Hemodialysis vascular access dysfunction: A cellular and molecular viewpoint

Journal of the American Society of Nephrology

Volumn 17, Issue 4, 2006, Pages 1112-1127

  Roy Chaudhury, Prabir ^a,d   Sukhatme, Vikas P ^b   Cheung, Alfred K ^c  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF UTAH   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID PLUS DIPYRIDAMOLE; ANTIBODY; CD34 ANTIBODY; CLOPIDOGREL; CYCLIN DEPENDENT KINASE INHIBITOR; DIPYRIDAMOLE; EDIFOLIGIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FISH OIL; INDUCIBLE NITRIC OXIDE SYNTHASE; PACLITAXEL; POLYMER; RAPAMYCIN; RECOMBINANT PROTEIN; RETINOBLASTOMA PROTEIN; ROSIGLITAZONE; SCATTER FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ANGIOPLASTY; ARTERIOVENOUS FISTULA; BIOLOGICAL THERAPY; BLOOD VESSEL GRAFT; BONE MARROW CELL; CATHETER; CELL BASED THERAPY; CELL TRANSPLANTATION; CLINICAL TRIAL; CRYOPLASTY; CRYOTHERAPY; DRUG ADMINISTRATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG ELUTING STENT; DRUG MECHANISM; ENDOTHELIUM CELL; ENDOTHELIUM CELL SEEDING; GENE THERAPY; GENETIC MANIPULATION; GRAFT FAILURE; HEMODIALYSIS; HUMAN; HYPERPLASIA; NONHUMAN; PERIVASCULAR DRUG ADMINISTRATION; PHOTODYNAMIC THERAPY; POLITEF IMPLANT; PRIORITY JOURNAL; RADIOTHERAPY; REVIEW; STEM CELL; STENOSIS; STENT; STENT GRAFT; VASCULAR ACCESS; VASCULAR ACCESS DYSFUNCTION; VEIN INTIMA HYPERPLASIA; VEIN OCCLUSION; VEIN STENOSIS;

EID: 33645468474     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2005050615     Document Type: Review

References (122)

1. United States Renal Data System: 2002 Annual Data Report, Bethesda, National Institutes of Health, National Institute of Diabetes and Digestive Diseases, 2002
2. Feldman HI, Kobrin S, Wasserstein A: Hemodialysis vascular access morbidity. J Am Soc Nephrol 7: 523-535, 1996
3. Egger P: Trends in Medicare Expenditure for Vascular Access. Presented at the Cincinnati Hemodialysis Vascular Access Symposium, March 19, 2004
4. Schwab SJ, Harrington JT, Singh A, Roher R, Shohaib S, Perrone R, Meyer K, Beasley D: Vascular access for hemodialysis. Kidney Int 55: 2078-2090, 1999
5. Miller PE, Tolwani A, Luscy CP, Deierhoi MH, Bailey R, Redden DT, Allon M: Predictors of adequacy of arteriovenous fistulas in hemodialysis patients. Kidney Int 56: 275-280, 1999
6. Hodges TC, Fillinger MF, Zwolak RM, Walsh DB, Bech F, Cronenwett JL: Longitudinal comparison of dialysis access methods: Risk factors for failure. J Vasc Surg 26: 1009-1019, 1997
7. Leapman SB, Boyle M, Pescovitz MD, Milgrom ML, Jindal RM, Filo RS: The arteriovenous fistula for hemodialysis access: Gold standard or archaic relic? Am Surg 62: 652-656; discussion 656-657, 1996
8. Beasley C, Rowland J, Spergel L: Fistula first: An update for renal providers. Nephrol News Issues 18: 88, 90, 2004
9. Miller PE, Carlton D, Deierhoi MH, Redden DT, Allon M: Natural history of arteriovenous grafts in hemodialysis patients. Am J Kidney Dis 36: 68-74, 2000
10. Turmel-Rodrigues L, Pengloan J, Baudin S, Testou D, Abaza M, Dahdah G, Mouton A, Blanchard D: Treatment of stenosis and thrombosis in haemodialysis fistulas and grafts by interventional radiology. Nephrol Dial Transplant 15: 2029-2036, 2000
