Lactic acid bacteria inducing a weak interleukin-12 and tumor necrosis factor alpha response in human dendritic cells inhibit strongly stimulating lactic acid bacteria but act synergistically with gram-negative bacteria

Clinical and Vaccine Immunology

Volumn 13, Issue 3, 2006, Pages 365-375

  Zeuthen, Louise Hjerrild ^a   Christensen, Hanne Risager ^a,b   Frøkiær, Hanne ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENTEROBACTERIACEAE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; INTESTINE FLORA; LACTIC ACID BACTERIUM; MONOCYTE; POLARIZATION; PRIORITY JOURNAL; PROTEIN INDUCTION; STRAIN DIFFERENCE; ULTRAVIOLET RADIATION; UPREGULATION;

BIFIDOBACTERIUM; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; ENTEROBACTERIACEAE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-12; LACTOBACILLUS; LIPOPOLYSACCHARIDES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 33645549167     PISSN: 15566811     EISSN: None     Source Type: Journal    
DOI: 10.1128/CVI.13.3.365-375.2006     Document Type: Article

References (50)

1. Arunachalam, K., H. S. Gill, and R. K. Chandra. 2000. Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019). Eur. J. Clin. Nutr. 54:263-267.
2. Bischoff, S., and S. E. Crowe. 2004. Food allergy and the gastrointestinal tract. Curr. Opin. Gastroenterol. 20:156-161.
3. Bjorksten, B., P. Naaber, E. Sepp, and M. Mikelsaar. 1999. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin. Exp. Allergy 29:342-346.
4. Bjorksten, B., E. Sepp, K. Julge, T. Voor, and M. Mikelsaar. 2001. Allergy development and the intestinal microflora during the first year of life. J. Allergy Clin. Immunol. 108:516-520.
5. Boudeau, J., A. L. Classer, S. Julien, J. F. Colombel, and A. Darfeuille-Michaud. 2003. Inhibitory effect of probiotic Escherichia coli strain Nissle 1917 on adhesion to and invasion of intestinal epithelial cells by adherent-invasive E. coli strains isolated from patients with Crohn's disease. Aliment. Pharm. Ther. 18:45-56.
6. Chiang, B. L., Y. H. Sheih, L. H. Wang, C. K. Liao, and H. S. Gill. 2000. Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses. Eur. J. Clin. Nutr. 54:849-855.
7. Christensen, H. R., H. Frokiaer, and J. J. Pestka. 2002. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol. 168:171-178.
8. Coconnier, M. H., M. F. Bernet, G. Chauviere, and A. L. Servin. 1993. Adhering heat-killed human Lactobacillus acidophilus, strain LB, inhibits the process of pathogenicity of diarrhoeagenic bacteria in cultured human intestinal cells. J. Diarrhoeal. Dis. Res. 11:235-242.
9. Cross, M. L. 2002. Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens. FEMS Immunol. Med. Microbiol. 1442:1-9.
10. Cross, M. L., A. Ganner, D. Teilab, and L. M. Fray. 2004. Patterns of cytokine induction by gram-positive and gram-negative probiotic bacteria. FEMS Immunol. Med. Microbiol. 42:173-180.
11. Cross, M. L., R. R. Mortensen, J. Kudsk, and H. S. Gill. 2002. Dietary intake of Lactobacillus rhamnosus HN001 enhances production of both Th1 and Th2 cytokines in antigen-primed mice. Med. Microbiol. Immunol. 191:49-53.
12. Edwards, C. A., and A. M. Parrett. 2002. Intestinal flora during the first months of life: new perspectives. Br. J. Nutr. 88:S11-S18.
13. Elson, C. O., Y. Z. Cong, N. Iqbal, and C. T. Weaver. 2001. Immune-bacterial homeostasis in the gut: new insights into an old enigma. Semin. Immunol. 13:187-194.
14. Erickson, K. L., and N. E. Hubbard. 2000 Probiotic immunomodulation in health and disease. J. Nutr. 130:403S-409S.
15. Fang, H., T. Elina, A. Heikki, and S. Seppo. 2000. Modulation of humoral immune response through probiotic intake. FEMS immunol. Med. Microbiol. 29:47-52.
16. Fuller, R. 1989. Probiotics in man and animal. J. Appl. Bacteriol. 66:365-378.
17. Geijtenbeek, T. B., S. J. van Vliet, E. A. Koppel, M. Sanchez Hernandez, C. M. J. E. Vandenbroucke-Grauls, B. J. Appelmelk, and Y. van Kooyk. 2005. Mycobacteria target DC-SIGN to suppress dendritic cell function. J. Exp. Med. 197:7-17.
18. Granucci, F., C. Vizzardelli, N. Pavelka, S. Feau, M. Persico, E. Virzi, M. Rescigno, G. More, and P. Ricciardi-Castagnoli. 2001. Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat. Immunol. 2:882-888.
19. Guarner, F., and J. R. Malagelada. 2003. Gut flora in health and disease. Lancet 361:512-519.
20. Hessle, C., B. Andersson, and A. E. Wold. 2000. Gram-positive bacteria are potent inducers of monocytic interleukin-12 (IL-12) while gram-negative bacteria preferentially stimulate IL-10 production. Infect. Immun. 68:3581-3586.
21. Iwasaki, A., and B. L. Kelsall. 1999. Mucosal immunity and inflammation. I. Mucosal dendritic cells: their specialized role in initiating T cell responses. Am. J. Physiol. 276:G1074-G1078.
22. Kalinski, P., C. M. U. Hilkens, E. A. Wierenga, and M. L. Kapsenberg. 1999. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today 20:561-567.
