Thyroid hormones and 3,5-diiodothyropropionic acid: New keys for new locks

Endocrinology

Volumn 147, Issue 4, 2006, Pages 1598-1601

  Yen, Paul M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 IODOTHYRONAMINE; 3,5 DIBROMO 3 PYRIDAZINONE L THYRONINE; 3,5 DIIODOTHYROPROPIONIC ACID; ACETIC ACID DERIVATIVE; ADENOSINE TRIPHOSPHATASE (CALCIUM); BENZENE DERIVATIVE; BINDING PROTEIN; CGS 23425; GC 1; HISTONE DEACETYLASE; INTEGRIN; IODINE DERIVATIVE; KB 141; L 940901; LAMININ; LIOTHYRONINE; NUCLEAR RECEPTOR COREPRESSOR; PROPIONIC ACID DERIVATIVE; PROTEIN P160; RNA POLYMERASE II; SCLEROPROTEIN; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYRONINE DERIVATIVE; THYROXINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

CELL DIFFERENTIATION; CELL GROWTH; CELL METABOLISM; CHOLESTEROL BLOOD LEVEL; DRUG STRUCTURE; ENZYME ACTIVATION; HEART PERFORMANCE; HORMONE BINDING; HUMAN; HYPERCHOLESTEROLEMIA; HYPOTHYROIDISM; IMMUNOPRECIPITATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; REVIEW; RNA SYNTHESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; DIIODOTHYRONINES; HUMANS; INTEGRIN ALPHAVBETA3; NEOVASCULARIZATION, PHYSIOLOGIC; PROPIONIC ACIDS; RESPONSE ELEMENTS; THYROID HORMONES;

EID: 33645501367     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0074     Document Type: Review

References (34)

