarro-Cerdo J, Grilló MJ, Moreno E, Morrión I, Blasco IM, Gorvel JP, López-Goñi I: A two-component regulatory system playing a critical role in plant pathogen and endosymbionts is present in Brucella abortus and controls cell invasion and virulence. Mol Microbiol 1998, 29:125-138.
48. Finlay B, Falkow S: Common themes in microbial pathogenicity. Microbiol Mol Rev 1997, 61:136-169.
49. Pizarro-Cerda J, Meresse S, Parton RG, van der Goot G, Sola-Landa A, Lopez-Goni I, Moreno E, Gorvel JP: Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes. Infect Immun 1998, 66:5711-5724.
50. Pizarro-Cerda J, Moreno E, Sanguedolce V, Mege ]L, Gorvel JP: Virulent Brucella abortus prevents lysosome fusion and is distributed within autophagosome-like compartments. Infect Immun 1998, 66:2387-2392.
51. Dorn BR, Dunn WA Jr, Progulske-Fox A: Bacterial interactions with the autophagic pathway. Cell Mkrobiol 2002, 4:1-10.
52. Porte F, Naroeni A, Ouahrani-Bettache S, Liautard JP. Role of the Brucella suis lipopolysaccharide O antigen in phagosomal genesis and in inhibition of phagosome-lysosome fusion in murine macrophages. Infect Immun 2003, 71:1481-1490.
53. Erridge C, Bennett-Guerrero E, Poxton IR: Structure and function of lipopolysaccharides. Microbes and Infection 2002, 4:837-851.
54. Zaitseva M, Golding H, Manischewitz J, Webb D, Golding B: Brucella obortus as a potential vaccine candidate: induction of interleukin- 12 secretion and enhanced B7.1 and B7.2 and intercellular adhesion molecule I surface expression in elutriated human monocytes stimulated by heat-inactivated B. abortus. Infect Immun 1996, 64:3109-3119.
55. Campos MA, Rosinha GM, Almeida IC, Salgueiro XS, Jarvis BW, Splitter GA, Qureshi N, Bruna-Romero O, Gazzinelli RT, Oliveira SC: Role of Toll-Like Receptor 4 in Induction of Cell-Mediated Immunity and Resistance to Brucella abortus Infection in Mice. Infect Immun 2004, 1:176-186.
56. Glambartolomei GH, Zwerdling A, Cassataro J, Bruno L, Fossati CA, Philipp MT: Lipoprotein, not lypopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed Brucella abortus. J Immunol 2004, 173:463S-4642.
57. Weiss DS, Takeda K, Akira S, Zychlinskii A, Moreno E: MyD88, but not toll-like receptors 4 and 2, is required for efficient clearance of Brucella abortus. Infect Immun 200S, 73:5137-5143.
58. Huang L, Ishii KJ, Akira S, Aliberti J, Golding B: Th I-like cytokine induction by heat-killed Brucelia abortus is dependent on triggering of TLR9. J Immunol 2005, 175:3964-3970.