23. Kalliomaki, M., P. Kirjavainen, E. Eerola, P. Kero, S. Salminen, and E. Isolauri. 2001. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J. Allergy Clin. Immunol. 107:129-134.
24. Karlsson, H., C. Hessle, and A. Rudin. 2002. Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect. Immun. 70:6688-6696.
25. Karlsson, H., P. Larsson, A. E. Wold, and A. Rudin. 2004. Pattern of cytokine responses to gram-positive and gram-negative commensal bacteria is profoundly changed when monocytes differentiate into dendritic cells. Infect. Immun. 72:2671-2678.
26. Koppel, E. A., I. S. Ludwig, M. Sanchez Hernandez, T. L. Lowary, R. R. Gadikota, A. B. Tuzikov, C. M. J. E. Vandenbroucke-Grauls, Y. van Kooyk, B. J. Appelmelk, and T. B. H. Geijtenbeek. 2004. Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNRl. Immunobiology 209:117-127.
27. Kruis, W., P. Fric, and M. S. Stolte. 2001. Maintenance of remission in ulcerative colitis is equally effective with Escherichia coli Nissle 1917 and with standard mesalamine. Gastroenterology 120:A127.
28. Ma, D., P. Forsythe, and J. Bienenstock. 2004. Live Lactobacillus reuten is essential for the inhibitory effect on tumor necrosis factor alpha-induced interleukin-8 expression. Infect. Immun. 72:5308-5314.
29. Mack, D. R., S. Michail, S. Wei, L. McDougall, and M. A. Hollingsworth. 1999. Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression. Am. J. Physiol. 276:G941-G950.
30. Malchow, H. A. 1997. Chrohn's disease and Escherichia coli. A new approach in therapy to maintain remission of colonie Crohn's disease? J. Clin. Gastroenterol. 25:653-658.
31. Mohamadzadeh, M., S. Olson, W. V. Kalina, G. Ruthel, G. L. Demmin, K. L. Warfield, S. Bavari, and T. R. Klaenhammer. 2005. Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proc. Natl. Acad. Sci. USA 102:2880-2885.
32. Niess, J. H., S. Brand, X. B. Gu, L. Landsman, S. Jung, B. A. McCormick, J. M. Vyas, M. Boes, H. L. Ploegh, J. G. Fox, D. R. Littman, and H. C. Reinecker. 2005. CX(3)CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307:254-258.
33. Ott, S. J., M. Musfeldt, D. F. Wenderoth, J. Hampe, O. Brant, U. R. Folsch, K. N. Timmis, and S. Schreiber. 2004. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 53:685-693.
34. Rakoff-Nahoum, S., J. Paglino, F. Eslami-Varzaneh, S. Edberg, and R. Medzhitov. 2004. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 118:229-241.
35. Re, F., and J. L. Strominger. 2001. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J. Biol. Chem. 276:37692-37699.
36. Reid, G., and J. Burton. 2002. Use of Lactobacillus to prevent infection by pathogenic bacteria. Microbes Infect. 4:319-324.
37. Rescigno, M. 2002. Dendritic cells and the complexity of microbial infection. Trends Microbiol. 10:425-431.
38. Rigby, R. J., S. C. Knight, M. A. Kamm, and A. J. Stagg. 2005. Production of interleukin (IL)-10 and IL-12 by murine colonie dendritic cells in response to microbial stimuli. Clin. Exp. Immunol. 139:245-256.
39. Satokari, R. M., E. E. Vaughan, H. Smidt, M. Saarela, J. Matto, and W. M. de Vos. 2003. Molecular approaches for the detection and identification of bifidobacteria and lactobacilli in the human gastrointestinal tract. Syst. Appl. Microbiol. 26:572-584.
40. Schiffrin, E. J., and S. Blum. 2002. Interactions between the microbiota and the intestinal mucosa. Eur. J. Clin. Nutr. 56:S60-S64.
41. Shanahan, F. 2002. Crohn's disease. Lancet 359:62-69.
42. Smits, H. H., A. J. van Beelen, C. Hessle, R. Westland, E. de Jong, E. Soeteman, A. Wold, E. A. Wierenga, and M. L. Kapsenberg. 2004. Commensal gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur. J. Immunol. 34:1371-1380.
43. Smits, H. H., E. C. de Jong, E. A. Wierenga, and M. L. Kapsenberg. 2005. Different faces of regulatory DCs in homeostasis and immunity. Trends Immunol. 26:123-129.
44. Smits, H. H., A. Engering, D. van der Kleij, E. C. de Jong, K. Schipper, T. M. M. van Capel, B. A. J. Zaat, M. Yazdanbakhsh, E. A. Wierenga, Y. van Kooyk, and M. L. Kapsenberg. 2005. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J. Allergy Clin. Immunol. 115:1260-1267.
45. Underhill, D. M., and A. Ozinsky. 2002. Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14:103-110.
46. van Kooyk, Y., and T. B. H. Geijtenbeek. 2003. DC-sign: escape mechanism for pathogens. Nat. Rev. Immunol. 3:697-709.
47. Vaughan, E. E., M. C. de Vries, E. G. Zoetendal, K. Ben Amor, A. D. L. Akkermans, and W. M. de Vos. 2002. The intestinal LABs. Antonie Leeuwenhoek 82:341-352.
48. Viney, J. L., A. M. Mowat, J. M. O'Malley, E. Williamson, and N. A. Fanger. 1998. Expanding dendritic cells in vivo enhances the induction of oral tolerance. J. Immunol. 160:5815-5825.
49. Wills-Karp, M., J. Santeliz, and C. L. Karp. 2001. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat. Rev. Immunol. 1:69-75.
50. + dendritic cells. Proc. Natl. Acad. Sci. USA 93:2588-2592.