Nicotinamide increases thyroid radiosensitivity by stimulating nitric oxide synthase expression and the generation of organic peroxides

Hormone and Metabolic Research

Volumn 38, Issue 1, 2006, Pages 12-15

  Agote Robertson, M ^a   Finochietto, P ^b   Gamba, C A ^a   Dagrosa, M A ^a   Viaggi, M E ^a   Franco, M C ^b   Poderoso, J J ^b   Juvenal, C J ^a   Pisarev, Mario A ^a,c  

^a DEPARTAMENTO DE FÍSICA   (Argentina)

^b HOSPITAL DE CLÍNICAS JOSÉ DE SAN MARTÍN   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Nicotinamide; Nitric oxide; Radiation; Radiosensitivity; Thyroid

Indexed keywords

CATALASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE PEROXIDASE; IODINE 131; NICOTINAMIDE; NITRIC OXIDE SYNTHASE; PEROXIDE; RADIOACTIVE IODINE; RADIOSENSITIZING AGENT; SUPEROXIDE DISMUTASE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; GOITER; HYPERTHYROIDISM; MALE; NONHUMAN; ORGAN BLOOD FLOW; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOISOTOPE THERAPY; RADIOSENSITIVITY; RAT; THYROID BLOOD FLOW; THYROID CANCER; THYROID GLAND; TISSUE INJURY; TISSUE OXYGENATION; WESTERN BLOTTING;

ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERTHYROIDISM; IODINE RADIOISOTOPES; MALE; NIACINAMIDE; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; PEROXIDES; RATS; RATS, WISTAR; THYROID GLAND; THYROID NEOPLASMS; VITAMIN B COMPLEX;

ANIMALIA; RATTUS NORVEGICUS;

EID: 33645724194     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-924966     Document Type: Article

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