Summary: Systemic effects of inhaled nitric oxide

Proceedings of the American Thoracic Society

Volumn 3, Issue 2, 2006, Pages 170-172

  Gaston, Benjamin ^a  

^a UNIVERSITY OF VIRGINIA CHILDREN S HOSPITAL   (United States)

Author keywords

Circulation; Nitric oxide; S nitrosothiol

Indexed keywords

GUANYLATE CYCLASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

BLOOD FLOW; BLOOD VESSEL; CONFERENCE PAPER; DRUG EFFECT; ENZYME INHIBITION; HUMAN; ISCHEMIA; LEUKOCYTE ADHERENCE; LUNG INJURY; REPERFUSION INJURY;

ADMINISTRATION, INHALATION; ANIMALS; HUMANS; NITRIC OXIDE; RESPIRATORY PHYSIOLOGY; S-NITROSOTHIOLS; VASODILATOR AGENTS;

EID: 33645516346     PISSN: 15463222     EISSN: 15463222     Source Type: Journal    
DOI: 10.1513/pats.200506-049BG     Document Type: Conference Paper

References (25)

1. Taylor R, Zimmerman J, Dellinger R, Straube R, Criner G, Davis K Jr, Kelly K, Smith T, Small R, for the Inhaled Nitric Oxide in ARDS Study Group. Low-dose inhaled nitric oxide in patients with acute lung injury. JAMA 2004;291:1603-1609.
2. Dellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL, Griner GJ, Davis K Jr, Hyers TM, Papadakos P. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Crit Care Med 1998;26:15-23.
3. Lundin S, Mang H, Smithies M, Stenqvist O, Frostell C, for the European Study Group of Inhaled Nitric Oxide. Inhalation of nitric oxide in acute lung injury. Intensive Care Med 1999;25:911-919.
4. Gaston B, Stamler JS. Nitrogen oxides and lung function. In: Crystal R, West J, Weibel E, Barnes P, editors. The lung: scientific foundations, 2nd ed. Philadelphia: Lippincott Raven; 1997. pp 239-253.
5. Troncy E, Francœur M, Salazkin I, Yang F, Charbonneau M, Leclerc G, Vinay P, Blaise G. Extra-pulmonary effects of inhaled nitric oxide in swine with and without phenylephrine. Br J Anaesth 1997;79:631-640.
6. Fox-Robichaud A, Payne D, Hasan S, Ostrovsky L, Fairhead T, Reinhardt P, Kubes P. Inhaled NO as a viable antiadhesive therapy for ischemia/reperfusion injury of distal microvascular beds. J Clin Invest 1998;101:2497-2505.
7. Fox-Robichaud A, Payne D, Kubes P. Inhaled NO reaches distal vasculatures to inhibit endothelium-but not leukocyte-dependent cell adhesion. Am J Physiol Lung Cell Mol Physiol 1999;277:1224-1231.
8. Kubes P, Payne D, Grisham MB, Jourd'heuil D, Fox-Robichaud A. Inhaled NO impacts vascular but not extravascular compartments in postischemic peripheral organs. Am J Physiol 1999;277:676-682.
9. Ng E, Jourd'heuil D, McCord J, Hernandez D, Yasui M, Knight D, Kubes P. Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/ reperfusion. Circ Res 2004;94:559-565.
10. Sonveaux P, Kaz A, Snyder S, Richardson R, Cárdenas-Navia L, Braun R, Pawloski J, Tozer G, Bonaventura J, McMahon T, et al. Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide. Circ Res 2005;96:1119-1126.
11. Palmer L, Chhabra P, Doctor A, Sheram M, Laubach V, Gaston B. N-acetyl cysteine induces pulmonary hypertension: role of S-nitrosothiols [abstract]. Proc Am Thorac Soc 2005;2:A707.
12. Lipton A, Johnson M, Macdonald T, Lieberman M, Gozal D, Gaston B. S-Nitrosothiols signal the ventilatory response to hypoxia. Nature 2001;413:171-174.
13. 2 gradients. Proc Natl Acad Sci USA 2005;102:5709-5714.
14. Pawloski JR, Hess DT, Stamler JS. Export by red blood cells of nitric oxide bioactivity. Nature 2001;409:622-626.
15. Rogers S, Khalatbari A, Gapper P, Frenneaux M, James P. Detection of human red blood cell-bound nitric oxide. J Biol Chem 2005;280:26720-26728.
16. Gianetti J, Del Sarto P, Bevilacqua S, Vassalle C, De Filippis R, Kacila M, Farneti PA, Clerico A, Glauber M, Biagini A. Supplemental nitric oxide and its effect on myocardial injury and function in patients undergoing cardiac surgery with extracorporeal circulation. J Thorac Cardiovasc Surg 2004;127:44-50.
17. Loh E, Stamler JS, Hare JM, Loscalzo J, Colucci WS. Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction. Circulation 1994;90:2780-2785.
18. Loh E, Lankford EB, Polidori DJ, Doering-Lubit EB, Hanson CW, Acker MA. Cardiovascular effects of inhaled nitric oxide in a canine model of cardiomyopathy. Ann Thorac Surg 1999;67:1380-1385.
19. Barouch L, Harrison R, Skaf M, Rosas G, Cappola T, Kobeissi Z, Hobal I, Lemmon C, Burnett A, O'Rourke B, et al. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature 2002;416:337-340.
20. Ohta H, Bates JN, Lewis SJ, Talman WT. Actions of S-nitrosocysteine in the nucleus tractus solitarii are unrelated to release of nitric oxide. Brain Res 1997;746:98-104.
21. Zhang Y, Hogg N. The mechanism of transmembrane S-nitrosothiol transport. Proc Natl Acad Sci USA 2004;101:7891-7896.
22. Mannick J, Schonhoff C, Papeta N, Ghafourifar P, Szibor M, Fang K, Gaston B. S-nitrosylation of mitochondrial caspases. J Cell Biol 2001;154:1111-1116.
23. Hogman M, Frostell C, Arnberg H, Sandhagen B, Hedenstierna G. Prolonged bleeding time during nitric oxide inhalation in the rabbit. Acta Physiol Scand 1994;151:125-129.
24. Mestan KKL, Marks JD, Hecox K, Huo D, Schreiber MD. Neurodevelopmental outcomes of premature infants treated with inhaled nitric oxide. N Engl J Med 2005;353:23-32.
25. Jaffrey SR, Erdjument-Bromage H, Ferris CD, Tempst P, Snyder SH. Protein S-nitrosylation: a physiological signal for neuronal nitric oxide. Nat Cell Biol 2001;3:193-197.