Vasoactive hormones and renal sclerosis

Kidney International

Volumn 49, Issue 2, 1996, Pages 578-597

  Egido, Jesús ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Division of Nephrology and Hypertension   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; HORMONE; HYDROCHLOROTHIAZIDE; NIFEDIPINE; VASOACTIVE AGENT;

ADULT; CASE REPORT; CONFERENCE PAPER; GLOMERULONEPHRITIS; HEMATURIA; HUMAN; HYPERTENSION; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY FAILURE; KIDNEY SCLEROSIS; MALE; PRIORITY JOURNAL; PROTEINURIA;

EID: 0030031995     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.82     Document Type: Conference Paper

References (229)

1. REMUZZI A, PERTICUCCI A, RUGGENENTI P, MOSCONI L, LIMONTA M, REMUZZI G: Angiotensin converting enzyme inhibition improves glomerular size-selectivity in IgA nephropathy. Kidney Int 39:1267-1273, 1991
2. COPPO R, AMORE A, GIANOGLIO B, CACACE G, PICCIOTTO G, ROCCATELLO D, PERUZZI L, PICCOLI G, DE FILIPPE. PG: Angiotensin II local hyperreactivity in the progression of IgA nephropathy. Am J Kidney Dis 21:593-602, 1993
3. CATTRAN DC, GREENWOOD C, RITCHIE S: Long-term benefits of angiotensin-converting enzyme inhibitor therapy in patients with severe immunoglobulin A nephropathy: A comparison to patients receiving treatment with other antihypertensive agents and to patients receiving no therapy. Am J Kidney Dis 23: 247-254, 1994
4. TER WEE PM, EPSTEIN M: Angiotensin-converting enzyme inhibitors and progression of nondiabetic chronic renal disease. Arch Intern Med 153:1749-1759, 1993
5. HOLLENBERG NK, RAIJ L: Angiotensin-converting enzyme inhibition and renal protection. As assessment of implications for therapy. Arch Intern Med 153:2426-2435, 1993
6. LEWIS EJ, HUNSICKER LG, BAIN RP, ROHDE RA: The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 329:1456-1462, 1993
7. ICHIKAWA I, HARRIS RC: Angiotensin actions in the kidney: renewed insight into the old hormone. Kidney Int 40:583-596, 1991
8. MIMRAN A, INSUA A, RIBSTEIN J, BRINGER J, MONNIER L: Comparative effect of captopril and nifedipine in normotensive patients with incipient diabetic nephropathy. Diabetes Care 11:850-853, 1988
9. WOLF G, NEILSON EG: Angiotensin II as a renal growth factor. J Am Soc Neprol 3:1531-1540, 1993
10. DZAU VJ: Cell biology and genetics of angiotensin in cardiovascular disease. J Hypertens 12 (suppl 4):S3-S10, 1994
11. MULROW PJ: The intrarenal renin-angiotensin system. Curr Opin Nephrol Hypertens 2:41-44, 1993
12. DZAU VJ, MUKOYAMA M, PRATT RE: Molecular biology of angiotensin receptors: target for drug research? J Hypertens 12 (suppl 2):S1-S5, 1994
13. YANAGISAWA M, KURIHARA H, KIMURA S: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415, 1993
14. SIMONSON MS: Endothelins: Multifunctional renal peptides. Physiol Rev 73:375-411, 1993
15. SIMONSON MS, DUNN MJ: Endothelin peptides: A possible role in glomerular inflammation. Lab Invest 64:1-4, 1991
16. PERICO N, REMUZZI G: Role of endothelin in glomerular injury. Kidney Int 43 (suppl 39): S76-S80, 1993
17. SEIKALY MG, ARANI BS, SENEY FD: Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. J Clin Invest 86: 1352-1357, 1990
18. PAUL M, WAGNER J, DZAU VJ: Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. J Clin Invest 91:2058-2064, 1993
19. 1 receptors. Kidney Int 45:177-184, 1994
20. STOLL M, STECKFLINGS UM, PAUL M, BOTTARI SP, METZGER R, UNGER T: The angiotensin AT-2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 95: 651-657, 1995
21. JOHNSON MC, AGUILERA G: Angiotensin II receptor subtypes and coupling to signaling systems in cultured fetal fibroblast. Endocrinology 129:1266-1274, 1992
22. MARRERO MB, PAXTON WC, DUFF JL, BERK BC: Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma1 in vascular smooth muscle cells. J Biol Chem 269:10935-10939, 1994
23. MUKOYAMA M, NAKAJIMA M, HORIUCHI M, SASAMURA H, PRATT RE, DZAU VJ: Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J Biol Chem 268: 24539-24542, 1993
24. MARX M, STERZEL B, SOROKIN L: Renal matrix and adhesion in injury and inflammation. Curr Opin Nephrol Hypertens 2:527-535, 1993
25. NAFTILAN AJ, PRATT RE, DZAU VJ: Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. J Clin Invest 83:1419-1424, 1989
26. GRIFFIN SA, BROWN WCB, MACPHERSON F, MCGRATH J, WILSON VG, KORSGAARD N, MULVANY MJ, LEVER AF: Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Hypertension 17:626-635, 1991
27. 1 expression determines growth response to angiotensin II. J Clin Invest 90:456-461, 1992
28. ITOH H, MUKOYAMA M, PRATT RE, GIBBONS GH, DZAU VJ: Multiple growth factors modulate vascular smooth muscle cell growth response to angitensin II. J Clin Invest 91:2268-2274, 1993
29. CAMPBELL-BOSWELL M, ROBERTSON AL: Effects of angiotensin II and vasopressin on human smooth muscle cells in vitro. Exp Mol Pathol 35:265-276, 1981
30. GEISTERFER AAT, PEACH MJ, OWENS GK: Angiotensin II induces hypertrophy not hyperplasia of cultured rat aortic smooth muscle cells. Circ Res 62:749-756, 1988
