Sildenafil citrate (revatio) for the treatment of pulmonary arterial hypertension

P and T

Volumn 31, Issue 3, 2006, Pages 135-138

  Bell, Amber ^a   Davis, Myesha ^a   Close, Fran ^b   Honeywell, Marlon ^c   Branch III, Evans ^d  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b Institute of Public Health   (United States)

^c Department of Pharmacy Practice   (United States)

^d University's College of Pharmacy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN; CIMETIDINE; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DOXAZOSIN; ERYTHROMYCIN; ILOPROST; ITRACONAZOLE; KETOCONAZOLE; NITRIC OXIDE; PLACEBO; PROSTACYCLIN; RITONAVIR; SAQUINAVIR; SILDENAFIL; VITAMIN K GROUP;

AREA UNDER THE CURVE; ARTERIAL OXYGEN SATURATION; DIARRHEA; DIZZINESS; DRUG ABSORPTION; DRUG APPROVAL; DRUG BIOAVAILABILITY; DRUG CONTRAINDICATION; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DYSPEPSIA; DYSPNEA; EPISTAXIS; ERECTILE DYSFUNCTION; FLUSHING; FOLLOW UP; FOOD AND DRUG ADMINISTRATION; FUNCTIONAL ASSESSMENT; GERIATRIC PATIENT; HEADACHE; HEART INDEX; HEART OUTPUT; HEART PERFORMANCE; HEART RATE; HEART RIGHT ATRIUM PRESSURE; HUMAN; INSOMNIA; INTENSIVE CARE UNIT; KIDNEY FAILURE; LIVER FAILURE; LUNG ARTERY PRESSURE; LUNG CAPILLARY PRESSURE; MEAN ARTERIAL PRESSURE; MONOTHERAPY; MYALGIA; PULMONARY HYPERTENSION; RETINA HEMORRHAGE; REVIEW; STEADY STATE; SYSTEMATIC REVIEW; VASCULAR RESISTANCE; VOLUNTEER; WALKING;

EID: 33645451509     PISSN: 10521372     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. Recommendations on the management of pulmonary hypertension in clinical practice. Heart 2001;86(Suppl 1):i1-i13.
2. Simonneau G, Galie N, Rubin L, et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004;43(12 Suppl S):5S-12S.
3. Newman J, Fanburg B, Archer S, et al. Pulmonary Arterial Hypertension: Future Directions. Report of a National Heart, Lung and Blood Institute/Office of Rare Diseases Workshop. Circulation 2004;109:2947-2952.
4. Cohen H, Chahine C, Hui A, et al. Bosentan therapy for pulmonary arterial hypertension. Am J Health Syst Pharm 2004;61:1107-1119.
5. Rubin LJ. Primary pulmonary hypertension. N Engl J Med 1997;336:111-117.
6. Revatio (sildenafil citrate) [prescribing information]. New York: Pfizer Inc.; June 2005.
7. Bhatia S, Frantz R, Severson C, et al. Immediate and long-term hemodynamic and clinical effects of sildenafil in patients with pulmonary arterial hypertension receiving vasodilator therapy. Mayo Clin Proc 2003;78:1207-1213.
8. Ghofrani H, Wiedemann R, Rose F, et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002;136:515-522.
9. Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004;351:1425-1436.
10. MedPage Today. Revatio, a Viagra spin-off, okayed for pulmonary arterial hypertension. June 7, 2005. Available at: www. medpagetoday.com. Accessed February 15, 2006.