11. Asif A, Gadalean FN, Merrill D, Cherla G, Cipleu CD, Epstein DL, Roth D: Inflow stenosis in arteriovenous fistulas and grafts: A multicenter, prospective study. Kidney Int 67: 1986-1992, 2005
12. Stracke S, Konner K, Kostlin I, Friedl R, Jehle PM, Hornbach V, Keller F, Waltenberger J: Increased expression of TGF-beta1 and IGF-I in inflammatory stenotic lesions of hemodialysis fistulas. Kidney Int 61: 1011-1019, 2002
13. Weiss MF, Scivittaro V, Anderson JM: Oxidative stress and increased expression of growth factors in lesions of failed hemodialysis access. Am J Kidney Dis 37: 970-980, 2001
14. Beathard GA: The treatment of vascular access dysfunction: A nephrologists view and experience. Adv Ren Replace Ther 1: 131-147, 1994
15. Roy-Chaudhury P, Kelly BS, Miller MA, Reaves A, Armstrong J, Nanayakkara N, Heffelfinger SC: Venous neointimal hyperplasia in polytetrafluoroethylene dialysis grafts. Kidney Int 59: 2325-2334, 2001
16. Rekhter MD, Gordon D: Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques. Am J Pathol 147: 668-677, 1995
17. Swedberg SH, Brown BG, Sigley R, Wight TN, Gordon D, Nicholls SC: Intimal fibromuscular hyperplasia at the venous anastomosis of PTFE grafts in hemodialysis patients. Clinical, immunocytochemical, light and electron microscopic assessment. Circulation 80: 1726-1736, 1989
18. Heine GH, Ulrich C, Kohler H, Girndt M: Is AV fistula patency associated with angiotensin-converting enzyme (ACE) polymorphism and ACE inhibitor intake? Am J Nephrol 24: 461-468, 2004
19. Allon M, Robbin ML: Increasing arteriovenous fistulas in hemodialysis patients: Problems and solutions. Kidney Int 62: 1109-1124, 2002
20. Remuzzi A, Ene-Iordache B, Mosconi L, Bruno S, Anghileri A, Antiga L, Remuzzi G: Radial artery wall shear stress evaluation in patients with arteriovenous fistula for hemodialysis access. Biorheology 40: 423-430, 2003
21. Paszkowiak JJ, Dardik A: Arterial wall shear stress: Observations from the bench to the bedside. Vasc Endovascular Surg 37: 47-57, 2003
22. Mezzano D, Pais EO, Aranda E, Panes O, Downey P, Ortiz M, Tagle R, Gonzalez F, Quiroga T, Caceres MS, Leighton F, Pereira J: Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia. Kidney Int 60: 1844-1850, 2001
23. Chang CJ, Ko PJ, Hsu LA, Ko YS, Ko YL, Chen CF, Huang CC, Hsu TS, Lee YS, Pang JH: Highly increased cell proliferation activity in the restenotic hemodialysis vascular access after percutaneous transluminal angioplasty: Implication in prevention of restenosis. Am J Kidney Dis 43: 74-84, 2004
24. Roy-Chaudhury P, Kelly BS, Zhang J, Narayana A, Desai P, Melham M, Duncan H, Heffelfinger SC: Hemodialysis vascular access dysfunction: From pathophysiology to novel therapies. Blood Purif 21: 99-110, 2003
25. Motwani JG, Topol EJ: Aortocoronary saphenous vein graft disease: Pathogenesis, predisposition, and prevention. Circulation 97: 916-931, 1998
26. Adams LD, Geary RL, McManus B, Schwartz SM: A comparison of aorta and vena cava medial message expression by cDNA array analysis identifies a set of 68 consistently differentially expressed genes, all in aortic media. Circ Res 87: 623-631, 2000
27. Albers FJ: Causes of hemodialysis access failure. Adv Ren Replace Ther 1: 107-118, 1994