31. KAGAMI S, BORDER WA, MILLER DE, NOBLE NA: Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-β expression in rat glomerular mesangial cells. J Clin Invest 93:2431-2437, 1994
32. STOUFFER GA, OWENS GK: TGF-β promotes proliferation of cultured SMC via both PDGF-AA-dependent and PDGF-AA-independent mechanisms. J Clin Invest 93:2048-2055, 1994
33. SUDHIR K, WILSON E, CHATTERJEE K, IVES HE: Mechanical strain and collagen potentiate mitogenic activity of angiotensin II in rat vascular smooth muscle cells. J Clin Invest 92:3003-3007, 1993
34. RISER BL, CORTES P, ZHAO X, BERNSTEIN J, DUMLER F, NARINS RG: Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat. J Clin Invest 90:1932-1943, 1992
35. HOMMA T, AKAI Y, BURNS KD, HARRIS RC: Activation of S6 kinase by repeated cycles of stretching and relaxation in rat glomerular mesangial cells. J Biol Chem 267:23129-23135, 1992
36. WOLF G, NEILSON EG: Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells. Kidney Int 43:S100-S107, 1993
37. WOLF G, HABERSTROH U, NEILSON EG: Angiotensin II stimulates the proliferation and biosynthesis of type I collagen in cultured mesangial cells. Am J Pathol 140:95-107, 1992
38. ANDERSON PW, DO YS, HSUEH A: Angiotensin II causes mesangial hypertrophy. Hypertension (Dallas) 21:29-35, 1993
39. BAGBY SP, KIRK EA, MUTCHELL LH, O'REILLY MM, HOLDEN WE, STENBERG PE, BAKKE AC: Proliferate synergy of ANG II and EGF in porcine aortic vascular smooth muscle cells. Am J Physiol 265: F239-F249, 1993
40. SALTIS J, AGROTIS A, BOBIK A: Transforming growth factor-beta 1 enhances the proliferate effects of epidermal growth factor on vascular smooth muscle from the spontaneously hypertensive rat. J Hypertens S6:S184-S185, 1991
41. GIBBONS GH, DZAU VJ: The emerging concept of vascular remodeling. N Engl J Med 330:1431-1438, 1994
42. WEBER H, TAYLOR DS, MOLLOY CJ: Angiotensin II induces delayed mitogenesis and cellular proliferation in rat aortic smooth muscle cells. J Clin Invest 93:788-798, 1994
43. RUPPRECHT HD, DANN P, SUKHATME VP, STERZEL RB, COLEMAN DL: Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: correlation with mitogenicity. Am J Physiol 263:F623-F636, 1992
44. ROSENBERG ME, HOSTETTER TH, KREN S, CHMIELEWSKI D: In vivo effect of angiotensin II and norepinephrine on early growth response genes in the rat kidney. Kidney Int 43:601-609, 1993
45. NEYSES LK, NOUSKAS J, LUYKEN J, FRONHOFFS S, OBERDORF S, PFEIFER U, WILLIAMS RS, SUKHATME VP, VETTER H: Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes. J Hypertens 11:927-934, 1993
46. WOLF G, NEILSON EG: Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. Am J Physiol 259:F768-777, 1990
47. 1 receptor. Nephrol Dial Transplant 8:128-133, 1993
48. DONNELLY P, BURNS KD, BENNETT M, PRUDHOMME C, HARRIS RC: Epidermal growth factor (EGF) and angiotensin II (AH) stimulate S6 kinase activity and protein synthesis in cultured rabbit proximal tubule cells (abstract). J Am Soc Nephrol 1:468, 1990
49. NORMAN J, BADIE-DEZFOOLY B, NORD EP, KURTZ I, SCHLOSSER J, CHAUDHARI A, FINE LG: EGF-induced mitogenesis in proximal tubular cells: potentiation by angiotensin II. Am J Physiol 253:F299-F307, 1987
50. RUIZ-ORTEGA M, GÓMEZ-GARRE D, PALACIOS I, BUSTOS C, GONZÁLEZ E, EGIDO J: Effect of angiotensin II and endothelin on matrix protein synthesis by cultured mesangial cells. A complicated network of interactions (abstract). J Am Soc Nephrol 4:664, 1993
51. RUIZ-ORTEGA M, GOMEZ-GARRE D, ALCAZAR R, PALACIOS I, BUSTOS C, GONZALEZ S, PLAZA JJ, GONZALEZ E, EGIDO J: Involvement of angiotensin II and endothelin in matrix protein production and renal sclerosis. J Hypertens 12:S51-S58, 1994
52. SIMON G, ABRAHAM G, ALTMAN S: Stimulation of vascular glycosaminoglycan synthesis by subpressor doses of Angiotensin II in rats. Hypertension 23 (suppl I):148-151, 1994
53. BORDER WA, RUOSLAHTI E: Transforming growth factor-β in disease: The dark side of tissue repair. J Clin Invest 90:1-7, 1992
54. OKUDA S, LANGIUINO LR, RUOSLAHTI E, BORDER WA: Elevated expression of transforming growth factor-Beta and proteoglycan production in experimental glomerulonephritis. J Clin Invest 86:453-462, 1990
55. YAMAMOTO T, NOBLE NA, MILLER DE, BORDER WA: Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis. Kidney Int 45:916-927, 1994
56. ISAKA Y, FUJIWARA Y, UEDA N, KANEDA Y, KAMADA T, IMAI E: Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth gene into the rat kidney. J Clin Invest 92:2597-2601, 1993
57. LOPEZ-ARMADA MJ, GÓMEZ-GUERRERO C, GONZÁLEZ E, EGIDO J: Immune complexes stimulate the expression and synthesis of matrix proteins in cultured rat and human mesangial cells. Role of transforming growth factor β (abstract). J Am Soc Nephrol 25:812, 1994
58. RUIZ-ORTEGA M, LARGO R, BUSTOS C, GOMEZ-GARRE D, PLAZA JJ, GONZALEZ E, EGIDO J: Platelet activating factor (PAF) stimulates the expression and synthesis of extracellular matrix proteins in cultured renal cells (abstract). J Am Soc Nephrol 25:683, 1994
