Ubiquitin immunohistochemistry of frontotemporal lobar degeneration differentiates cases with and without motor neuron disease

Alzheimer Disease and Associated Disorders

Volumn 19, Issue SUPPL. 1, 2005, Pages

  Katsuse, Omi ^a   Dickson, Dennis W ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Frontotemporal lobar degeneration; Motor neuron disease; Neuronal intranuclear inclusions; Ubiquitin

Indexed keywords

UBIQUITIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN DEGENERATION; CAUDATE NUCLEUS; CELL NUCLEUS INCLUSION BODY; CONFERENCE PAPER; DEMENTIA; FEMALE; FRONTAL CORTEX; FRONTAL LOBE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MOTOR NEURON DISEASE; NEURITE; NEUROPATHOLOGY; PRIORITY JOURNAL; TAUOPATHY; TEMPORAL CORTEX; TEMPORAL LOBE; ARTICLE; BRAIN CORTEX; CASE CONTROL STUDY; DENTATE GYRUS; METABOLISM; MIDDLE AGED; PATHOLOGY; PICK PRESENILE DEMENTIA;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; CEREBRAL CORTEX; DENTATE GYRUS; FEMALE; HUMANS; INTRANUCLEAR INCLUSION BODIES; MALE; MIDDLE AGED; MOTOR NEURON DISEASE; PICK DISEASE OF THE BRAIN; UBIQUITIN;

EID: 33645642025     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wad.0000183889.61421.a8     Document Type: Conference Paper

References (31)

1. The Lund and Manchester Groups. Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry. 1994;57:416-418.
2. Brun A. Frontal lobe degeneration of non-Alzheimer type. I. Neuropathology. Arch Gerontol Geriatr. 1987;6:193-208.
3. Neary D, Snowden JS, Northen B, et al. Dementia of frontal lobe type. J Neurol Neurosurg Psychiatry. 1988;51:353-361.
4. Neary D, Snowden JS, Gustafson L, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology. 1998;51:1546-1554.
5. Knopman DS, Mastri AR, Frey WH2nd, et al. Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia. Neurology. 1990;40:251-256.
6. Kertesz A, Munoz D. Pick's disease, frontotemporal dementia, and Pick complex: emerging concepts. Arch Neurol. 1998;55:302-304.
7. Snowden JS, Neary D, Mann DM. Frontotemporal Lobar Degeneration: Frontotemporal Dementia, Progressive Aphasia, Semantic Dementia. London, England: Churchill-Livingstone; 1996.
8. McKhann GM, Albert MS, Grossman M, et al. Work Group on Frontotemporal Dementia and Pick's Disease. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch Neurol. 2001;58:1803-1809.
9. Bergmann M, Kuchelmeister K, Schmid KW, et al. Different variants of frontotemporal dementia: a neuropathological and immunohistochemical study. Acta Neuropathol. 1996;92:170-179.
10. Tolnay M, Probst A. Frontal lobe degeneration: novel ubiquitin- immunoreactive neurites within frontotemporal cortex. Neuropathol Appl Neurobiol. 1995;21:492-497.
11. Hudson AJ. Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review. Brain. 1981;104:217-247.
12. Mitsuyama Y. Presenile dementia with motor neuron disease in Japan: clinico-pathological review of 26 cases. J Neurol Neurosurg Psychiatry. 1984;47:953-959.
13. Okamoto K, Hirai S, Yamazaki T, et al. New ubiquitin-ir intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis. Neurosci Lett. 1991;129:233-236.
14. Okamoto K, Murakami N, Kusaka H, et al. Ubiquitin-ir intraneuronal inclusions in the extramotor cortices of presenile dementia patients with motor neuron disease. J Neurol. 1992;239:426-430.
15. Wakabayashi K, Piao YS, Hayashi S, et al. Ubiquitinated neuronal inclusions in the neostriatum in patients with amyotrophic lateral sclerosis with and without dementia-a study of 60 patients 31 to 87 years of age. Clin Neuropathol. 2001;20:47-52.
16. Piao YS, Wakabayashi K, Kakita A, et al. Neuropathology with clinical correlations of sporadic amyotrophic lateral sclerosis: 102 autopsy cases examined between 1962 and 2000. Brain Pathol. 2003;13:10-22.
17. Gwinn-Hardy K, Mehta ND, Farrer M, et al. Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol. 2000;99:663-672.
18. Josephs KA, Holton JL, Rossor MN, et al. Neurofilament inclusion body disease: a new proteinopathy? Brain. 2003;126:2291-2303.
19. Zhukareva V, Vogelsberg-Ragaglia V, Van Deerlin VM, et al. Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Ann Neurol. 2001;49:165-175.
20. Broe M, Hodges JR, Schofield E, et al. Staging disease severity in pathologically confirmed cases of frontotemporal dementia. Neurology. 2003;60:1005-1011.
21. Tolnay M, Probst A. Frontotemporal lobar degeneration-tau as a pied piper? Neurogenetics. 2002;4:63-75.
22. Cooper PN, Jackson M, Lennox G, et al. Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia. Arch Neurol. 1995;52:1011-1015.
23. Jackson M, Lennox G, Lowe J. Motor neurone disease-inclusion dementia. Neurodegeneration. 1996;5:339-350.
24. Ikeda K, Akiyama H, Arai T, et al. Morphometrical reappraisal of motor neuron system of Pick's disease and amyotrophic lateral sclerosis with dementia. Acta Neuropathol. 2002;104:21-28.
25. Iseki E, Li F, Odawara T, et al. Ubiquitin-immunohistochemical investigation of atypical Pick's disease without Pick bodies. J Neurol Sci. 1998;159:194-201.
26. Rosso SM, Kamphorst W, de Graaf B, et al. Familial frontotemporal dementia with ubiquitin-ir inclusions is linked to chromosome 17q21-22. Brain. 2001;124:1948-1957.
27. Woulfe J, Kertesz A, Munoz DG. Frontotemporal dementia with ubiquitinated cytoplasmic and intranuclear inclusions. Acta Neuropathol. 2001;102:94-102.
28. Mackenzie IR, Feldman H. Neuronal intranuclear inclusions distinguish familial FTD-MND type from sporadic cases. Acta Neuropathol. 2003;105:543-548.
29. Mackenzie IR, Feldman H. The relationship between extramotor ubiquitin-immunoreactive neuronal inclusions and dementia in motor neuron disease. Acta Neuropathol. 2003;105:98-102.
30. Wakabayashi K, Piao YS, Hayashi S, et al. Ubiquitinated neuronal inclusions in the neostriatum in patients with amyotrophic lateral sclerosis with and without dementia-a study of 60 patients 31 to 87 years of age. Clin Neuropathol. 2001;20:47-52.
31. Bancher C, Brunner C, Lassmann H, et al. Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res. 1989;477:90-99.