28. Kim SJ, Masaki T, Leypoldt JK, Kamerath CD, Mohammad SF, Cheung AK: Arterial and venous smooth-muscle cells differ in their responses to antiproliferative drugs. J Lab Clin Med 144: 156-162, 2004
29. Kim SJ, Masaki T, Rowley R, Kamerath CD, Leypoldt JK, Mohammed SF, Cheung AK: Effect of radiation on arterial and venous smooth muscle cells in culture [Abstract]. J Am Soc Nephrol 12: 292A, 2001
30. Kelly BS, Heffelfinger SC, Whiting JF, Miller MA, Reaves A, Armstrong J, Narayana A, Roy-Chaudhury P: Aggressive venous neointimal hyperplasia in a pig model of arteriovenous graft stenosis. Kidney Int 62: 2272-2280, 2002
31. Kohler TR, Kirkman TR: Dialysis access failure: A sheep model of rapid stenosis. J Vasc Surg 30: 744-751, 1999
32. Masaki T, Rathi R, Zentner G, Leypoldt JK, Mohammad SF, Burns GL, Li L, Zhuplatov S, Chirananthavat T, Kim SJ, Kern S, Holman J, Kim SW, Cheung AK: Inhibition of neointimal hyperplasia in vascular grafts by sustained perivascular delivery of paclitaxel. Kidney Int 66: 2061-2069, 2004
33. Nugent HM, Groothuis A, Seifert P, Guerraro JL, Nedelman M, Mohanakumar T, Edelman ER: Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: A safety and efficacy study in the pig. J Vasc Res 39: 524-533, 2002
34. Libby P, Tanaka H: The molecular bases of restenosis. Prog Cardiovasc Dis 40: 97-106, 1997
35. O'Brien JE Jr, Shi Y, Fard A, Bauer T, Zalewski A, Mannion JD: Wound healing around and within saphenous vein bypass grafts. J Thorac Cardiovasc Surg 114: 38-45, 1997
36. Kwon HM, Sangiorgi G, Ritman EL, McKenna C, Holmes DR Jr, Schwartz RS, Lerman A: Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia. J Clin Invest 101: 1551-1556, 1998
37. Morice MC, Serruys PW, Sousa JE, Fajadet J, Ban Hayashi E, Perin M, Colombo A, Schuler G, Barragan P, Guagliumi G, Molnar F, Falotico R: A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med 346: 1773-1780, 2002
38. Stone GW, Ellis SG, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, Turco M, Caputo R, Bergin P, Greenberg J, Popma JJ, Russell ME: A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med 350: 221-231, 2004
39. Shi Y, O'Brien JE, Fard A, Mannion JD, Wang D, Zalewski A: Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 94: 1655-1664, 1996
40. Shi Y, O'Brien JE Jr, Mannion JD, Morrison RC, Chung W, Fard A, Zalewski A: Remodeling of autologous saphenous vein grafts. The role of perivascular myofibroblasts. Circulation 95: 2684-2693, 1997
41. Scott NA, Cipolla GD, Ross CE, Dunn B, Martin FH, Simonet L, Wilcox JN: Identification of a potential role for the adventitia in vascular lesion formation after balloon over-stretch injury of porcine coronary arteries. Circulation 93: 2178-2187, 1996
42. Roy-Chaudhury P, McKee L, Miller M, Reaves A, Armstrong J, Duncan H, Munda R, Kelly B, Heffelfinger S: Adventitial fibroblasts contribute to venous neointimal hyperplasia in PTFE dialysis grafts [Abstract]. J Am Soc Nephrol 12: 301A, 2001
43. Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, Hirai H, Makuuchi M, Hirata Y, Nagai R: Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 8: 403-409, 2002
44. Diao YGM, Guthrie S, Scott E, Segal MS: Role of circulating progenitor cells in the development of venous intimal hyperplasia [Abstract]. J Am Soc Nephrol 13: 58A-59A, 2002