59. BRUNNER HR: Nephrology Forum: ACE inhibitors in renal disease. Kidney Int 42:463-479, 1992
60. SHINAMURA T, MORRISON AB: A progressive glomerulosclerosis occurring in five-sixths nephrectomized rats. Am J Pathol 79:95-101, 1971
61. HOSTETTER TH, OLSON JL, RENNKE HG, VENKATACHALAM MA, BRENNER BM: Hyperfiltration in remmant nephrons: a potentially adverse response to renal ablation. Am J Physiol 241:F85-F93, 1981
62. ANDERSON S, RENNKE HG, BRENNER BM: Therapeutic advantages of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 77:1993-2000, 1986
63. RAIJ L, CHIOU X, OWENS R, WRIGLEY B: Therapeutic implications of hypertension induced glomerular injury. Comparison of enalapril and a combination of hydralazine, reserpine and hydrochlorothiazide in an experimental model. Am J Med 79(suppl 3C):37-41, 1985
64. DWORKIN LD, GROSSER M, FEINER HD, ULLIAN M, PARKER M: Renal vascular effects of antihypertensive therapy in uninephrectomized SHR. Kidney Int 35: 790-798, 1989
65. KIYAMA S, NANISHI F, TOMOOKA S, OKUDA S, ONOYAMA K, FUJISHIMA M: Inhibitory effects of antihypertensive drugs on mesangial cell proliferation after anti-thymocyte serum (ATS)-induced mesangiolysis in spontaneously hypertensive rats. Life Sci 54:1891-1900, 1994
66. SANCHEZ CRESPO M, ALONSO F, BARAT A, EGIDO J: Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane. Clin Exp Immunol 49:631-638, 1982
67. RUIZ ORTEGA M, GONZALEZ S, SERON D, CONDOM E, BUSTOS C, LARGO L, GONZALEZ E, ORTIZ A, EGIDO J: ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix production in a normotensive rat model of immune complex nephritis. Kidney Int 48:1778-1791, 1995
68. JONG PE, HEEG JE, APPERLOO AJ, ZEEUW D: Angiotensin-I converting enzyme inhibition: clinical effects in chronic renal disease. Am J Kidney Dis 17 (suppl 1):85-88, 1991
69. RODICIO JL, ALCAZAR JM, RUILOPE LM: Influence of converting enzyme inhibition on glomerular filtration rate and proteinuria. Kidney Int 38: 590-594, 1990
70. GANSEVOORT RT, DE ZEEUW D, JONG PE: Long-term benefits of the antiproteinuric effect of angiotensin-converting enzyme inhibition in nondiabetic renal disease. Am J Kidney Dis 22:202-206, 1993
71. PRAGA M, HERNANDEZ E, MONTOYO C, ANDRES A, RUILOPE LM, RODICIO JL: Long-term beneficial effects of angiotensin-converting enzyme inhibition in patients with nephrotic proteinuria. Am J Kidney Dis 20: 240-248, 1992
72. PRAGA M, BORSTEIN B, ANDRES A, ARENAS J, OLIET A, MONTOYO C, RUILOPE LM, RODICIO JL: Nephrotic proteinuria without hypoalbuminemia: clinical characteristics and response to angiotensin-converting enzyme inhibition. Am J Kidney Dis 17:330-338, 1991
73. MOGENSEN CE: Long term antihypertensive treatment inhibiting progression of diabetic nephropathy. Br Med J 285:685-688, 1982
74. PARVING HH, ANDERSOEN AR, SMIDT UM, SVENDSEN PA: Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy. Lancet 1:1175-1179, 1983
75. TAGUMA Y, KITAMOTO Y, FUTAKI G: Effect of captopril on heavy proteinuria in azotemic diabetics. N Engl J Med 313:1617-1620, 1985
76. BURNIER M, WAEBER B, BRUNNER HR: The advantages of angiotensin II antagonism. J Hypertens 12:S7-S15, 1994
77. LAFAYETTE RA, MAYER G, PARK SK, MEYER TW: Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest 90:766-771, 1992
78. POLLOCK DM, DIVISH BJ, POLAKOWSKI JS, OPGENORTH TJ: Angiotensin II receptor blockade improves renal function in rats with reduced renal mass. J Pharmacol Exp Ther 267:657-663, 1993
79. GANSEVOORT RT, ZEEUW D, JONG PE: Is the antiproteinuric effect of ACE inhibition mediated by interference in the renin-angiotensin system? Kidney Int 45:861-867, 1994
80. MEYER TAW, ANDERSON S, RENNKE HG, BRENNER BM: Reversing glomerular hypertension stabilizes established glomerular injury. Kidney Int 31:752-759, 1987
81. SAVAGE S, SCHRIER RW: Progressive renal insufficiency: The role of angiotensin converting enzyme inhibitors. Adv Intern Med 37:85-101, 1992
82. MORELLI E, LOON N, MEYER TW, PETERS W, MYERS BD: Effects of converting-enzyme inhibition on barrier function in diabetic glomerulopathy. Diabetes 39:76-82, 1990
83. JOHNSON RJ, ALPERS CE, YOSHIMURA A, LOMBARDI D, PRITZL P, FLOEGE J, SCHWARTZ SM: Renal injury from angiotensin II-mediated hypertension. Hypertension 19:464-474, 1992
84. MAI M, GEIGER H, HILGERS KF, VEELKEN R, MANN JFE, DÄMMRICH J, LUFT FC: Early interstitial changes in hypertension-induced renal injury. Hypertension 22: 754-765, 1993
85. YAMAMOTO Y, YAMAGUCHI T, SHIMAMURA M, HAZATO T: Angiotensin III is a new chemoattractant for polymorphonuclear leukocytes. Biochem Biophys Res Commun 193:1038-1043, 1993
86. BASCANDS JL, PECHER C, ROUAUD S, EMOND C, TACK JL, BASTIE MJ, BURCH R, REGOLI D, GIROLAMI JP: Evidence for existence of two distinct bradykinin receptors on rat mesangial cells. Am J Physiol 264:F548-F556, 1993
87. GARG UC, HASSID A: Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83:1774-1777, 1989
