Heat-provoked skin vasodilatation in innervated and denervated trunk dermatomes in human spinal cord injury

Spinal Cord

Volumn 44, Issue 4, 2006, Pages 222-226

  Nicotra, A ^a,b,c   Asahina, M ^a,b,d   Young, T M ^a,b   Mathias, C J ^a,b,c  

^a ST MARY S HOSPITAL   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c STOKE MANDEVILLE HOSPITAL   (United Kingdom)

^d CHIBA UNIVERSITY   (Japan)

Author keywords

Axon reflex; Skin blood flow; Spinal cord injury; Sympathetic system; Vasodilatation

Indexed keywords

ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DENERVATION; DERMATOME; FEMALE; HEAT; HEATING; HOSPITAL; HUMAN; INNERVATION; LASER; LASER DOPPLER FLOWMETRY; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; SCORING SYSTEM; SKIN; SKIN BLOOD FLOW; SPINAL CORD INJURY; STATISTICAL SIGNIFICANCE; THERMOSTABILITY; TRUNK; UNITED KINGDOM; VASODILATATION; VASOMOTOR REFLEX;

ADULT; AUTONOMIC NERVOUS SYSTEM DISEASES; BLOOD VESSELS; BODY TEMPERATURE REGULATION; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DENERVATION; FEMALE; HEAT; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; MIDDLE AGED; PERIPHERAL NERVES; REFLEX, ABNORMAL; REGIONAL BLOOD FLOW; SKIN; SPINAL CORD INJURIES; SYMPATHETIC FIBERS, POSTGANGLIONIC; VASODILATION; VASOMOTOR SYSTEM;

EID: 33645743168     PISSN: 13624393     EISSN: 14765624     Source Type: Journal    
DOI: 10.1038/sj.sc.3101837     Document Type: Article

References (19)

1. Harati Y. Autonomie disorders associated with spinal cord injury. In: Low PA (ed). Clinical Autonomic Disorders. 2nd edn. Lippincott-Raven Publishers: New York, USA 1997, pp 455-461.
2. Mathias CJ, Frankel HL. Autonomic disturbances in spinal cord lesions. In: Mathias CJ, Bannister R (eds). Autonomic Failure. A Textbook of Clinical Disorders of the Autonomic Nervous System. 4th edn. Oxford University Press: New York, USA 2002. pp 494-513.
3. Minson CT, Berry LT, Joyner MJ. Nitric oxide and neurally mediated regulation of skin blood flow during local heating. J Appl Physiol 2001; 91: 1619-1626.
4. Hornyak ME, Naver HK, Rydenhag B, Wallin G. Sympathetic activity influences the vascular axon reflex in the skin. Acta Physiol Scand 1990; 139: 77-84.
5. Cariga P, Catley M, Mathias CJ, Savic G, Frankel HL, Ellaway PH. Organisation of the sympathetic skin response in spinal cord injury. J Neurol Neurosurg Psychiatry 2002; 72: 356-360.
6. Kuesgen B, Frankel HL, Anand P. Decreased cutaneous sensory axon-reflex vasodilatation below the lesion in patients with complete spinal cord injury. Somatosens Mot Res 2002; 19: 149-152.
7. Nicotra A, Asahina M, Mathias CJ. Skin vasodilator response to local heating in human chronic spinal cord injury. Eur J Neurol 2004; 11: 835-837.
8. Maynard Jr FM et al. International standards for neurological and functional classification of spinal cord injury. American Spinal Injury Association. Spinal Cord 1997; 35: 266-274.
9. Häbler HJ, Wasner G, Jänig W. Interaction of sympathetic vasoconstriction and antidromic vasodilatation in the control of skin blood flow. Exp Brain Res 1997; 113: 402-410.
10. Mathias CJ, Christensen NJ, Corbett JL, Frankel HL, Spalding JM. Plasma catecholamines during paroxysmal neurogenic hypertension in quadriplegic man. Circ Res 1976; 39: 204-208.
11. Mathias CJ, Frankel HL, Turner RC, Christensen NL. Physiological responses to insulin hypoglycaemia in spinal man. Paraplegia 1979; 17: 319-326.
12. Mathias CJ. Neurological disturbances of the cardiovascular system. Doctor of Philosophy Thesis, University of Oxford, 1976.
13. Magnifico F, Misra VP, Murray NMF, Mathias CJ. The sympathetic skin response in peripheral autonomie failure - evaluation in pure autonomie failure, pure cholinergic dysautonomia and dopamine-beta-hydroxylase deficiency. Clin Auton Res 1998; 8: 133-138.
14. Curt A, Weinhardt C, Diets V. Significance of sympathetic skin response in the assessment of autonomie failure in patients with spinal cord injury. J Auton Nerv Syst 1996; 61: 175-180.
15. Curt A, Nitsche B, Rodic B, Scurch B, Dietz V. Assessment of autonomie dysreflexia in patients with spinal cord injury. J Neurol Neurosurg Psychiatry 1997; 62: 473-477.
16. Lewis T, Pickering GW. Vasodilatation in the limbs in response to warming the body; with evidence for sympathetic vasodilator nerves in man. Heart 1931; 16: 33-51.
17. Roddie IC, Shepherd JT, Whelan RF. The contribution of constrictor and dilator nerves to the skin vasodilatation during body heating. J Physiol 1957; 136: 489-497.
18. Roddie IC. Sympathetic vasodilatation in human skin. J Physiol 2003; 548: 336-337.
19. Roddie IC. In: Shepherd JT, Abboud FM (eds). Handbook of Physiology. Section 2. The Cardiovascular System, Vol III, Part 1. Am Physiol Society: Bethesda 1983. pp 285-317.