Transition states of the high-affinity rabbit Na+/glucose cotransporter SGLT1 as determined from measurement and analysis of voltage-dependent charge movements

American Journal of Physiology - Cell Physiology

Volumn 287, Issue 1 56-1, 2004, Pages

  Krofchick, Daniel ^a   Huntley, Steven A ^a   Silverman, Mel ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Boltzmann distribution; SGLT1; Sodium glucose cotransport; Two electrode voltage clamp; Xenopus oocyte

Indexed keywords

COTRANSPORTER; GLUCOSE; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM ION; SUGAR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; GLUCOSE TRANSPORT; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MICROELECTRODE; MODEL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SODIUM TRANSPORT; STATISTICAL DISTRIBUTION; STEADY STATE; VOLTAGE CLAMP; XENOPUS;

ANIMALS; BINDING, COMPETITIVE; FEMALE; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; MONOSACCHARIDE TRANSPORT PROTEINS; PATCH-CLAMP TECHNIQUES; RABBITS; REACTION TIME; SODIUM-GLUCOSE TRANSPORTER 1; XENOPUS LAEVIS;

ANIMALIA; CHEN; ORYCTOLAGUS CUNICULUS;

EID: 2942638423     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00008.2004     Document Type: Article

References (20)

1. Armstrong CM and Bezanilla F. Currents associated with the ionic gating structures in nerve membrane. Ann NY Acad Sci 264: 265-277, 1975.
2. Chen XZ, Coady MJ, Jackson F, Berteloot A, and Lapointe JY. Thermodynamic determination of the Na:glucose coupling ratio for the human SGLT1 cotransporter. Biophys J 69: 2405-2414, 1995.
3. +-glucose cotransporter. Biophys J 71: 2544-2552, 1996.
4. +/glucose cotransporter (SGLT1). J Membr Biol 155: 175-186, 1997.
5. +/glucose cotransporter. Nature 330: 397-381, 1987.
6. +/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes. J Biol Chem 271: 14740-14746, 1996.
7. +/glucose cotransporter. Biophys J 84: 3690-3702, 2003.
8. +/glucose cotransporter SGLT1. J Biol Chem 273: 29341-29351, 1998.
9. Lo B and Silverman M. Replacement of Ala-166 with cysteine in the high affinity rabbit sodium/glucose transporter alters transport kinetics and allows methanethiosulfonate ethylamine to inhibit transporter function. J Biol Chem 273: 903-909, 1998.
10. +/glucose cotransporter. Proc Natl Acad Sci USA 90: 5767-5771, 1993.
11. + and glucose transport. Proc Natl Acad Sci USA 95: 7789-7794, 1998.
12. +/glucose cotransporter (SGLT1) currents and fluxes. J Membr Biol 162: 101-106, 1998.
13. +/glucose cotransporter. Biochemistry 41: 1250-1258, 2002.
14. Oulianova N, Falk S, and Berteloot A. Two-step mechanism of phlorizin binding to the SGLT1 protein in the kidney. J Membr Biol 179: 223-242, 2001.
15. +/glucose cotransporter SGLT1. Biochemistry 37: 10522-10528, 1998.
16. Panayotova-Heiermann M, Loo DDF, Lostao MP, and Wright EM. Sodium/D-glucose cotransporter charge movements involve polar residues. J Biol Chem 269: 21016-21020, 1994.
17. +/glucose cotransporter. J Biol Chem 270: 27099-27105, 1995.
18. +/glucose cotransporter. I. Voltage-clamp studies. J Membr Biol 125: 49-62, 1992.
19. Wright EM, Loo DDF, Panayotova-Heiermann M, Lostao MP, Hirayama BH, Mackenzie B, Boorer K, and Zampighi G. 'Active' sugar transport in eukaryotes. J Exp Biol 196: 197-212, 1994.
20. Zampighi GA, Kreman M, Boorer K, Loo DDF, Bezanilla F, Chandy G, Hall JE, and Wright EM. A method for determining the unitary function capacity of cloned channels and transporters expressed in Xenopus laevis oocytes. J Membr Biol 148: 65-78, 1995.