88. SORBI D, FADLY M, HICKS R, ALEXZANDER S, ARBEIT L: Captopril inhibits the 72 kDa and 92 kDa matrix metalloproteinases. Kidney Int 44:1266-1272, 1993
89. GERALD SK, NEILSON EG, HAVERTY TP: Mechanisms of tubulointerstitial fibrosis. Kidney Int 39:550-556, 1991
90. GIACHELLI CM, PICHLER R, LOMBARDI D, DENHARDT DT, ALPERS CE, SCHWARTZ SM, JOHNSON RJ: Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. Kidney Int 45:515-524, 1994
91. ROSENBERG ME, SMITH LJ, CORREA-ROTTER R, HOSTETTER TH: Paradox of the renin-angiotensin system in chronic renal disease. Kidney Int 45:403-410, 1994
92. FOGO A, YOSHIDA Y, YARED A, ICHIKAWA I: Importance of angiogenic action of angiotensin II in the glomerular growth of maturing kidneys. Kidney Int 38:1068-1074, 1990
93. VILLARREAL FJ, KIM NN, UNGAB GD, PRINTZ MP, DILLMAN WH: Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation 88:2849-2861, 1993
94. SCHORB W, BOOZ GW, DOSTAL DE, CONRAD KM, CHANG KC, BAKER KM: Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts. Circulation Res 72:1245-1254, 1993
95. CRABOS M, ROTH M, HAHN AWA, ERNE P: Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. J Clin Invest 93:2372-2378, 1994
96. RODEMANN HP, MÜLLER GA, KNECHT A, NORMAN JT, FINE LG: Fibroblasts of rabbit kidney in culture. I. Characterization and identification of cell-specific markers. Am J Physiol 261:F283-F291, 1993
97. KLAHR S: New insights into the consequences and mechanisms of renal impairment in obstructive nephropathy. Am J Kidney Dis 18:689-699, 1991
98. KANETO H, MORRISSEY J, KLAHR S: Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation. Kidney Int 44:313-321, 1993
99. SHARMA AK, MAUER SM, KIM Y, MICHAEL AF: Interstitial fibrosis in obstructive nephropathy. Kidney Int 44:774-788, 1993
100. PIMENTEL JL, MARTINEZ-MALDONADO M, WILCOX JN, WANG S, LUO C: Regulation of renin-angiotensin system in unilateral ureteral obstruction. Kidney Int 44:390-400, 1993
101. PIMENTEL JL, WANG S, MARTINEZ-MALDONADO M: Regulation of the renal angiotensin II receptor gene in acute unilateral ureteral obstruction. Kidney Int 45:1614-1621, 1994
102. KANETO H, MORRISSEY J, MCCRACKEN R, REYES A, KLAHR S: Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int 45:1637-1647, 1994
103. DIAMOND JR, ANDERSON S: Irreversible tubulointerstitial damage associated with chronic aminonucleoside nephrosis: amelioration by angiotensin I converting enzyme inhibition. Am J Pathol 137:1323-1331, 1990
104. TAMAKI K, OKUDA S, ANDO T, IWAMOTO T, NAKAYAMA M, FUJISHIMA M: TGFβ1 in glomerulosclerosis and interstitial fibrosis of adriamycin nephropathy. Kidney Int 45:525-536, 1994
105. CLAVELL AL, BURNETT JC: Physiologic and pathophysiologic roles of endothelin in the kidney. Curr Opin Nephrol Hypertens 3:66-72, 1994
106. LÜSCHER TF, OEMAR BS, BOULANGER CM, HAHN AWA: Molecular and cellular biology of endothelin and its receptors: Part I. J Hypertens 11:7-11, 1993
107. MARSEN TA, SCHRAMEK H, DUNN MJ: Renal actions of endothelin: Linking cellular signaling pathways to kidney disease. Kidney Int 45:336-344, 1994
108. MASAKI T, VANE JR, VANHOUTTE PM: V. International Union of Pharmacology nomenclature of endothelin receptors. Pharmacol Rev 46:137-142, 1994
109. UJHE K, TERADA Y, NONGUCHI H, SHINOHARA M, TOMITA K, MARUMO F: Messenger RNA expression and synthesis of endothelin-1 along rat nephron segments. J Clin Invest 90:1043-1048, 1992
110. TERRADA YK, TOMITA K, NONOGUCHI H, MARUMO F: Different localization of two types of endothelin receptor mRNA in microdissected rat nephron segments using reverse transcription and polymerase chain reaction. J Clin Invest 60:107-112, 1992
111. KOHAN DE: Production of endothelin-1 by rat mesangial cells: regulation by tumor necrosis factor. J Lab Clin Med 119:477-484, 1992
112. REBIBOU JM, HE CJ, DELARUE F, PERALDI MN, ADIDA C, RONDEAU E, SRAER JD: Functional endothelin 1 receptors on human glomerular podocytes and mesangial cells. Nephrol Dial Transplant 7:288-292, 1992
113. KOHAN DE: Endothelin production by human inner medullary collecting duct cells. J Am Soc Nephrol 3:1719-1721, 1993
114. ZOJA C, ORISIO S, PERICO N, BENIGNI A, MORIGI M, BENATTI L: Constitutive expression of endothelin gene in cultured human mesangial cells and its modulation by transforming growth factor-β thrombin, and thromboxane A2 analogue. Lab Invest 64:16-20, 1991
115. EHRENREICH H, ANDERSON RW, FOX CH, RIECKMANN P, HOFFMAN GS, TRAVIS WD, COLIGAN JE, KEHRL JH, FAUCI AS: Endothelins, peptides with potent vasoactive properties, are produced by human macrophages. J Exp Med 172:1741-1748, 1990
116. IMAI T, HIRATA Y, EMORI T, MARUMO F: Heparin has an inhibitory effect on endothelin 1 synthesis and release by endothelial cells. Hypertension 21: 353-358, 1993
117. IMAI T, HIRATA Y, EMORI T, YANAGISAWA M, MASAKI T, MARUMO F: Induction of endothelin 1 gene by angiotensin and vasopressin in endothelial cells. Hypertension 19:753-757 1992
