Changes in properties of substantia gelatinosa neurons after surgical incision in the rat: In vivo patch-clamp analysis

Anesthesiology

Volumn 104, Issue 3, 2006, Pages 432-440

  Kawamata, Mikito ^a   Furue, Hidemasa ^b   Kozuka, Yuji ^a   Narimatsu, Eichi ^a   Yoshimura, Megumu ^b   Namiki, Akiyoshi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LIDOCAINE; URETHAN;

ACTION POTENTIAL; ANIMAL EXPERIMENT; CONFERENCE PAPER; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; INCISION; NERVE CELL; NOCICEPTION; NONHUMAN; PAIN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SUBSTANTIA GELATINOSA; ANIMAL; ARTICLE; EVOKED RESPONSE; MALE; MYELINATED NERVE; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTOPERATIVE PAIN; SPRAGUE DAWLEY RAT; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; EVOKED POTENTIALS; LIDOCAINE; MALE; NERVE FIBERS, MYELINATED; PAIN, POSTOPERATIVE; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA GELATINOSA; SYNAPTIC TRANSMISSION;

EID: 33645509124     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/00000542-200603000-00009     Document Type: Conference Paper

References (40)

1. Kehlet H, Holte K: Effect of postoperative analgesia on surgical outcome. Br J Anaesth 2001; 87:62-72
2. Brennan TJ, Zahn PK, Pogatzki-Zahn EM: Mechanisms of incisional pain. Anesthesiol Clin North Am 2005; 23:1-20
3. Mantyh PW: A mechanism based understanding of cancer pain. Pain 2002; 96:1-2
4. Brennan TJ, Vandermeulen EP, Gebhart GF: Characterization of a rat model of incisional pain. Pain 1996; 64:493-501
5. Pogatzki EM, Raja SN: A mouse model of incisional pain. ANESTHESIOLOGY 2003; 99:1023-7
6. Kawamata M, Koshizaki M, Shimada SG, Narimatsu E, Kozuka Y, Takahashi T, Namiki A, Collins JG: Changes in response properties and receptive fields of spinal dorsal horn neurons in rats after surgical incision in hairy skin. ANESTHESIOLOGY 2005; 102:141-51
7. Duarte AM, Pospisilova E, Reilly E, Mujenda F, Hamaya Y, Strichartz GR: Reduction of postincisional allodynia by subcutaneous bupivacaine: Findings with a new model in the hairy skin of the rat. ANESTHESIOLOGY 2005; 103:113-25
8. Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD: Neurogenic hyperalgesia: Central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol 1991; 66:228-46
9. Hoheisel U, Mense S: Long-term changes in discharge behavior of cat dorsal horn neurons following stimulation of deep tissue. Pain 1989; 36:239-47
10. Woolf CJ, King AE: Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord. J Neurosci 1990; 10:2717-26
11. Pogatzki EM, Vandermeulen EP, Brennan TJ: Effects of plantar local anesthetic injection on dorsal horn neuron activity and pain behaviors caused by incision. Pain 2002; 97:151-61
12. Zahn PK, Pogatzki-Zahn EM, Brennan TJ: Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incision pain. Pain 2005; 114:499-510
13. Zahn PK, Brennan TJ,: Incision-induced changes in receptive field properties of rat dorsal horn neurons. ANESTHESIOLOGY 1999; 91:772-85
14. Light AR, Perl ER: Re-examination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol 1979; 186:117-32
15. Cervero F, Iggo A: The substantia gelatinosa of the spinal cord. A critical review. Brain 1980; 103:717-72
16. Eckert WA, 3rd McNaughton KK, Light AR: Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by mu-opioid-selective agonists. J Comp Neurol 2003; 458:240-56
17. Yoshimura M: Slow synaptic transmission in the spinal dorsal horn. Prog Brain Res 1996; 113:443-62
18. Nakatsuka T, Park JS, Kumamoto E, Tamaki T, Yoshimura M: Plastic changes in sensory inputs to rat substantia gelatinosa neurons following peripheral inflammation. Pain 1999; 82:39-47
