Dry granulation and compression of spray-dried plant extracts

AAPS PharmSciTech

Volumn 6, Issue 3, 2005, Pages

  Soares, Luiz Alberto Lira ^a,b   González Ortega, George ^b   Petrovick, Pedro Ros ^b   Schmidt, Peter Christian ^c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Dry granulation; Heckel plot; Maytenus ilicifolia; Spray dried extracts; Tableting

Indexed keywords

AEROSIL; CARBOXYMETHYLCELLULOSE; MAGNESIUM STEARATE; MAYTENUS ILICIFOLIA EXTRACT; MICROCRYSTALLINE CELLULOSE; PLANT EXTRACT; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG GRANULATION; HERBAL MEDICINE; MATHEMATICAL COMPUTING; MAYTENUS; NONHUMAN; PARTICLE SIZE; PHYSICAL PARAMETERS; POWDER; PRESSURE MEASUREMENT; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; STOMACH DISEASE; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET HARDNESS; CHEMISTRY; COMPRESSIVE STRENGTH; METHODOLOGY; PHARMACEUTICS; PLANT; SYNTHESIS; TABLET;

COMPRESSIVE STRENGTH; MAYTENUS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 33645506506     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060345     Document Type: Article

References (25)

1. De Souza KCB, Petrovick PR, Bassani VL, González Ortega G. The adjuvants Aerosil 200 and Gelita-Sol-P influence on the technological characteristics of spray-dried powder from Passiflora edulis var. flavicarpa. Drug Dev Ind Pharm. 2000;26:331-336.
2. Diaz L, Souto C, Concheiro A, Gomez-Amozy LM, Martinez-Pacheco R. Evaluation of Eudragit E as excipient in tablets of dry plant extract. STP Pharma Sci. 1986;2:105-109.
3. De Souza TP, Bassani VL, González Ortega G, Dalla Costa TCT, Petrovick PR. Influence of adjuvants on the dissolution profile of tablets containing high dose of spray-dried extract of Maytenus ilicifolia. Pharmazie. 2001;56:730-733.
4. Plaizer-Vercamen JA, Bruwier C. Evaluation of excipients for direct compression of the spray-dried extract of Harpogaphytum procumbens. STP Pharma Sci. 1986:2:525-530.
5. Rocksloh K, Rapp FR, Abu Abed S, et al. Optimization of crushing strength and disintegration time of a high-dose plant extract tablet by neural network. Drug Dev Ind Pharm. 1999,25:1015-1025.
6. Von Eggelkraut-Gottanka SG, Abu Abeb S, Müller W, Schmidt PC. Roller compaction and tabletting of St. John's wort plant dry extract using gap width and force controlled roller compactor, I: granulation and tabletting of eight different extract batches. Pharm Dev Technol. 2002;7:433-445.
7. Miller RW. Roller compaction technology. In: Parikh DM, ed. Handbook of Pharmaceutical Granulation Technology. New York, NY: Marcel Dekker; 1997:99-150.
8. Freitag F, Kleinebude P. How do roll compaction/dry granulation affect the tablet behavior of inorganic materials? Comparison of four magnesium carbonates. Eur J Pharm Sci. 2003;19:281-289.
9. Bultmann JM. Multiple compaction of microcrystalline cellulose in a roller compactor. Eur J Pharm Biopharm. 2002:54:59-64.
10. Heckel RW. An analysis of powder compaction phenomena. Trans. Metal. Sci. AIME 1961;221:1001-1008.
11. Heckel RW. Density-pressure relationship in powder compaction. Trans. Metal. Sci. AIME 1961;221:671-675.
12. Rue PJ, Rees JE. Limitations of the Heckel relation for predicting powder compaction mechanisms. J Pharm Pharmacol. 1978;30:642-643.
13. Ilkka J, Paronen P. Prediction of the compression behavior of powder mixtures by the Heckel equation. Int J Pharm. 1993;94:181-187.
14. Mitrevej A, Faroongsarng D, Sinchaipanid N. Compression behavior of spray dried starch. Int J Pharm. 1996;140:61-68.
15. Kochhar SK, Rubinstein MH, Barnes D. The effects of slugging and recompression on pharmaceutical excipients. Int J Pharm. 1995;115:35-43.
16. Horisawa E, Danjo K, Sunada H. Influence of granulating method on physical and mechanical properties: compression behavior and compactibility of lactose and microcrystalline cellulose granules. Drug Dev Ind Pharm. 2000;26:583-593.
17. Petrovick PR, Carlini E, inventors. Antiulcerogenic preparation from Maytenus ilicifolia and obtainment process. Brazil patent PI 994 502. March 6, 1999.
18. DIN 66145. Darstellung von Korn-(teilchen-)grössenverteilungen - RRSB-Netz. In: DIN Deutsches Institut für Normung. DIN-Taschenbuch 133 - Partikelmesstechnik: Normen. Berlin, Germany: Beuth Verlag; 1997:191-193.
19. European Pharmacopoeia. Strasbourg, France: Council of Europe; 1997.
20. Hausner HH. Friction conditions in a mass of metal powder. Int J Powder Mettall. 1967;3:7-13.
21. Carr RL. Evaluating flow properties of solids. Chem Engineer. 1965;72:163-168.
22. Guyot JC, Arnaud P, Becourt P, et al. Commentaires Relatifs aux Méthodes Générales d'analyse des Formes Orales Solides Récemment Introduites dans les Pharmacopées Française et Européene. Rapport d'une Commision SFSTP. STP Pharma Pratiques. 1995;5:482-494.
23. Dressler JA, Wagner KG, Wahl MA, Schmidt PC. Comparison of incremental and inductive displacement transducers on an eccentric tablet press. Pharm Ind. 2001;53:886-893.
24. European Pharmacopoeia Supplement. Strasbourg, France: Council of Europe; 2001.
25. Rees JE, Rue PJ. Time-dependent deformation of some direct compression excipient. J Pharm Pharmacol. 1978;30:601-607.