118. SIMONSON MS, WANN S, MENE P, DUBYAK MM, KESTER Y, NAKAZATO Y: Endothelin stimulates phospholipase C, Na/H exchange, c-fos expression, and mitogenesis in rat mesangial cells. J Clin Invest 83:708-712, 1989
119. BARD KF, MURRAY JJ, BREYER MD, TAKAHASHI K, INAGAMI T, HARRIS RC: Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. J Clin Invest 83:336-342, 1989
120. B receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells. J Clin Invest 93:556-563, 1994
121. GOMEZ-GARRE D, RUIZ-ORTEGA M, ORTEGA M, LARGO L, GONZALEZ E, EGIDO J: ACE inhibition decreases the endothelin-induced fibronectin synthesis in cultured mesangial cells (abstract). Nephrol Dial Transplant 9:892, 1994
122. MONTERO A, RODRIGUEZ-BARBERO A, LÓPEZ NOVOA JM: A role for platelet-activating factor in endothelin-1 induced rat mesangial cell proliferation. Eur J Pharmacol 243:235-240, 1993
123. ISHIMURA E, SHOUJI S, NISHIZAWA Y, MORII H, KASHGARIAN M: Regulation of mRNA expression for extracellular matrix (ECM) by cultured rat mesangial cells (MCs) (abstract). J Am Soc Nephrol 2:546, 1991
124. HAHN AWA, REGENASS S, KERN F, BÜHLER FR, RESINK TJ: Expression of soluble and insoluble fibronectin in rat aorta: Effects of angiotensin II and endothelin-1. Biochem Biophys Res Commun 192:189-197, 1993
125. LOPEZ-FARRE A, GOMEZ-GARRE D, BERNABEU F, MONTAÑES I, MILLAS I, LOPEZ-NOVOA JM: Renal effects and mesangial cell contraction induced by endothelin are mediated by PAF. Kidney Int 39:624-630, 1991
126. LOPEZ-FARRE A, RIESCO A, MOLITZ M, EGIDO J, CASADO S, HERNANDO L, CARAMELO C: Inhibition by L-arginine of the endothelin-mediated increase in cytosolic calcium in human neutrophils. Biochem Biophys Res Commun 178:884-891, 1991
127. GÓMEZ-GARRE D, GUERRA M, GONZÁLEZ E, LÓPEZ-FARRÉ A, RIESCO A, CARAMELO C, ESCANERO J, EGIDO J: Aggregation of human polymorphonuclear leukocytes by endothelin: role of platelet-activating factor. Eur J Pharmacol 224:167-172, 1992
128. LERMA MA, EDWARDS BS, HALLET JW, HEUBLEIN DM, SANDBERG SM, BURNETT JC JR: Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N Engl J Med 325:997-1001, 1991
129. SAKURAI T, GOTO K: Endothelins. Vascular actions and clinical implications. Drugs 46:795-804, 1993
130. LÓPEZ-FARRE A, RIESCO A, ESPINOSA G, DIGIUNI E, CERNADAS MR, ALVAREZ V, MONTÓN M, RIVAS F, GALLEGO MJ, EGIDO J, CASADO S, CARAMELO C: Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. Circulation 88:1166-1171, 1993
131. KON V, BADR KF: Biological actions and pathophysiological significance of endothelin in the kidney. Kidney Int 40:1-12, 1991
132. NORD EP: Nephrology Forum: Renal actions of endothelin. Kidney Int 44:451-463, 1993
133. BENIGNI A, PERICO N, GASPARI F, ZOJA C, BELLIZI L, GABANELLI M, REMUZZI G: Increased renal endothelin production in rats with reduced renal mass. Am J Physiol 260:F331-F339, 1991
134. ORISIO S, BENIGNI A, BRUZZI I, CORNA D, PERICO N, ZOJA C, BENATTI L, REMUZZI G: Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression. Kidney Int 43: 354-358, 1993
135. BENIGNI A, ZOJA C, CORNA D, ORISIO S, LONGARETTI L, BERTANI T, REMUZZI G: A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. Kidney Int 44:440-444, 1993
136. OSADA S, NAKAMURA T, EBIHARA I, SUZUKI S: Endothelin gene expression in glomeruli and medulla from focal glomerulosclerosis (FSG) (abstract). J Am Soc Nephrol 2:412, 1991
137. NAKAMURA T, EBIHARA I, FUKUI M, OSADA S, TOMINO Y, MASAKI T, GOTO K, FURUICHI Y, KOIDE H: Renal expression of mRNAs for endothelin-1, endothelin-3 and endothelin receptors in NZB/WF1 mice. Renal Physiol Biochem 16:233-243, 1993
138. MARDSEN PA, BRENNER BM: Transcriptional regulation of the endothelin-1 gene by TNFα. Am J Physiol 262:C854-C861, 1992
139. YOSHIMURA A, IWASAKI S, INUI K, IDEURA T, KOSHIKAWA S, YANAGISAWA M, MASAKI T: Endothelin-1 and endothelin B type receptor are induced in mesangial proliferative nephritis in the rat. Kidney Int 48:1290-1297, 1995
140. NAKAMURA T, EBIHARA I, TOMINO Y, KOIDE H: Effect of a specific endothelin A receptor antagonist on murine lupus nephritis. Kidney Int 47:481-489, 1995
141. NAKAMURA T, EBIHARA I, SHIRATO I, FUKUI M, TOMINO Y, KOIDE H: Endothelin-1 mRNA expression by peripheral blood monocytes in IgA nephropathy. Lancet 342:1147-1148, 1993
142. YAMAUCHI T, OHNAKA K, TAKAYANAGI R, UMEDA F, NAWAIA H: Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells. FEBS Lett 267:16-18, 1990
143. INISHI Y, UCHIDA S, KANAME S, OGATA E, KUROKAWA K: High ambient glucose down-regulates endothelin-1 receptors in cultured rat mesangial cells (abstract). J Am Soc Nephrol 2:291, 1991
144. FUKUI M, NAKAMURAT, EBIHARA I, OSADA S, TOMINO Y, MASAKI T, GOTO K, FURUICHI Y, KOIDE H: Gene expression for endothelins and their receptors in glomeruli of diabetic rats. J Lab Clin Med 122:149-156, 1993
145. OHTA K, HIRATA Y, SHICHIRI M, KANNO K, EMORI T, TOMITA K, MARUMO F: Urinary excretion of endothelin-1 in normal subjects and patients with renal disease. Kidney Int 39:307-311, 1991
146. ABASSI ZA, KLEIN H, GOLOMB E, KEISER HR: Urinary endothelin: a possible biological marker of renal damage. Am J Hypertens 6:1046-1054, 1993
