Protection and mechanism of notoginsenoside-Rg1 on focal cerebral ischemia-reperfusion rats

Chinese Traditional and Herbal Drugs

Volumn 37, Issue 2, 2006, Pages 229-233

  Wu, Lan Ou ^a   Zhan, He Qin ^a   Yan, Jun Ling ^a   Cai, Wen Feng ^a   Wu, Jin Ping ^a   Yang, Ke Hong ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Brain derived neurotrophic factor (BDNF); Cerebral ischemia reperfusion; Notoginsenoside Rg1

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GINSENOSIDE RG 1; NIMODIPINE;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL COUNT; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FROZEN SECTION; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RAT STRAIN; REGULATORY MECHANISM; REPERFUSION INJURY; SYMPTOM; TISSUE SECTION; UPREGULATION;

EID: 33645547274     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Zhang J T. The Progress of Study on Neuropharmacology [M]. Beijing: People's Medical Publishing House, 2002.
2. Hou A H. Clinical application and experimental study of pseudoginseng [J]. Inf Tradit Chin Med, 1999, 16(6): 21-24.
3. Liu J H, Ji F Y, Wang T, et al. Study on protective effects of Panax notoginseng saponins on brain ischemic reperfusion damage [J]. Chin J Clin Neurosci, 2002, 10(1): 90.
4. 1 on some central neurotransmitter receptors and protein biosynthesis in mouse brain [J]. Acta Pharm Sin, 1988, 23(1): 12-16.
5. Longa E Z, Weistein P R, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rat [J]. Stroke, 1989, 20(1): 84-91.
6. Xu S Y, Bian R L, Chen X, et al. Methodology in Pharmacol Experiment [M]. 3rd ed. Beijing: People's Medical Publishing House, 2002.
7. Zeng J, Wang T H, Zhang X, et al. The change of nerve growth factor and brain derived neurotrophic factor in neurons of cerebral cortex of adult rat following local ischemia [J]. Acta Univ Med West China 2001, 32(2): 216-217.
8. Endres M, Fan G, Hirt L, et al. Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression [J]. J Cereb Blood Flow Metab, 2000, 20(1): 139-144.
9. Larsson E, Nanobashvili A, Kokaia Z, et al. Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats [J]. J Cereb Blood Flow Metab, 1999, 19(11): 1220-1228.
10. Kiprionova I, Sandkuhler J, Schwab S, et al. Brain-derived neurotrophic factor improves long-term potentiation and cognitive functions after transient forebrain ischemia in the rat [J]. Exp Neurol, 1999, 159(2): 511-519.
11. 1 neurons following transient forebrain ischemia [J]. Brain Pathol, 1998, 8(2): 253-261.
12. Cheng B, Matton M P. NT-3 and BDNF Protect CNS neurons against metabolic/excitotoxic insults [J]. Brain Res, 1994, 640(1-2): 56-67.
13. Lindvall O, Kokaia Z, Bengzen J, et al. Neurotrophins and brain insults [J]. Trends Neurons CI, 1994, 17: 490-496.
14. Hee Han B, D'Coast A, Back S A, et al. BDNF Blocks caspase-3 activation in neuratal hypoxia-ischemia [J]. Neurobid Dis, 2000, 7(1), 38-53.
15. Sauer H, Fischer W, Nikkhah G, et al. Brain-derived neurotrophic factor enhances function rather than survival of in trastriatal dopamine cell-rich grafts [J]. Brain Res, 1993, 626(12): 37.
16. Zheng G Z, Yang C R. Biology and Application of Panax notoginseng [M]. Beijing: Science Press, 1994.