Mechanisms and physiological sequelae of reactive species injury to the alveolar epithelium

Chronic Lung Disease in Early Infancy

Volumn , Issue , 1999, Pages 431-456

  Haddad, Imad Y ^a   Zhu, Sha ^a   Tilden, Samuel J ^a   Matalon, Sadis ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33645604994     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (82)

1. Abman SH, Griebel JL, Parker DK, Schmidt JM, Swanton D, Kinsella JP. Acute effects of inhaled nitric oxide in children with severe hypoxemic respiratory failure. J Pediatr 1994; 124:881-888.
2. Asano K, Chee CB, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci USA 1994; 91:10089-10093.
3. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87:1620-1624.
4. Beckman JS, Ischiropoulos H, Zhu L, van der Woerd M, Smith C, Chen J, Harrison J, Martin JC, Tsai M. Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch Biochem Biophys 1992; 298:438-445.
5. Benzing A, Brautigam P, Geiger K, Loop T, Beyer U, Moser E. Inhaled nitric oxide reduces pulmonary transvascular albumin flux in patients with acute lung injury. Anesthesiology 1995; 83:1153-1161.
6. Blackford JA Jr, Antonini JM, Castranova V, Dey RD. Intratracheal instillation of silica up-regulates inducible nitric oxide synthase gene expression and increase nitric oxide production in alveolar macrophages and neutrophils. Am J Respir Cell Mol Biol 1994; 11:426-431.
7. Cantin AM, North SL, Hubbard RC, Crystal RG. Normal alveolar epithelial lining fluid contains high levels of glutathione. J Appl Physiol 1987; 63:152-157.
8. Carreras MC, Pargament GA, Catz SD, Poderoso JJ, Boveris A. Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils. FEBS Lett 1994; 341:65-68.
9. Cassin S, Perks AM. Amiloride inhibits arginine vasopressin-induced decrease in fetal lung liquid secretion. J Appl Physiol 1993; 75:1925-1929.
10. Cockshutt AM, Weitz J, Possmayer F. Pulmonary surfactant-associated protein A enhances the surface activity of lipid extract surfactant and reverses inhibition by blood proteins in vitro. Biochemistry 1990; 29:8424-8429.
11. Croen KD. Evidence for an antiviral effect of nitric oxide: inhibition of herpes simplex virus type 1 replication. J Clin Invest 1993; 91:2446-2452.
12. De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr, Shin WS, Liao JK. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995; 96:60-68.
13. Dimmeler S, Lottspeich F, Brune B. Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 1992; 267: 16771-16774.
14. Eigler A, Moeller J, Endres S. Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7. J Immunol 1995; 154:4048-4054.
15. Evans TJ, Buttery LDK, Carpenter A, Springall DR, Polak JM, Cohen J. Cytokine- treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci USA 1996; 93:9553-9558.
16. Fridovich I. Biological effects of the superoxide radical. Arch Biochem Biophys 1986; 247:1-11.
17. Frostell CG, Blomqvist H, Hedenstierna G, Lundberg J, Zapol WM. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology 1993; 78:427-435.
18. Gilliard N, Heldt GP, Loredo J, Gasser H, Redl H, Merritt TA, Spragg RG. Exposure of the hydrophobic components of porcine lung surfactant to oxidant stress alters surface tension properties. J Clin Invest 1994; 93:2608-2615.
19. Haagsman HP, Hawgood S, Sargeant T, Buckley D, White RT, Drickamer K, Benson BJ. The major lung surfactant protein, SP 28-36, is a calcium-dependent, carbohydrate-binding protein. J Biol Chem 1987; 262:13877-13880.
20. Haddad IY, Crow JP, Hu P, Ye Y, Beckman J, Matalon S. Concurrent generation of nitric oxide and superoxide damages surfactant protein A. Am J Physiol 1994; 267:L242-L249.
21. Haddad IY, Ischiropoulos H, Holm BA, Beckman JS, Baker JR, Matalon S. Mechanisms of peroxynitrite-induced injury to pulmonary surfactants. Am J Physiol 1993; 265:L555-L564.
