A glutamine to glutamate mutation at position 170 (Q170E) in the rabbit Na+/glucose cotransporter, rSGLT1, enhances binding affinity for Na+

Biochemistry

Volumn 45, Issue 14, 2006, Pages 4653-4663

  Huntley, Steven A ^a   Krofchick, Daniel ^a   Silverman, Mel ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOELECTRIC POTENTIALS; BIOLOGICAL MEMBRANES; ELECTRIC POTENTIAL; GLUCOSE;

ANIONIC SODIUM; CYSTEINE MUTAGENESIS; PUTATIVE LOOP; TRANSMEMBRANE SEGMENTS;

GENETIC ENGINEERING;

(2 AMINOETHYL)METHANETHIOSULFONATE HYDROBROMIDE; (2 SULFONATOETHYL)METHANETHIOSULFONATE; ANION; CARBOHYDRATE BINDING PROTEIN; CATION; CYSTEINE; GLUCOPYRANOSIDE; GLUTAMIC ACID; GLUTAMINE; MESYLIC ACID DERIVATIVE; PROTEIN RSGLT1; SODIUM; SODIUM GLUCOSE COTRANSPORTER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; COMPUTER SIMULATION; GENE MUTATION; MICROELECTRODE; MUTAGENESIS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RABBIT; VOLTAGE CLAMP; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; COMPUTER SIMULATION; GLUTAMIC ACID; GLUTAMINE; MEMBRANE POTENTIALS; METHYLGLUCOSIDES; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; RABBITS; SODIUM; SODIUM-GLUCOSE TRANSPORTER 1; XENOPUS LAEVIS;

ORYCTOLAGUS CUNICULUS;

EID: 33645670616     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052267m     Document Type: Article

References (14)

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