Increased migration of vascular adventitial fibroblasts from spontaneously hypertensive rats

Hypertension Research

Volumn 29, Issue 2, 2006, Pages 95-103

  Li, Li ^a,b,c   Zhu, Ding Liang ^a,b,c   Shen, Wei Li ^a,b,c   Gao, Ping Jin ^a,b,c  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Shanghai Institute of Hypertension   (China)

Author keywords

Angiotensin II; Extracellular regulated protein kinase; Migration; p38 mitogen activated protein kinase; Vascular adventitial fibroblast

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; BASIC FIBROBLAST GROWTH FACTOR; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHORBOL ESTER; PLATELET DERIVED GROWTH FACTOR BB;

ADVENTITIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INJURY; CELL MIGRATION; CELL STIMULATION; CONCENTRATION RESPONSE; DRUG METABOLISM; ENZYME PHOSPHORYLATION; FIBROBLAST; HYPERTENSION; MALE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; THORACIC AORTA;

ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; CELL MOVEMENT; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HYPERTENSION; MALE; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION;

EID: 33645761635     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.29.95     Document Type: Article

References (23)

1. Shi Y, O'Brien JE, Fard A, Mannion JD, Wang D, Zalewski A: Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 1996; 94: 1655-1664.
2. Sartore, S, Chiavegato A, Faggin E, et al: Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: From innocent bystander to active participant. Circ Res 2001; 89: 1111-1121.
3. Wilcox JN, Scott NA: Potential role of the adventitia in arteritis and atherosclerosis. Int J Cardiol 1996; 54 (Suppl): S21-S35.
4. Li G, Chen SJ, Oparil S, Chen YF, Thompson JA: Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries. Circulation 2000; 101: 1362-1365.
5. Siow RC, Mallawaarachchi CM, Weissberg PL: Migration of adventitial myofibroblasts following vascular balloon injury: insights from in vivo gene transfer to rat carotid arteries. Cardiovasc Res 2003; 59: 212-221.
6. Zhu DL, Herembert T, Marche P: Increased proliferation of adventitial fibroblasts from spontaneously hypertensive rat aorta. J Hypertens 1991; 9: 1161-1168.
7. Hsieh CC, Lau Y: Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat. Pflügers Arch 1998; 435: 286-292.
8. Gao PJ, Li Y, Sun AJ, et al: Differentiation of vascular myofibroblasts induced by transforming growth factor-beta 1 requires the involvement of protein kinase C alpha. J Mol Cell Cardiol 2003; 35: 1105-1112.
9. + (I(A)) channels in rat vascular myofibroblasts. Biochem Biophys Res Commun 2003; 301: 17-23.
10. Fishel RS, Thourani V, Eisenberg SJ, et al: Fibroblast growth factor stimulate angiotensin converting enzyme expression in vascular smooth muscle cells. J Clin Invest 1995; 95: 377-387.
11. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
12. Miura S, Saku K, Karnik SS: Molecular analysis of the structure and function of the angiotensin II type 1 receptor. Hypertens Res 2003; 26: 937-943.
13. Kubo M, Umemoto S, Fujii K, et al: Effects of angiotensin II type 1 receptor antagonist on smooth muscle cell pheno-type in intramyocardial arteries from spontaneously hypertensive rats. Hypertens Res 2004; 27: 685-693.
14. Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ: Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation 1996; 94: 2756-2767.
15. Egido J: Vasoactive hormones and renal sclerosis. Kidney Int 1996; 49: 578-597.
16. Antus B, Mucsi I, Rosivall L: Apoptosis induction and inhibition of cellular proliferation by angiotensin II: Possible implication and perspectives. Acta Physiol Hung 2000; 87: 5-24.
17. Rogerson FM, Chai SY, Schlawe I, Murray WK, Marley PD, Mendelsohn FA: Presence of angiotensin converting enzyme in the adventitial of large blood vessels. J Hypertens 1992; 10: 615-620.
18. Tsunemi K, Takai S, Nishimoto M, et al: Possible roles of angiotensin II-forming enzymes, angiotensin converting enzyme and chymase-like enzyme, in the human aneurysmal aorta. Hypertens Res 2002; 25: 817-822.
19. Wolf G, Wenzel UO: Angiotensin II and cell cycle regulation. Hypertension 2004; 43: 693-698.
20. 2-terminal kinase activation. Mol Pharmacol 2004; 65: 832-841.
21. 1, integrin expression in the rat carotid artery: Involvement in smooth muscle cell migration and neointima formation. Cardiovasc Res 2005; 65: 813-822.
22. Miller FJ Jr: Adventitial fibroblasts: Backstage journeymen. Arterioscler Thromb Vasc Biol 2001; 21: 722-723.
23. Shen WL, Gao PJ, Che ZQ, et al: NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation. Biochem Biophys Res Commun 2006; 339: 337-343.