22. Haddad IY, Pataki G, Hu P, Galliani C, Beckman JS, Matalon S. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest 1994; 94:2407-2413.
23. Haddad IY, Zhu S, Crow J, Barefield E, Gadilhe T, Matalon S. Inhibition of alveolar type II cell ATP and surfactant synthesis by nitric oxide. Am J Physiol 1996; 270: L898-906.
24. Haddad IY, Zhu S, Ischiropoulos H, Matalon S. Nitration of surfactant protein A results in decreased ability to aggregate lipids. Am J Physiol 1996; 270:L281- L288.
25. Halliwell B, Hu ML, Louie S, Duvall TR, Tarkington BK, Motchnik P, Cross CE. Interaction of nitrogen dioxide with human plasma. Antioxidant depletion and oxidative damage. FEBS Lett 1992; 313:62-66.
26. Hallman M, Bry K, Lappalainen U. A mechanism of nitric oxide-induced surfactant dysfunction. J Appl Physiol 1996; 80:2035-2043.
27. Hawgood S, Clements JA. Pulmonary surfactant and its apoproteins. J Clin Invest 1990; 86:1-6.
28. Heiss LN, Lancaster JR Jr, Corbett JA, Goldman WE. Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis. Proc Natl Acad Sci USA 1994; 91:267-270.
29. Holm BA, Enhorning G, Notter RH. A biophysical mechanism by which plasma proteins inhibit lung surfactant activity. Chem Phys Lipids 1988; 49:49-55.
30. Holm BA, Hudak BB, Keicher L, Cavanaugh C, Baker RR, Hu P, Matalon S. Mechanisms of H2O2-mediated injury to type II cell surfactant metabolism and protection with PEG-catalase. Am J Physiol 1991; 261:C751-C757.
31. Holm BA, Notter RH, Siegle J, Matalon S. Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia. J Appl Physiol 1985; 59:14021409.
32. Ischiropoulos H, Mendiguren I, Fisher D, Fisher AB, Thom SR. Role of neutrophils and nitric oxide in lung alveolar injury from smoke inhalation. Am J Respir Crit Care Med 1994; 150:337-341.
33. Ischiropoulos H, Zhu L, Beckman JS. Peroxynitrite formation from macrophage- derived nitric oxide. Arch Biochem Biophys 1992; 298: 446-451.
34. Kanner J, Harel S, Granit R. Nitric oxide as an antioxidant. Arch Biochem Biophys 1991; 289:130-136.
35. Kavanagh BP, Mouchawar A, Goldsmith J, Pearl RG. Effects of inhaled NO and inhibition of endogenous NO synthesis in oxidant-induced acute lung injury. J Appl Physiol 1994; 76:1324-1329.
36. Kharitonov SA, Yates D, Barnes PJ. Increased nitric oxide in exhaled air of normal human subjects with upper respiratory tract infections. Eur Respir J 1995; 8:295-297.
37. Kobzik L, Bredt DS, Lowenstein CJ, Drazen J, Gaston B, Sugarbaker D, Stamler JS. Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. Am J Respir Cell Mol Biol 1993; 9:371-377.
38. Kooy NW, Royall JA. Agonist-induced peroxynitrite production from endothelial cells. Arch Biochem Biophys 1994; 310:352-359.
39. Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88:4651-4655.
40. MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995; 81: 641-650.
41. Matalon S. Mechanisms and regulation of ion transport in adult mammalian alveolar type II pneumocytes. Am J Physiol 1991; 261:C727-C738.
42. Matalon S, DeMarco V, Haddad IY, Myles C, Skimming JW, Schurch S, Cheng S, Cassin S. Inhaled nitric oxide injures the pulmonary surfactant system of lambs in vivo. Am J Physiol Lung Cell Mol Physiol 1996; 270:L273-L280.
43. Matalon S, Egan EA. Interstitial fluid volumes and albumin spaces in pulmonary oxygen toxicity. J Appl Physiol 1984; 57:1767-1772.
44. McCormack FX, Calvert HM, Watson PA, Smith DL, Mason RJ, Voelker DR. The structure and function of surfactant protein A. Hydroxyproline- and carbohydrate- deficient mutant proteins. J Biol Chem 1994; 269:5833-5841.
