The absorption characteristics of silybin in small intestine of rat

Yaoxue Xuebao

Volumn 41, Issue 2, 2006, Pages 138-141

  Luan, Li Biao ^a   Zhao, Nuan ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Hepatic portal vein; HPLC; Silybin; Single pass intestinal perfusion

Indexed keywords

SILIBININ; SILYMARIN;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; COLON; DUODENUM; ILEUM; INTESTINE ABSORPTION; ISOLATION AND PURIFICATION; JEJUNUM; MALE; MEDICINAL PLANT; METABOLISM; PERFUSION; RAT; SILYBUM MARIANUM; SMALL INTESTINE; SPRAGUE DAWLEY RAT;

ANIMALS; COLON; DUODENUM; ILEUM; INTESTINAL ABSORPTION; INTESTINE, SMALL; JEJUNUM; MALE; MILK THISTLE; PERFUSION; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; SILYMARIN;

EID: 33645568752     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Lennermas H, Lee ID, Fagerholm M, et al. A residence-time distribution analysis of the hydronamics within the intestine in human during a regional single-pass perfusion with Loc-I-Gut; in vivo permeability estimation [J]. J Pharm Pharmacol, 1997,49:682-686.
2. Curran PF, Solomon AK. Ion and water fluxes in the ileum of rats [J]. J Gen Physiol, 1957,41:143-168.
3. Flora K, Hahn M, Rosen H, et al. Milk thistle (silybum marianum) for the therapy of liver disease [J]. Am J Gastroenterol, 1998,93:139-143.
4. Dackson K, Stone JA, Palin KJ, et al. Evaluation of the mass balance assumption with respect to the two-resistance model of intestinal absorption by using in situ single-pass intestinal perfusion of theophylline in rats [J]. J Pharm Sci, 1992,81:321-325.
5. 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model [J]. AAPS Pharm Sci, 2001,3:E25.
6. You J, Li QB, Yu YW, et al. Absorption of zedoary oil in rat intestine using in situ single pass perfusion model [J]. Acta Pharm Sci, 2004,39:849-853.