45. Fukuda D, Sata M, Tanaka K, Nagai R: Potent inhibitory effect of sirolimus on circulating vascular progenitor cells. Circulation 111: 926-931, 2005
46. Urbich C, Dimmeler S: Endothelial progenitor cells: Characterization and role in vascular biology. Circ Res 95: 343-353, 2004
47. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM: Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967, 1997
48. Szmitko PE, Fedak PW, Weisel RD, Stewart DJ, Kutryk MJ, Verma S: Endothelial progenitor cells: New hope for a broken heart. Circulation 107: 3093-3100, 2003
49. Urao N, Azuma A: Erythropoietin prevents neointimal hyperplasia alter intimal injury by mobilizing endothelial precursor cells to accelerate endothelialization [Abstract 699]. Presented at the American Heart Association Annual Meeting, New Orleans, November 2004
50. Werner N, Junk S, Laufs U, Link A, Walenta K, Bohm M, Nickenig G: Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res 93: e17-e24, 2003
51. Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, Dzau VJ: Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: Implications for cell-based vascular therapy. Circulation 108: 2710-2715, 2003
52. Shears LL 2nd, Kibbe MR, Murdock AD, Billiar TR, Lizonova A, Kovesdi I, Watkins SC, Tzeng E: Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo. J Am Coll Surg 187: 295-306, 1998
53. Kipshidze N, Dangas G, Tsapenko M, Moses J, Leon MB, Kutryk M, Serruys P: Role of the endothelium in modulating neointimal formation: Vasculoprotective approaches to attenuate restenosis after percutaneous coronary interventions. J Am Coll Cardiol 44: 733-739, 2004
54. Garg UC, Hassid A: Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83: 1774-1777, 1998
55. Kong D, Melo LG, Gnecchi M, Zhang L, Mostoslavsky G, Liew CC, Pratt RE, Dzau VJ: Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. Circulation 110: 2039-2046, 2004
56. Corpataux JM, Haesler E, Silacci P, Ris HB, Hayoz D: Low-pressure environment and remodelling of the forearm vein in Brescia-Cimino haemodialysis access. Nephrol Dial Transplant 17: 1057-1062, 2002
57. Mattsson EJ, Kohler TR, Vergel SM, Clowes AW: Increased blood flow induces regression of intimal hyperplasia. Arterioscler Thromb Vasc Biol 17: 2245-2249, 1997
58. Nyberg SL, Hughes CB, Valenzuela YM, Jenson BM, Benda MM, McCarthy JT, Sterioff S, Stegall MD: Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access. ASAIO J 47: 333-337, 2001
59. Beathard GA, Arnold P, Jackson J, Litchfield T: Aggressive treatment of early fistula failure. Kidney Int 64: 1487-1494, 2003
60. Beathard GA, Settle SM, Shields MW: Salvage of the non-functioning arteriovenous fistula. Am J Kidney Dis 33: 910-916, 1999
61. Asif A, Cherla G, Merrill D, Cipleu CD, Briones P, Pennell P: Conversion of tunneled hemodialysis catheter-consigned patients to arteriovenous fistula. Kidney Int 67: 2399-2406, 2005
62. Faiyaz R, Abreo K, Zaman F, Pervez A, Zibari G, Work J: Salvage of poorly developed arteriovenous fistulae with percutaneous ligation of accessory veins. Am J Kidney Dis 39: 824-827, 2002
63. Diskin CJ, Stokes TJ Jr, Pennell AT: Pharmacologic intervention to prevent hemodialysis vascular access thrombosis. Nephron 64: 1-26, 1993