1. Yen PM 2001 Physiological and molecular basis of thyroid hormone action. Physiol Rev 81:1097-1142
2. Bassett JH, Harvey CB, Williams GR 2003 Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions. Mol Cell Endocrinol 213:1-11
3. Tata JR, Widnell CC 1966 Ribonucleic acid synthesis during the early action of thyroid hormones. Biochem J 98:604-629
4. Samuels HH, Tsai JS 1973 Thyroid hormone action in cell culture: Demonstration of nuclear receptors in intact cells and isolated nuclei. Proc Natl Acad Sci USA 70:3488-3492
5. Oppenheimer JH, Koerner D, Schwartz HL, Surks MI 1972 Specific nuclear triiodothyronine binding sites in rat liver and kidney. J Clin Endocrinol Metab 35:330-333
6. Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, Evans RM 1986 The c-erbA gene encodes a thyroid hormone receptor. Nature 324:641-646
7. Sap J, Munoz A, Damm K, Goldberg Y, Ghysdael J, Leutz A, Beug H, Vennstrom B 1986 The c-erbA protein is a high affinity receptor for thyroid hormone. Nature 324:635-640
8. Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103:843-852
9. Reid G, Hubner MR, Metivier R, Brand H, Denger S, Manu D, Beaudouin J, Ellenberg J, Gannon F 2003 Cyclic, proteasome-mediated turnover of unliganded and liganded ERα on responsive promoters is an integral feature of estrogen signaling. Mol Cell 11:695-707
10. Liu Y, Xia X, Fondell JD, Yen PM 2006 Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. Mol Endocrinol 20:483-490
11. Davis PJ, Davis FB, Cody V 2005 Membrane receptors mediating thyroid hormone action. Trends Endocrinol Metab 16:429-435
12. Baumann CT, Maruvada P, Hager GL, Yen PM 2001 Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retention. J Biol Chem 276:11237-11245
13. Davis PJ, Davis FB 1996 Nongenomic actions of thyroid hormone. Thyroid 6:497-504
14. Cheng SY, Gong QH, Parkison C, Robinson EA, Appella E, Merlino GT, Pastan I 1987 The nucleotide sequence of a human cellular thyroid hormone binding protein present in endoplasmic reticulum. J Biol Chem 262:11221-11227
15. Kato H, Fukuda T, Parkison C, McPhie P, Cheng SY 1990 Cytoplasmic thyroid hormone-binding protein is a monomer of pyruvate kinase. Proc Natl Acad Sci USA 86:7681-7685
16. Sterling K, Brenner MA 1995 Thyroid hormone action: effect of triiodothyronine on mitochondrial adenine nucleotide translocase in vivo and in vitro. Metabolism 44:193-199
17. Wrutniak C, Cassar-Malek I, Marchal, Rascle SA, Heusser S, Keller JM, Flechon J, Dausca M, Samarut J, Ghysdael J 1995 A 43 kD protein related to c-erb Aα1 is located in the mitochondrial matrix of rat liver. J Biol Chem 270:16347-16354
18. Bergh JJ, Lin HY, Lansing L, Mohamed SN, Davis FB, Mousa S, Davis PJ 2005 Integrin αVβ3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology 146:2864-2871
19. Farwell AP, Tranter MP, Leonard JL 1995 Thyroxine-dependent regulation of integrin-laminin interactions in astrocytes. Endocrinology 136:3909-3915
20. Underwood AH, Emmett JC, Ellis D, Flynn SB, Leeson PD, Benson GM, Novelli R, Pearce NJ, Shah VP 1986 A thyromimetic that decreases plasma cholesterol levels without increasing cardiac activity. Nature 324:425-429
21. Friesema EC, Ganguly S, Abdalla A, Manning Fox JE, Halestrap AP, Visser TJ 2003 Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J Biol Chem 278:40128-40135
22. Shi YB, Ritchie JW, Taylor PM 2002 Complex regulation of thyroid hormone action: multiple opportunities for pharmacological intervention. Pharmacol Ther 94:235-251
23. Taylor AH, Stephan ZF, Steele RE, Wong NC1997 Beneficial effects of a novel thyromimetic on lipoprotein metabolism. Mol Pharmacol 52:542-547
24. Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS 1998 A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chem Biol 5:299-306
25. Grover GJ, Mellstrom K, Ye L, Malm J, Li YL, Bladh LG, Sleph PG, Smith MA, George R, Vennstrom B, Mookhtiar K, Horvath R, Speelman J, Egan D, Baxter JD 2003 Selective thyroid hormone receptor-β activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability. Proc Natl Acad Sci USA 100:10067-10072
26. Johansson L, Rudling M, Scanlan TS, Lundasen T, Webb P, Baxter J, Angelin B, Parini P 2005 Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice. Proc Natl Acad Sci USA 102:10297-10302
27. Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S, Lin ET, Hatton, D, Zucchi R, Grandy, DK 2004 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. Nat Med 10:638-662
28. Morkin E, Ladenson P, Goldman S, Adamson C 2004 Thyroid hormone analogs for treatment of hypercholesterolemia and heart failure: past, present and future prospects. J Mol Cell Cardiol 37:1137-1146
29. Morkin E, Pennock GD, Spooner PH, Bahl JJ, Goldman S 2002 Clinical and experimental studies on the use of 3,5-diiodothyropropionic acid, a thyroid hormone analogue, in heart failure. Thyroid 12:527-533
30. Mousa SA, O'Connor L, Davis FB, Davis PJ 2006 Proangiogenesis action of the thyroid hormone analog 3,5-diiodothyropropionic acid (DITPA) is initiated at the cell surface and is integrin mediated. Endocrinology 147:1602-1607
31. Tomanek RJ, Zimmerman MB, Suvarna PR, Morkin E, Pennock GD, Goldman S 1998 A thyroid hormone analog stimulates angiogenesis in the post-infarcted rat heart. J Mol Cell Cardiol 30:923-932
32. Mousa SA, O'Connor LJ, Bergh JJ, Davis FB, Scanlan TS, Davis PJ 2005 The proangiogenic action of thyroid hormone analogue GC-1 is initiated at an integrin. J Cardiovasc Pharmacol 46:356-360
33. Cao X, Kambe F, Moeller LC, Refetoff S, Seo H 2005 Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol Endocrinol 19:102-112
34. Moeller LC, Dumitrescu AM, Refetoff S 2005 Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1α and glycolytic genes. Mol Endocrinol 19:2955-2963