A modeling study of bilirubin kinetics during molecular adsorbent recirculating system sessions

Artificial Organs

Volumn 30, Issue 4, 2006, Pages 285-300

  Magosso, Elisa ^a,b   Ursino, Mauro ^a   Colì, Luigi ^a   Baraldi, Olga ^a   Bolondi, Luigi ^a   Stefoni, Sergio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Informatica e Sistemistica   (Italy)

Author keywords

Albumin dialysis; Albumin bilirubin binding kinetics; Compartment; Mathematical modeling; Molecular Adsorbent Recirculating System; Parameter estimation

Indexed keywords

BLOOD; KINETICS;

ALBUMIN DIALYSIS; ALBUMIN-BILIRUBIN BINDING KINETIC; BILIRUBIN REMOVAL; BINDING KINETICS; COMPARTMENT; MATHEMATICAL MODELING; MOLECULAR ADSORBENT RECIRCULATING SYSTEM; PARAMETERS ESTIMATION; RECIRCULATING SYSTEM; THREE PARAMETERS;

PARAMETER ESTIMATION;

ALBUMIN; BILIRUBIN;

ALBUMIN DIALYSIS; ARTICLE; BILIRUBIN METABOLISM; BINDING KINETICS; BLOOD FILTER; DETERIORATION; EXPERIMENTAL MODEL; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION;

EID: 33645463887     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2006.00216.x     Document Type: Article

References (23)

1. Daas M Plevak DJ Wijdicks EF et al. Acute liver failure: results of a 5 years clinical protocol Liver Transpl Surg 1995 1 210 9
2. Shakil AO Kramer D Mazariegos GV Fung JJ Rakela J Acute liver failure: clinical features, outcome analysis, and applicability of prognostic criteria Liver Transpl 2000 6 163 9
3. Ellis A Wendon J Circulatory, respiratory, cerebral, and renal derangements in acute liver failure: pathophysiology and management Semin Liver Dis 1996 16 379 88
4. Albrecht J Jones EA Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome J Neurol Sci 1999 170 138 46
5. Kaptanoglu L Blei AT Current status of liver support systems Clin Liver Dis 2000 4 711 29
6. Kjaergard LL Liu J Als-Nielsen B Gluud C Artificial and bioartificial support systems for acute and acute-on-chronic liver failure: a systematic review JAMA 2003 289 217 22
7. Malchesky PS Nonbiological liver support: historic overview Artif Organs 1994 18 342 7
8. Novelli G Rossi M Pretagostini R et al. MARS (molecular adsorbent recirculating system): experience in 34 cases of acute liver failure Liver 2002 22 Suppl. 2 43 7
9. Sen S Williams R Jalan R Emerging indications for albumin dialysis Am J Gastroenterol 2005 100 468 75
10. Stange J Ramlow W Mitzner S Schmidt R Klinkmann H Dialysis against a recycled albumin solution enables the removal of albumin-bound toxins Artif Organs 1993 17 809 13
11. Stange J Mitzner S Ramlow W Gliesche T Hickstein H Schmidt R A new procedure for the removal of protein-bound drugs and toxins ASAIO J 1993 39 621 5
12. Evenepoel P Maes B Wilmer A et al. Detoxifying capacity and kinetics of the molecular adsorbent recycling system Blood Purif 2003 21 244 52
13. Jalan R Sen S Steiner C Kapoor D Alisa A Williams R Extracorporeal liver support with molecular adsorbent recirculating system in patients with severe acute alcoholic hepatitis J Hepatol 2003 38 24 31
14. Klammt S Stange J Mitzner SR Peszynski P Peters E Liebe S Extracorporeal liver support by recirculating albumin dialysis: analysing the effect of the first clinically used generation of the MARSystem Liver 2002 22 Suppl. 2 30 4
15. Mitzner SR Stange J Klammt S Peszynski P Schmidt R Nöldge-Schomburg G Extracorporeal detoxification using the molecular adsorbent recirculating system for critically ill patients with liver failure J Am Soc Nephrol 2001 12 S75 S82
16. Guyton AC Textbook of Medical Physiology Philadelphia, PA WB Saunders 1986
17. Sargent JA Gotch FA Principles and biophysics of dialysis In Drukker W Parson FM Mather JF eds Replacement of Renal Function by Dialysis Boston, MA Kluwer Academic Press 1989 85 139
18. Berk PD Howe RB Bloomer JR Berlin NI Studies of bilirubin kinetics in normal adults J Clin Invest 1969 48 2176 90
19. Gray RD Stroupe SD Kinetics and mechanism of bilirubin binding to human serum albumin J Biol Chem 1978 253 4370 7
20. Berde CB Hudson BS Simoni RD Sklar LA Human serum albumin J Biol Chem 1979 254 391 400
21. Breaven GH D'Albis A Gratzer WB The interaction of bilirubin with human serum albumin Eur J Biochem 1973 33 500 9
22. Jacobsen J Binding of bilirubin to human serum albumin. Determination of the dissociation constants FEBS Lett 1969 5 112 4
23. Weisiger RA Ostrow JD Koehler RK et al. Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: results of a novel ultrafiltration method J Biol Chem 2001 276 29953 60