64. Sreedhara R, Himmelfarb J, Lazarus JM, Hakim RM: Anti-platelet therapy in graft thrombosis: Results of a prospective, randomized, double-blind study. Kidney Int 45: 1477-1483, 1995
65. Schmitz PG, McCloud LK, Reikes ST, Leonard CL, Gellens ME: Prophylaxis of hemodialysis graft thrombosis with fish oil: Double-blind, randomized, prospective trial. J Am Soc Nephrol 13: 184-190, 2002
66. Gradzki R, Dhingra RK, Port FK, Roys E, Weitzel WF, Messana JM: Use of ACE inhibitors is associated with prolonged survival of arteriovenous grafts. Am J Kidney Dis 38: 1240-1244, 2001
67. Gallo R, Padurean A, Jayaraman T, Marx S, Roque M, Adelman S, Chesebro J, Fallon J, Fuster V, Marks A, Badimon JJ: Inhibition of intimal thickening after balloon angioplasty in porcine coronary arteries by targeting regulators of the cell cycle. Circulation 99: 2164-2170, 1999
68. Murthy SN, Obregon DF, Chattergoon NN, Fonseca NA, Mondal D, Dunne JB, Diez JG, Jeter JR Jr, Kadowitz PJ, McNamara DB, Fonseca VA: Rosiglitazone reduces serum homocysteine levels, smooth muscle proliferation, and intimal hyperplasia in Sprague-Dawley rats fed a high methionine diet. Metabolism 54: 645-652, 2005
69. Wang CH, Ciliberti N, Li SH, Szmitko PE, Weisel RD, Fedak PW, Al-Omran M, Cherng WJ, Li RK, Stanford WL, Verma S: Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: A new paradigm in glitazone pleiotropy. Circulation 109: 1392-1400, 2004
70. Hausleiter J, Kastrati A, Mehilli J, Vogeser M, Zohlnhofer D, Schuhlen H, Fache J, Dotzer F, Pogatsa-Murray GJ, Heemann U, Schomig A: Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: The Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial. Circulation 110: 790-795, 2004
71. Takagi T, Yamamuro A, Tamita K, Katayama M, Morioka S: Thiazolidinedione treatment attenuates diffuse neointimal hyperplasia in restenotic lesions after coronary stent implantation in type 2 diabetic patients: An intravascular ultrasound study. J Cardiol 45: 139-147, 2005
72. Fareh J, Martel R, Kermani P, Leclerc G: Cellular effects of beta-particle delivery on vascular smooth muscle cells and endothelial cells: A dose-response study. Circulation 99: 1477-1484, 1999
73. Haimovitz-Friedman A, Fuks Z: Signaling in the radiation response of endothelial cells. In: The Radiation Biology of the Vascular Endothelium, edited by Rubin DB, Boston, CRC Press, 1999, pp 101-127
74. Rubin P, Williams JP, Riggs PN, Bartos S, Sarac T, Pomerantz R, Castano J, Schell M, Green RM: Cellular and molecular mechanisms of radiation inhibition of restenosis. Part I: Role of the macrophage and platelet-derived growth factor. Int J Radiat Oncol Biol Phys 40: 929-941, 1998
75. Sabate M, Serruys PW, van der Giessen WJ, Ligthart JM, Coen VL, Kay IP, Gijzel AL, Wardeh AJ, den Boer A, Levendag PC: Geometric vascular remodeling after balloon angioplasty and beta-radiation therapy: A three-dimensional intravascular ultrasound study. Circulation 100: 1182-1188, 1999
76. Mayberg MR, Luo Z, London S, Gajdusek C, Rasey JS: Radiation inhibition of intimal hyperplasia after arterial injury. Radiat Res 142: 212-220, 1995