19. Okamoto M, Baba H, Goldstein PA, Higashi H, Shimoji K, Yoshimura M: Functional reorganization of sensory pathways in the rat spinal dorsal horn following peripheral nerve injury. J Physiol 2001; 532:241-50
20. Furue H, Katafuchi T, Yoshimura M: Sensory processing and functional reorganization of sensory transmission under pathological conditions in the spinal dorsal horn. Neurosci Res 2004; 48:361-8
21. Furue H, Narikawa K, Kumamoto E, Yoshimura M: Responsiveness of rat substantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. J Physiol 1999; 521:529-35
22. Zimmermann M: Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983; 16:109-10
23. Sonohata M, Furue H, Katafuchi T, Yasaka T, Doi A, Kumamoto E, Yoshimura M: Actions of noradrenaline on substantia gelatinosa neurons in the rat spinal cord revealed by in vivo patch recording. J Physiol 2004; 555:515-26
24. Yoshimura M, Nishi S: Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: Pharmacological properties of synaptic currents. Neuroscience 1993; 53:519-26
25. Woolf CJ, Fitzgerald M: The properties of neurones recorded in the superficial dorsal horn of the rat spinal cord. J Comp Neurol 1983; 221:313-28
26. Rethelyi M, Light AR, Perl ER: Synaptic ultrastructure of functionally and morphologically characterized neurons of the superficial spinal dorsal horn of cat. J Neurosci 1989; 9:1846-63
27. Light AR, Willcockson HH: Spinal laminae I-II neurons in rat recorded in vivo in whole cell, tight seal configuration: properties and opioid responses. J Neurophysiol 1999; 82:3316-26
28. Graham BA, Brichta AM, Callister RJ: In vivo responses of mouse superficial dorsal horn neurones to both current injection and peripheral cutaneous stimulation. J Physiol 2004; 561:749-63
29. Narikawa K, Furue H, Kumamoto E, Yoshimura M: In invo patch-clamp analysis of IPSCs evoked in rat substantia gelatinosa neurons by cutaneous mechanical stimulation. J Neurophysiol 2000; 84:2171-4
30. Pogatzki EM, Gebhart GF, Brennan TJ: Characterization of Adelta- and C-fibers innervating the plantar rat hindpaw one day after an incision. J Neurophysiol 2002; 87:721-31
31. Kozuka Y, Kawamata M, Narimatsu E, Niiya T, Namiki A: Plasticity of superficial dorsal horn neurons after acute spinal cord hemisection in rats by analysis using in vivo whole-cell patch-clamp recording (abstract). ANESTHESIOLOGY 2005; 103:A1103
32. Bartlett EE, Hutserani O: Xylocaine for the relief of postoperative pain. Anesth Analg 1961; 40:296-304
33. Cassuto J, Wallin G, Hogstrom S, Faxen A, Rimback G: Inhibition of postoperative pain by continuous low-dose intravenous infusion of lidocaine. Anesth Analg 1985; 64:971-4
34. Koppert W, Weigand M, Neumann F, Sittl R, Schuettler J, Schmelz M, Hering W: Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery. Anesth Analg 2004; 98:1050-5
35. Kawamata M, Takahashi T, Kozuka Y, Nawa Y, Nishikawa K, Narimatsu E, Watanabe H, Namiki A: Experimental incision-induced pain in human skin: Effects of systemic lidocaine on flare formation and hyperalgesia. Pain 2002; 100:77-89
36. Abram SE, Yaksh TL: Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat. ANESTHESIOLOGY 1994; 80:383-91
37. Puig S, Sorkin LS: Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain 1996; 64:345-55
38. Taylor BK, Peterson MA, Basbaum AI: Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input. J Neurosci 1995; 15:7575-84
39. Omana-Zapata I, Khabbaz MA, Hunter JC, Bley KR: QX-314 inhibits entopic nerve activity associated with neuropathic pain. Brain Res 1997; 771:228-37
40. Kawamata M, Takahashi T, Narimatsu E, Niiya T, Namiki A: Effects of systemic administration of lidocaine and QX-314 on hyperexcitability of spinal dorsal horn neurons after incision in the rat (abstract). ANESTHESIOLOGY 2005; 103:A1483