147. KOHNO M, HORIO T, IKEDA M, YOKOKAWA K, FUKUI T, YASUNARI K, KURIHARA N, TAKEDA T: Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int 42:860-866, 1992
148. CHUA BHL, CHUA CC, DIGLIO CA, SIU BB: Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells. Biochim Biophys Acta 1178:201-206, 1993
149. WEBB ML, DICKINSON KE, DELANEY CL, LIU ECK, SERAFINO R, COHEN RB, MONSHIZADEGAN H, MORELAND S: The endothelin receptor antagonist, BQ-123 inhibits angiotensin II-induced contractions in rabbit aorta. Biochem Biophys Res Commun 185:887-892, 1992
150. KANNO K, HIRATA Y, TSUJINO M, IMAI T, SCHICHIRT MK, ITO H, MARUMO F: Up-regulation of ETb receptor subtype mRNA by angiotensin II in rat cardiomyocytes. Biochem Biophys Res Commun 194:1282-1287, 1993
151. TAKAGI M, MATSHOKA H, ATARASHI K, YAGI S: Endothelin, a new inhibitor of renin release. Biochem Biophys Res Commun 157:1164-1168, 1988
152. MOE O, TEJEDOR A, CAMPBELL WB, ALPERN RJ, HENRICH WL: Effects of endothelin on in vitro renin secretion. Am J Physiol 260:E251-E525, 1991
153. LIN H, SANGMAL M, SMITH MJ, YOUNG DB: Effect of endothelin-1 on glomerular hydraulic pressure and renin release in dogs. Hypertension 21:845-851, 1993
154. KAWAGUCHI H, SAWA H, YASUDA H: Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol 22:839-842, 1990
155. NEYSES L, NOUSKAS J, OBERDORF S, VETTER H: Action of an ACE inhibitor on myocardial early growth response. J Cardiovasc Pharmacol 20 (suppl B):S12-S14, 1992
156. CHANG DP, CLAVELL A, KEISER J, BURNETT JC: Effects of renin-angiotensin system in mediating endothelin-induced renal vasoconstriction: therapeutic implications. J Hypertens 12:S43-S49, 1994
157. MORTENSEN LH, FINK GD: Captopril prevents chronic hypertension produced by infusion of endothelin-1 in rats. Hypertension 19:676-680, 1992
158. YOSHIDA H, NAKAMURA M: Inhibition by angiotensin converting enzyme inhibitors of endothelin secretion from cultured human endothelial cells. Life Sci 50:195-200, 1992
159. MOMOSE N, FUKUO K, MORIMOTO S, OGIHARA T: Captopril inhibits endothelin-1 secretion from endothelial cells through bradykinin. Hypertension 21:921-924, 1993
160. UEMASU J, MUNEMURA C, FUJIHARA M, KAWASAKI H: Inhibition of plasma endothelin-1 concentration by captopril in patients with essential hypertension. Clin Nephrol 41:150-152, 1994
161. RUIZ ORTEGA M, GONZALEZ E, EGIDO J: Molecular characterization of angiotensin II effects on renal interstitial fibroblasts (abstract). J Am Soc Nephrol 69:909, 1995
162. FUJIBAYASHI M, FUJIWARA Y, FUKUNAGA M, MORIYAMA T, SHOJI T, OCHI S, SHIN SH: Vasoconstrictors stimulate interleukin-6 (IL-6) release from mouse mesangial cells (MC) (abstract). J Am Soc Nephrol 2:437, 1991
163. NEUWIRTH R, SATRIANO JA, DECANDIDO S, CLAY K, SCHLONDORFF D: Angiotensin II causes formation of platelet activating factor in cultured rat mesangial cells. Circ Res 64:1224-1229, 1989
164. VERTES V, GRAUEL JA, GOLDBLATT H: Renal arteriography, separate renal-function studies and renal biopsy in human hypertension. N Engl J Med 270:656-659, 1964
165. DAVIS BA, CROOK JE, VESTAL RE, OATES JA: Prevalence of renovascular hypertension in patients with grade III or IV hypertensive retinopathy. N Engl J Med 301:1273-1276, 1979
166. WAGNER J, HAUFE CC, WYSTRYCHOWSKI A, FRICK S, GANTEN D, RITZ E: Accelerated progression of renal failure in transgenic rats carrying an additional renin gene [TGR (mREN2) 27] (abstract). J Am Soc Nephrol 3:448, 1992
167. BATTLE T, SCHNELL C, BUNKENBURG B, HEUDES D, WOOD JM, MENARD J: Continuous versus intermittent angiotensin converting enzyme inhibition in renal hypertensive rats. Hypertension 22:188-196, 1993
168. GARG UC, HASSID A: Inhibition of rat mesangial cell mitogenesis by nitric oxide-generating vasodilators. Am J Physiol 257:F60-F66, 1989
169. TRACHTMAN H, FUTTERWEIT S, SINGHAL P: Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells. Biochem Biophys Res Commun 207:120-125, 1995
170. KOLPAKOV V, GORDON D, KULIK TJ: Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circ Res 76:305-309, 1995
171. MENE P, MCDERMOTT RG, DUNN MJ: Modulation of mesangial cell proliferation by prostaglandins. Kidney Int 33:276, 1988
172. RENNKE HG, KLEIN PS: Pathogenesis and significance of nonprimary focal and segmental glomerulosclerosis. Am J Kidney Dis 13:443-456, 1989
173. REMUZZI G, BERTANI T: Is glomerulosclerosis a consequence of altered glomerular permeability to macromolecules? Kidney Int 38: 384-394, 1990
174. RENNKE HG, ANDERSON S, BRENNER BM: The progression of renal disease: Structural and functional correlations, in Renal Pathology with Clinical and Functional Correlations (2nd ed), edited by TISHER CC, BRENNER BM, Philadelphia, Lippincott, 1994, pp 116-139
175. BRUGGEMAN LA, HORIGAN EA, HORIKOHI S, RAY PE, KLOTMAN RE: Thromboxane stimulates synthesis of extracellular matrix proteins in vitro. Am J Physiol 261:F488-F494, 1991