77. Waksman R, Robinson KA, Crocker IR, Gravanis MB, Cipolla GD, King SB 3rd: Endovascular low-dose irradiation inhibits neointima formation after coronary artery balloon injury in swine. A possible role for radiation therapy in restenosis prevention. Circulation 91: 1533-1539, 1995
78. Leon MB, Teirstein PS, Moses JW, Tripuraneni P, Lansky AJ, Jani S, Wong SC, Fish D, Ellis S, Holmes DR, Kuntz RE: Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. N Engl J Med 344: 250-256, 2001
79. Raizner AE, Oesterle SN, Waksman R, Serruys PW, Colombo A, Lim YL, Yeung AC, van der Giessen WJ, Vandertie L, Chiu JK, Fitzgerald PJ, Kaluza GL, Ali NM: Inhibition of restenosis with beta-emitting radiotherapy: Report of the Proliferation Reduction with Vascular Energy Trial (PREVENT). Circulation 102: 951-958, 2000
80. Kelly BS, Narayana A, Heffelfinger SC, Roy-Chaudhury P: External beam radiation attenuates venous neointimal hyperplasia in a pig model of arteriovenous polytetrafluoroethylene (PTFE) graft stenosis. Int J Radiat Oncol Biol Phys 54: 263-269, 2002
81. Sun S, Beitler JJ, Ohki T, Calderon TM, Scheduler R, Yaparpalvi R, Berman JW, Tellis VA, Greenstein SM: Inhibitory effect of brachytherapy on intimal hyperplasia in arteriovenous fistula. J Surg Res 115: 200-208, 2003
82. Rodriguez VM, Grove J, Yelich S, Pearson D, Stein M, Pevec WC: Effects of brachytherapy on intimal hyperplasia in arteriovenous fistulas in a porcine model. J Vasc Interv Radiol 13: 1239-1246, 2002
83. Roy-Chaudhury P, Mishra S: BRAVO I: A pilot study of endovascular radiation therapy for PTFE dialysis grafts [Abstract]. J Am Soc Nephrol 14: 508A, 2003
84. Roy-Chaudhury P, Zuckerman D, Duncan H, Foley J, Misra S: Endovascular radiation therapy reduces venous stenosis in PTFE dialysis access grafts [Abstract]. J Am Soc Nephrol 15: 61A, 2004
85. Sukhatme: Vascular access stenosis: Prospects for prevention and therapy. Kidney Int 49: 1161-1174, 1996
86. Qian HS, Channon K, Neplioueva V, Wang Q, Finer M, Tsui L, George SE, McArthur J: Improved adenoviral vector for vascular gene therapy. Beneficial effects on vascular function and inflammation. Circ Res 88: 911-917, 2001
87. Corgentech and Bristol-Myers Squibb Announce Results from Edifoligide (E2F Decoy) Phase 3 Trial for Coronary Artery Bypass Graft Failure, 2005. Available: www.bms. com/news/press/data/pf_press_release_5492.html. Accessed June 8, 2005
88. Corgentech and Bristol-Myers Squibb Announce Results from Edifoligide (E2F Decoy) Phase 3 Trial For Peripheral Bypass Graft, 2004. Available: www.shareholder.com/cgtk/ReleaseDetail.cfm?ReleaseID=149870. Accessed February 14, 2006
89. Suzuki T, Kopia G, Hayashi S, Bailey LR, Llanos G, Wilensky R, Klugherz BD, Papandreou G, Narayan P, Leon MB, Yeung AC, Tio F, Tsao PS, Falotico R, Carter AJ: Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation 104: 1188-1193, 2001
90. Heldman AW, Cheng L, Jenkins GM, Heller PF, Kim DW, Ware M Jr, Nater C, Hruban RH, Rezai B, Abella BS, Bunge KE, Sollott SJ, Lakatta EG, Brinker JA, Hunter WL, Froehlich JP: Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis. Circulation 103: 2289-2295, 2001