45. Miles PR, Bowman L, Huffman L. Nitric oxide alters metabolism in isolated alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 1996; 271:L23-L30.
46. Muller B, Barth P, von Wichert P. Structural and functional impairment of surfactant protein a after exposure to nitrogen dioxide in rats protein A after exposure to nitrogen dioxide in rats. Am J Physiol 1992; 263:L177-L184.
47. Muller B, von Wichert P. Effect of nitrogen dioxide inhalation on surfactant phosphatidylcholine synthesis in rat alveolar type II cells. Biochim Biophys Acta 1993; 1170:38-43.
48. Mulligan MS, Hevel JM, Marletta MA, Ward PA. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc Natl Acad Sci USA 1991; 88: 6338-6342.
49. Nici L, Dowin R, Gilmore-Hebert M, Jamieson JD, Ingbar DH. Upregulation of rat lung Na-K-ATPase during hyperoxic injury. Am J Physiol 1991; 261:L307-L314.
50. Novotny WE, Hudak BB, Matalon S, Holm BA. Hyperoxic lung injury reduces exogenous surfactant clearance in vivo. Am J Respir Crit Care Med 1995; 151:1843-1847.
51. Ogasawara Y, McCormack FX, Mason RJ, Voelker DR. Chimeras of surfactant proteins A and D identify the carbohydrate recognition domains as essential for phospholipid interaction. J Biol Chem 1994; 269:29785-29792.
52. Olver RE, Robinson EJ. Sodium and chloride transport by the tracheal epithelium of fetal, new-born and adult sheep. J Physiol (Lond) 1986; 375:377-390.
53. Oosting RS, van Greevenbroek MM, Verhoef J, van Golde LM, Haagsman HP. Structural and functional changes of surfactant protein A induced by ozone. Am J Physiol 1991; 261:L77-L83.
54. Oosting RS, Van Iwaarden JF, Van Bree L, Verhoef J, van Golde LM, Haagsman HP. Exposure of surfactant protein A to ozone in vitro and in vivo impairs its interactions with alveolar cells. Am J Physiol 1992; 262:L63-L68.
55. Pacht ER, Davis WB. Role of transferrin and ceruloplasmin in antioxidant activity of lung epithelial lining fluid. J Appl Physiol 1988; 64:2092-2099.
56. Padgett EL, Pruett SB. Rat, mouse and human neutrophils stimulated by a variety of activating agents produce much less nitrite than rodent macrophages. Immunology 1995; 84:135-141.
57. Padmaja S, Huie RE. The reaction of nitric oxide with organic peroxyl radicals. Biochem Biophys Res Commun 1993;195:539-544.
58. Pendino KJ, Laskin JD, Shuler RL, Punjabi CJ, Laskin DL. Enhanced production of nitric oxide by rat alveolar macrophages after inhalation of a pulmonary irritant is associated with increased expression of nitric oxide synthase. J Immunol 1993; 151:7196-7205.
59. Persson AH, Schornagel JK, Tilders HFF, Vente DJ, Berkenbosch F, Kraal G. Alveolar macrophages autoregulate IL-1 and IL-6 production by endogenous nitric oxide. Am J Respir Cell Mol Biol 1996; 14:272-278.
60. Pikaar JC, Voorhout WF, van Golde LM, Verhoef J, Van Strijp JA, Van Iwaarden JF. Opsonic activities of surfactant proteins A and D in phagocytosis of gram-negative bacteria by alveolar macrophages. J Infect Dis 1995; 172:481-489.
61. Poss WB, Timmons OD, Farrukh IS, Hoidal JR, Michael JR. Inhaled nitric oxide prevents the increase in pulmonary vascular permeability caused by hydrogen peroxide. J Appl Physiol 1995; 79:886-891.
62. Pryor WA, Stone K. Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann NY Acad Sci 1993; 686:12-27; see discussion 27-8.
63. Punjabi CJ, Laskin JD, Pendino KJ, Goller NL, Durham SK, Laskin DL. Production of nitric oxide by rat type II pneumocytes: increased expression of inducible nitric oxide synthase following inhalation of a pulmonary irritant. Am J Respir Cell Mol Biol 1994; 11:165-172.