176. ORTIZ A, BUSTOS C, ALONSO J, ALCAZAR R, LOPEZ-ARMADA MJ, PLAZA JJ, GONZALEZ E, EGIDO J: Involvement of tumor necrosis factor-α in the pathogenesis of experimental and human glomerulonephritis. Adv Nephrol 24:53-77, 1995
177. GANS R, HOORNTJE S: Bartter's syndrome, in Oxford Textbook of Clinical Nephrology, edited by CAMERON S, DAVISON A, GRÜNFELD J, KERR D, RITZ E, New York, Oxford University Press, 1992, pp 782-789
178. YOSHIDA H, KARUCHI J, YOSHIKAWA N, SARUTA T, INAGAMI T, PHILLIPS JA III, ICHIKAWA I: Angiotensin II type receptor gene abnormality in a patient with Bartter's syndrome. Kidney Int 46:1505-1509, 1994
179. DUNN MJ: Nephrology Forum: Prostaglandins and Bartter's syndrome. Kidney Int 19:86-102, 1981
180. D'AMICO G: Clinical factors in progressive renal injury. The role of proteinuria. Am J Kidney Dis 17(suppl 1):48-52, 1991
181. GABER L, WALTON C, BROWN S, BAKRIS G: Effects of different antihypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs. Kidney Int 46:161-169, 1994
182. KANSE SM, TAKAHASHI K, LAM HC, REES A, WARREN JB, PORTA M, MOLJNATI P, GHATEI M, BLOOM SR: Cytokines stimulated endothelin release from endothelial cells. Life Sci 48:1379-1384, 1991
183. GRETZ N, WALDHERR R, STRAUCH M: The remnant kidney model, in Experimental and Genetic Rat Models of Chronic Renal Failure, edited by GRETZ M, STRAUCH M, Basel, Karger, 1993, pp 1-28
184. PUPILLI C, CHEVALIER RL, CAREY RM, GOMEZ A: Distribution and content of renin and renin mRNA in remnant kidney of adult rat. Am J Physiol 263:F731-F738, 1992
185. CORREA-ROTTER R, HOSTETTER TH, MANIVEL JC, ROSENBERG ME: Renin expression in renal ablation. Hypertension 20:483-490, 1992
186. SHAH SV: Role of reactive oxygen metabolites in experimental glomerular disease. Kidney Int 35: 1093-1106, 1989
187. OHISHI A, SUZUKI H, NAKAMOTO H, KATSUMATA H, SAKAGUCHI H, SARUTA T: Differences in the effects of angiotensin converting enzyme inhibitors with or without a thiol group in chronic renal failure in rats. Clin Sci 76:353-356, 1989
188. ANDREOLI SP: Captopril scavenges hydrogen peroxide and reduces, but does not eliminate, oxidant-induced cell injury. Am J Physiol 264:F120-F127, 1993
189. MARWORTH A, BRODGEN R: Quinapril. A review of its pharmalogical properties and therapeutic efficacy in cardiovascular disorders. Drugs 41:378-399, 1991
190. WEBER KT, BRILLA CG: Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83:1849-1865, 1991
191. BRILLA CG, MAISUBARA LS, WEBER KT: Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism. J Mol Cell Cardiol 25:563-575, 1993
192. HATEKEYAMA H, MIYAMORI J, FUJITA T, TAKEDA Y, TAKEDA R, YAMAMOTO H: Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells. J Biol Chem 269: 24316-24320, 1994
193. TAKEDA R, HATEKEYAMA H, TAKEDA Y, IKI K, MIYAMORI I, SHENG WP, YAMAMOTO H, BLAIR IA: Aldosterone biosynthesis and action in vascular cells. Steroids 60:120-124, 1995
194. KELLY CJ, TOMASZEWSKI JE, NEILSON EG: Immunopathogenic mechanisms of tubulointerstitial injury, in Renal Pathology with Clinical and Functional Correlations (2nd ed). edited by TISHER CC, BRENNER BM, Philadelphia, Lippincott, 1994, pp 699-722
195. MARINIDES GN, GROGGEL GC, COHAN AH, COOK T, BARANOWSKI RL, WESTENFELDER C, BORDER WA: Failure of angiotensin converting enzyme inhibition to affect the course of chronic puromycin aminonucleoside nephropathy. Am J Pathol 129:394-401, 1987
196. TANAKA R, KON V, YOSHOKA T, ICHIKAWA I, FOGO A: Angiotensin converting enzyme inhibitor modulates glomerular function and structure by distinct mechanisms. Kidney Int 45:537-543, 1994
197. IKOMA M, KAWAMURA T, KARINUMA Y, FOGO A, ICHIKAWA I: Cause of variable therapeutic efficiency of angiotensin converting enzyme inhibitor on glomerular lesions. Kidney Int 40:195-202, 1991
198. RAKUGI H, KIM DK, KRIEGER JE, WANG DS, DZAU VJ, PRATT RE: Induction of angiotensin converting enzyme in the neointima after vascular injury. J Clin Invest 93:339-346, 1994
199. JOHNSTON CI, FABRIS B, YAMADA H, MENDELSON FAO, CUBELA R, SIVELL D, JACKSON J: Comparative studies of tissue inhibition by angiotensin converting enzyme inhibitors. J Hypertens 7(suppl 5): S11-S16, 1989
200. WOLF G, KILLEN P, NEILSON EG: Cyclosporine A stimulates procollagen transcription and synthesis in tubulointerstitial fibroblasts and proximal tubular cells. J Am Soc Nephrol 1:918-922, 1990
201. ALVAREZ RJ, SUN MJ, HAVERTY TP, IOZZO RV, MYERS JC, NEILSON EG: Biosynthetic and proliferate characteristics of tubulointerstital fibroblasts probed with paracrine cytokines. Kidney Int 41: 14-23, 1992
202. MULLER GA, RODEMANN HP: Characterization of human renal fibroblasts in health and disease: I. Immunophenotyping of cultured tubular epithelial cells and fibroblasts derived from kidneys with histologically proven interstitial fibrosis. Am J Kidney Dis 6:680-683, 1991
203. RODEMAN HP, MULLER GA: Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis. Am J Kidney Dis 6:684-686, 1991