91. Sousa JE, Costa MA, Abizaid A, Feres F, Seixas AC, Tanajura LF, Mattos LA, Falotico R, Jaeger J, Popma JJ, Serruys PW, Sousa AG: Four-year angiographic and intravascular ultrasound follow-up of patients treated with sirolimus-eluting stents. Circulation 111: 2326-2329, 2005
92. Cypher Stent Edges Out Taxus in Three Studies, 2005. www.medscape.com/ viewarticle/501041. Accessed June 8, 2005
93. Hoffer EK, Sultan S, Herskowitz MM, Daniels ID, Sclafani SJ: Prospective randomized trial of a metallic intravascular stent in hemodialysis graft maintenance. J Vasc Interv Radiol 8: 965-973, 1997
94. Beathard GA: Gianturco self-expanding stent in the treatment of stenosis in dialysis access grafts. Kidney Int 43: 872-877, 1993
95. Rotmans JI, Pattynama PM, Verhagen HJ, Hino I, Velema E, Pasterkamp G, Stroes ES: Sirolimus-eluting stents to abolish intimal hyperplasia and improve flow in porcine arteriovenous grafts: A 4-week follow-up study. Circulation 111: 1537-1542, 2005
96. Kaufman JS, O'Connor TZ, Zhang JH, Cronin RE, Fiore LD, Ganz MB, Goldfarb DS, Peduzzi PN: Randomized controlled trial of clopidogrel plus aspirin to prevent hemodialysis access graft thrombosis. J Am Soc Nephrol 14: 2313-2321, 2003
97. Goteti KTM, Kuji T, Leypoldt J, Mohammad S, Cheung A, Kern S: Pharmacokinetics of local dipyridamole transport for prevention of hemodialysis vascular access stenosis [Abstract]. J Am Soc Nephrol 15: 152A, 2004
98. Goteti KTM, Kuji T, Leypoldt J, Mohammad S, Cheung A, Kern S: In vivo pharmacokinetics of local dipyridamole transport for prevention of hemodialysis vascular access stenosis [Abstract]. J Am Soc Nephrol 16: 10A, 2005
99. Kelly B, Melhem M, Desai P, Kasting G, Zhang J, Li J, Heffelfinger S, Rudich S, Roy-Chaudhury P: Perivascular paclitaxel polymers reduce neointimal hyperplasia and venous stenosis in PTFE arteriovenous grafts: A possible solution for hemodialysis vascular access dysfunction [Abstract]. J Am Soc Nephrol 15: 25A, 2004
100. Zhu W, Masaki T, Bae YH, Rathi R, Cheung AK, Kerns SE: Development of a sustained-release system for perivascular delivery of dipyridamole. J Biomed Mater Res B Appl Biomater October 3, 2005 [Epub ahead of print]
101. Frost MC, Reynolds MM, Meyerhoff ME: Polymers incorporating nitric oxide releasing/generating substances for improved biocompatibility of blood-contacting medical devices. Biomaterials 26: 1685-1693, 2005
102. Fleser PS, Nuthakki VK, Malinzak LE, Callahan RE, Seymour ML, Reynolds MM, Merz SI, Meyerhoff ME, Bendick PJ, Shanley CJ: Nitric oxide-releasing biopolymers inhibit thrombus formation in a sheep model of arteriovenous bridge grafts. J Vasc Surg 40: 803-811, 2004
103. Dardik A, Liu A, Ballermann BJ: Chronic in vitro shear stress stimulates endothelial cell retention on prosthetic vascular grafts and reduces subsequent in vivo neointimal thickness. J Vasc Surg 29: 157-167, 1999
104. Bowlin GL, Rittgers SE: Electrostatic endothelial cell transplantation within small-diameter (<6 mm) vascular prostheses: A prototype apparatus and procedure. Cell Transplant 6: 631-637, 1997
105. Shirota T, Yasui H, Shimokawa H, Matsuda T: Fabrication of endothelial progenitor cell (EPC)-seeded intravascular stent devices and in vitro endothelialization on hybrid vascular tissue. Biomaterials 24: 2295-2302, 2003
