Targeting rickettsia

New England Journal of Medicine

Volumn 354, Issue 13, 2006, Pages 1418-1420

  Walker, David H ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CHLORAMPHENICOL; DOXYCYCLINE; MACROLIDE; TETRACYCLINE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ARTICLE; CLINICAL FEATURE; ENDOCYTOSIS; HUMAN; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RICKETTSIA; RICKETTSIA CONORII; RICKETTSIOSIS; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; ANTIGENS, NUCLEAR; CELLS, CULTURED; DNA-BINDING PROTEINS; DRUG RESISTANCE, BACTERIAL; ENDOCYTOSIS; HUMANS; PROTEIN BINDING; RICKETTSIA CONORII; RICKETTSIA INFECTIONS; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 33645414335     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr055756     Document Type: Article

References (5)

1. Martinez JJ, Seveau S, Veiga E, Matsuyama S, Cossart P. Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii. Cell 2005;123:1013-23.
2. Martinez JJ, Cossart P. Early signaling events involved in the entry of Rickettsia conorii into mammalian cells. J Cell Sci 2004;117:5097-106.
3. Whitworth T, Popov VL, Yu XJ, Walker DH, Bouyer DH. Expression of the Rickettsia prowazekii pld or tlyC gene in Salmonella enterica serovar Typhimurium mediates phagosomal escape. Infect Immun 2005;73:6668-73.
4. Gouin E, Egile C, Dehoux P, et al. The RickA protein of Rickettsia conorii activates the Arp2/3 complex. Nature 2004;427:457-61.
5. Feng H-M, Whitworth T, Olano JP, Popov VL, Walker DH. Fc-dependent polyclonal antibodies and antibodies to outer membrane proteins A and B, but not to lipopolysaccharide, protect SCID mice against fatal Rickettsia conorii infection. Infect Immun 2004;72:2222-8.