204. WEBER MA, NEUTEL JM, SMITH DHG: Circulatory and extracirculatory effects of angiotensin-converting enzyme inhibition. Am Heart J 123:1414-1420, 1992
205. BACHMANN S, MUNDEL P: Nitric oxide in the kidney: synthesis, localization, and function. Am J Kidney Dis 24(1): 112-129, 1994
206. HERBERT LA, BAIN RP, VERME D, CATTRAN D, WHITTIER FC, TOLCHIN N, ROHDE RD, LEWIS EJ: Remission of nephrotic range proteinuria in type I diabetes. Kidney Int 46:1688-1693, 1994
207. SINNIAH R, LAW CH, PWEE HS: Glomerular lesions in patients with asymptomatic persistent and orthostatic proteinuria discovered on routine medical examination. Clin Nephrol 7:1-4, 1977
208. KLAHR S, LEVEY AS, BECK GJ, CAGGIULA AW, HUNSICKER L, KUSEK JW, STRIKER G: The effects of dietary protein restriction and blood pressure control on the progression of chronic renal disease. N Engl J Med 330:877-884, 1994
209. RUGGENENTI P, MOSCONI L, BIANCHI L, CORTESI L, CAMPANA M, PAGANI G, MECCA G, REMUZZI G: Long-term treatment with either enalapril or nitrendipine stabilizes albuminuria and increases glomerular filtration rate in non-insulin-dependent diabetic patients. Am J Kidney Dis 24:753-761, 1994
210. MILLER RB, HARRINGTON JT, RAMOS CP, RELMAN AS, SCHWARTZ WB: Long-term results of steroid therapy in adults with idiopathic nephrotic syndrome. Am J Med 46:919-929, 1969
211. DOI T, VLASSARA H, KIRSTEIN M, YAMADA Y, STRIKER GE, STRIKER LJ: Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor. Proc Natl Acad Sci USA 89(7):2873-2877, 1992
212. VLASSARA H: Receptor-mediated interactions of advanced glycosylation end products with cellular components within diabetic tissues. Diabetes 41(suppl 2):52-56, 1992
213. KAMPER AL, NIELSEN OJ: Effect of enalapril on hemoglobin and serum erythropoietin in patients with chronic nephropathy. Scand J Clin Lab Invest 50:611-618, 1990
214. PRATT MC, LEWIS-BARNED NJ, WALKER RJ, BAILEY RR, SHAND BI, LIVESEY J: Effect of angiotensin converting enzyme inhibitors on erythropoietin concentrations in healthy volunteers. Br J Clin Pharmacol 34:363-365, 1992
215. JENSEN JD, EISKJAER H, MADSEN B, EGEBLAD M, NIELSEN CB, PEDERSEN EB: Effect of captopril on the renal veno-arterial gradient of erythropoietin and oxygen in unilateral renal artery disease. Scand J Clin Lab Invest 53: 859-865, 1993
216. TORREGROSA JV, CAMPISTOL JM, MONTESINOS M, ROGADA AG, OPPENHEIMER F, ANDREU J: Efficacy of captopril on posttransplant erythrocytosis. Long-term follow-up. Transplantation 58:311-314, 1994
217. BRILLA CG, REAMS GP, MAISCH B, WEBER KT: Renin-angiotensin system and myocardial fibrosis in hypertension: regulation of the myocardial collagen matrix. Eur Heart J (suppl):J57-J61, 1993
218. WEBER KT, SUN Y, TYAGI SC, CLEUTJENS JP: Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol 26:279-292, 1994
219. GUARDA E, KATWA LC, MYERS PR, TYAGI SC, WEBER KT: Effects of endothelins on collagen turnover in cardiac fibroblasts. Cardiovasc Res 27:2130-2134, 1993
220. SIMONSON MS, JONES JM, DUNN MJ: Differential regulation of fos and jun gene expression and AP-1 cis-element activity by endothelin isopeptides. Possible implications for mitogenic signaling by endothelin. J Biol Chem 267:8643-8649, 1992
221. ROBERTS AB, MCCUNE BK, SPORN MB: TGFβ: Regulation of extracellular matrix. Kidney Int 41:557-559, 1992
222. ARAI M, WADA A, ISAKA Y, AKAGI Y, SUGIURA T, MIYAZAKI M, MORIYAMA T, KANEDA Y, NARUSE K, NARUSE M, ORITA Y, ANDO A, KAMADA T, UEDA N, IMAI E: In vivo transfection of genes for renin and angiotensinogen into the glomerular cells induced phenotypic change of the mesangial cells and glomerular sclerosis. Biochem Biophys Res Commun 206:525-532, 1995
223. KUANE WF, RAIJ L: Relationship among altered glomerular barrier permselectivity, angiotensin II, and mesangial uptake of macromolecules. Lab Invest 52:599-604, 1985
224. MICHEL B, GRIMA M, COQUARD C, WELSH C, BARTHELMEBS M, IMBS JL: Effect of dietary protein and uninephrectomy on renal angiotensin converting enzyme activity in the rat. Kidney Int 45:1587-1592, 1994
225. KIM S, OHTA K, HAMAGUCHI, OMURA T, YUKIMURA Y, INADA Y, WADA T, ISHIMURA Y, CHATANI F, IWAO H: Contribution of renal angiotensin II type I receptor to gene expressions in hypertension-induced renal injury. Kidney Int 46:1346-1358, 1994
226. FUJIWARA Y, TAKAMA T, SHIN S, OCHI S, FUKUNAGA M, ORITA Y, KAMADA T: Angiotcnsin II (AII) stimulates mesangial cell growth through phosphoinositide (PI) cascade (abstract). Proc Am Soc Nephrol 24A, 1988
227. HOMMA T, HOOVER RL, ICHIKAWA I, HARRIS RC: Angiotensin II (AII) induces hypertrophy and stimulates collagen production in cultured rat mesangial cell (MC) (abstract). Clin Res 38: 358, 1990
228. WOLTHUIS A, BOES A, RODEMANN HP, GROND J: Vasoactive agents affect growth and protein synthesis of cultured rat mesangial cells. Kidney Int 41:124-131, 1992
229. ORTH S, WEINREICH T, BONISCH S, WEIH M, RITZ E: Angiotensin II induces hypertrophy and hyperplasia in adult human mesangial cells. Exp Nephrol 3:23-33, 1995