106. Bhattacharya V, McSweeney PA, Shi Q, Bruno B, Ishida A, Nash R, Storb RF, Sauvage LR, Hammond WP, Wu MH: Enhanced endothelialization and microvessel formation in polyester grafts seeded with CD34(+) bone marrow cells. Blood 95: 581-585, 2000
107. Ong AT, Aoki J, Kutryk MJ, Serruys PW: How to accelerate the endothelialization of stents. Arch Mal Coeur Vaiss 98: 123-126, 2003
108. Aoki J, Serruys PW, van Beusekom H, Ong AT, McFadden EP, Sianos G, van der Giessen WJ, Regar E, de Feyter PJ, Davis HR, Rowland S, Kutryk MJ: Endothelial progenitor cell capture by stents coated with antibody against CD34: The HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth-First In Man) Registry. J Am Coll Cardiol 45: 1574-1579, 2005
109. Rotmans JI, Heyligers JMM, Verhagen HJM, Velema E, Nagtegaal MM, de Kleijn DPV, de Groot FG, Stroes ESG, Pasterkamp G: In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts. Circulation 112: 12-18, 2005
110. Deb A, Skelding KA, Wang S, Reeder M, Simper D, Caplice NM: Integrin profile and in vivo homing of human smooth muscle progenitor cells. Circulation 110: 2673-2677, 2004
111. Nugent HM, Rogers C, Edelman ER: Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. Circ Res 84: 384-391, 1999
112. Malovrh M: Native arteriovenous fistula: Preoperative evaluation. Am J Kidney Dis 39: 1218-1225, 2002
113. Malovrh M: Non-invasive evaluation of vessels by duplex sonography prior to construction of arteriovenous fistulas for haemodialysis. Nephrol Dial Transplant 13: 125-129, 1998
114. Malovrh M: The role of sonography in the planning of arteriovenous fistulas for hemodialysis. Semin Dial 16: 299-303, 2003
115. Chou TM, Woodburn KW, Cheong WF, Lacy SA, Sudhir K, Adelman DC, Wahr D: Photodynamic therapy: Applications in atherosclerotic vascular disease with motexafin lutetium. Catheter Cardiovasc Interv 57: 387-394, 2002
116. Jenkins MP, Buonaccorsi GA, Mansfield R, Bishop CC, Bown SG, McEwan JR: Reduction in the response to coronary and iliac artery injury with photodynamic therapy using 5-aminolaevulinic acid. Cardiovasc Res 45: 478-485, 2000
117. Burgher JM, Barton JM, Farooq MM, Vasek J, Scott RW, Freischlag JA, Grove RI: PhotoPoint photodynamic therapy with local drug delivery eliminates vessel wall cells in arteriovenous graft models. Cardiovasc Radiat Med 3: 163-168, 2002
118. Fava M, Loyola S, Polydorou A, Papapavlou P, Mendiz O, Joye JD: Cryoplasty for femoropopliteal arterial disease: Late angiographic results of initial human experience. J Vasc Interv Radiol 15: 1239-1243, 2004
119. Rifkin BS, Brewster UC, Aruny JE, Perazella MA: Percutaneous balloon cryoplasty: A new therapy for rapidly recurrent anastomotic venous stenoses of hemodialysis grafts? Am J Kidney Dis 45: e27-e32, 2005
120. Stent graft outperforms balloon angioplasty, 2005. Available: http://www.news-medical.net/?id=8920. Accessed June 8, 2005
121. Sidawy AN, Gray R, Besarab A, Henry M, Ascher E, Silva M Jr, Miller A, Scher L, Trerotola S, Gregory RT, Kent KC: Recommended standards for reports dealing with arteriovenous hemodialysis accesses. J Vasc Surg 35: 603-610, 2002
122. Gray RJ, Sacks D, Martin LG, Trerotola SO: Reporting standards for percutaneous interventions in dialysis access. J Vasc Interv Radiol 14: S433-S442, 2003