64. Radi R, Rodriguez M, Castro L, Telleri R. Inhibition of mitochondrial electron transport by peroxynitrite. Arch Biochem Biophys 1994; 308:89-95.
65. Revak SD, Merritt TA, Hallman M, Cochrane CG. Reconstitution of surfactant activity using purified human apoprotein and phospholipids measured in vitro and in vivo. Am Rev Respir Dis 1986; 134:1258-1265.
66. Robbins CG, Davis JM, Merritt TA, Amirkhanian JD, Sahgal N, Morin FC 3rd, Horowitz S. Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation. Am J Physiol 1995; 269:L545-L550.
67. Rossaint R, Falke KJ, Lopez F, Slama K, Pison U, Zapol WM. Inhaled nitric oxide for the adult respiratory distress syndrome [see comments]. N Engl J Med 1993; 328:399-405.
68. Rubbo H, Radi R, Trujillo M, Telleri R, Kalyanaraman B, Barnes S, Kirk M, Freeman BA. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J Biol Chem 1994; 269:26066-26075.
69. Ryan SF, Ghassibi Y, Liau DF. Effects of activated polymorphonuclear leukocytes upon pulmonary surfactant in vitro. Am J Respir Cell Mol Biol 1991; 4:33-41.
70. Sawyer DT, Valentine JS. How super is superoxide? Acct Chem Res 1981; 14:393400.
71. Stuehr DJ, Nathan CF. Nitric oxide. A macrophage product responsible for cytosta- sis and respiratory inhibition in tumor target cells. J Exp Med 1989; 169:1543-1555.
72. Tanswell AK, Freeman BA. Pulmonary antioxidant enzyme maturation in the fetal and neonatal rat. I. Developmental profiles. Pediatr Res 1984; 18:584-587.
73. Turrens JF, Freeman BA, Crapo JD. Hyperoxia increases H2O2 release by lung mitochondria and microsomes. Arch Biochem Biophys 1982; 217:411-421.
74. van der Vliet A, Eiserich JP, O’Neill CA, Halliwell B, Cross CE. Tyrosine modification by reactive nitrogen species: a closer look. Arch Biochem Biophys 1995; 319: 341-349.
75. Vara E, Arias-Diaz J, Garcia C, Hernandez J, Balibrea JL. Both prostaglandin-E2 and nitric oxide sequentially mediate the tumor necrosis factor alpha-induced inhibition of surfactant synthesis by human type II pneumocytes. Arch Surg 1995; 130: 1279-1285; see discussion 1286.
76. Warner RL, Paine R 3rd, Christensen PJ, Marletta MA, Richards MK, Wilcoxen SE, Ward PA. Lung sources and cytokine requirements for in vivo expression of inducible nitric oxide synthase. Am J Respir Cell Mol Biol 1995; 12:649-661.
77. Weinbroum A, Nielsen VG, Tan S, Gelman S, Matalon S, Skinner KA, Bradley E Jr, Parks DA. Liver ischemia-reperfusion increases pulmonary permeability in rat: role of circulating xanthine oxidase. Am J Physiol 1995; 268:G988-G996.
78. Wizemann TM, Gardner CR, Laskin JD, Quinones S, Durham SK, Goller NL, Oh- nishi ST, Laskin DL. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia. J Leukoc Biol 1994; 56:759-768.
79. Wright JR, Wager RE, Hamilton RL, Huang M, Clements JA. Uptake of lung surfactant subfractions into lamellar bodies of adult rabbit lungs. J App Physiol 1986; 60: 817-825.
80. Xie K, Huang S, Dong Z, Juang SH, Gutman M, Xie QW, Nathan C, Fidler IJ. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med 1995; 181: 1333-1343.
81. Zhang J, Dawson VL, Dawson TM, Snyder SH. Nitric oxide activation of poly(ADP- ribose) synthetase in neurotoxicity. Science 1994; 263:687-689.
82. Zhu S, Haddad IY, Matalon S. Modification of SP-A mamose-binding properties by reactive oxygen species. Arch Biochem Biophys 1996; 333:282-290.