A prospective, double-blind phase II study evaluating the safety and efficacy of a topical histamine gel for the prophylaxis of oral mucositis in patients post hematopoietic stem cell transplantation

Bone Marrow Transplantation

Volumn 37, Issue 8, 2006, Pages 757-762

  Elad, S ^a   Ackerstein, A ^b   Bitan, M ^b   Shapira, M Y ^b   Resnick, I ^b   Gesundheit, B ^b   Cohen, Y ^a   Diss, O ^a   Barak, D ^b   Dray, L ^b   Or, R ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Histamine dihydrochloride; HSCT; Mucositis; Oral

Indexed keywords

AMPHOTERICIN B; BUSULFAN; CHLORHEXIDINE; HISTAMINE; PLACEBO; TARODENT;

ABSENCE OF SIDE EFFECTS; ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOPROPHYLAXIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; GEL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LONGITUDINAL STUDY; MALE; MOUTH PAIN; MUCOSA INFLAMMATION; ORAL MUCOSAL DISEASE; PATIENT COMPLIANCE; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SALIVATION; SCORING SYSTEM; STATISTICAL ANALYSIS; VISUAL ANALOG SCALE; WHOLE BODY RADIATION;

AGED; ANTI-INFLAMMATORY AGENTS; DOUBLE-BLIND METHOD; FEMALE; GELS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTAMINE; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; MUCOSITIS; PLACEBOS; PROSPECTIVE STUDIES; RANDOM ALLOCATION; REPRODUCIBILITY OF RESULTS; STOMATITIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 33645718196     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705331     Document Type: Article

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