Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential for their practical application

Biology Bulletin

Volumn 33, Issue 2, 2006, Pages 153-161

  Lyapina, L A ^a   Pastorova, V E ^a   Obergan, T Yu ^a   Samonina, G E ^a   Ashmarin, I P ^a   Myasoedov, N F ^b  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 33645405352     PISSN: 10623590     EISSN: None     Source Type: Journal    
DOI: 10.1134/S1062359006020099     Document Type: Article

References (50)

1. 3 Inhibitor Preserves Microvascular Patency in Experimental Acute Focal Cerebral Ischemia, Stroke, 2000, vol. 31, pp. 1402-1410.
2. Ahmed, A.K., Warnock, M., Nieman, M., Srikanth, S., Mahdi, F., Krishnan, R., Tuhnsky, A., and Schmaier, A.H., Mechanisms of Arg-Pro-Gly-Phe Inhibition of Thrombin, J. Physiol Heart Circ Physiol, 2003, vol. 285, pp. 183-193.
3. Ashmarin, I.P., Pastorova, V.E., Lyapina, L.A., Kudryashov, B.A., Kalikhevich, V.A., Kamenskii, A.A., and Azieva, L.D., The effect of Tuftsin on Fibrin Polymerization in Vitro and on the Hemostatic System When Administered Intravenously to Healthy Animals, Izv. Akad. Nauk SSSR. Ser. Biol., 1991, no. 2, pp. 302-308.
4. Ashmarin, I.P., Lyapina, L.A., and Pastorova, V.E., Modulation of Hemostatic Reactions in vitro and in vivo by Representatives of Control Peptide Families, Vestn. Ross. Akad. Med. Nauk, 1996, no. 6, pp. 50-58.
5. Ashmarin, I.P., Levitskaya, N.G., Kamenskii, A.A., and Myasoedov, N.F., Semax - A New Drug for Correcting Cerebral Circulation, Hypoxic States, and Increasing Mental Activity, Farmateka, 1997, no. 4, pp. 32-33.
6. Ashmarin, I.P., Karazeeva, E.P., Lyapina, L.A., and Samonina, G.E., The Simplest Proline-Containing Peptides PG, GP, PGP and GPGG: Regulatory Activity and Possible Sources of Biosynthesis, Biokhimiya, 1998a, vol. 63, no. 2, pp. 134-141.
7. Ashmarin, I.P., Pastorova, V.E., and Lyapina, L.A., Effect of Simple Praline-Containing Peptides on the Functional Activity of the Anticoagulant System and Primary Homeostasis, Byull. Eksp. Biol. Med., 1998b, no. 5, pp. 496-499.
8. Ashmarin, I.P., Kamenskii, A.V., Lyapina, L.A., Myasoedov, N.F., and Samonina, G.E., Glyprolines as Independent Regulators and Stabilizers of Other Peptides, Vopr. Biol. Med. Farmatsevtich. Khim., 2002, no. 1, pp. 24-27.
9. Ashmarin, I.P., Samonina, G.E., Lyapina, L.A., Kamenskiy, A.A., Levitskaya, G.N., Grivennikov, VA., Dolotov, O.V., Andreeva, L.A., and Myasoedov, N.F., Natural and Hybrid ("Chimeric") Stable Regulatory Glyproline Peptides, Pathophysiol, 2005, vol. 11, pp. 179-185.
10. Bajusz, S., Barabas, E., Fauszt, J., et al., Active Site-Directed Thrombin Inhibitiors: Alpha-Hydroxydeyl-Prolyl-Arginin. New Orally Active Stable Analogs of D-Phe-Pro-Arg-H, Bioorg. Med. Chem., 1995, vol. 3, no. 8, pp. 1079-1089.
11. Barker, P.L., Bullens, S., and Bunting, S., Cyclic RGD Peptide Analogues as Antiplatelets Antithrombotics, J. Med. Chem., 1992, vol. 35, pp. 2040-2048.
12. Barnes, M.J., Knight, C.G., and Farndale, R.W., The Use of Collagen-Based Model Peptides to Investigate Platelet-Reactive Sequences in Collagen, Biopolymers, 1996, vol. 40, pp. 383-397.
13. Bienkowsk, M., Cowan, J., and McDonald, R.C., Degradation of Newly Synthesized Collagen, J. Biol. Chem., 1978, vol. 253, pp. 4356-4363.
14. Bokarev, I.N., Laboratory Methods to Study Blood Coagulation in Clinical Practice, in Tromby, krovotochivost' i bolezni sosudov. Prilozhenie no. 2 (Clots and Vascular Hemorrhagic Diathesis and Other Diseases), Moscow: MMA I.M. Sechenova, 2003, pp. 5-9.
15. Byshevskii A.Sh., Chiryat'ev E.A., Umutbaeva M.K., Tazhudinova S.I., Regulator Peptide of Blood Aggregation Function at the Stage of Fibrin Self-Assembly, Gematol. Transfuziol., 1986, vol. 31, no. 6, pp. 26-31.
16. Cherkasova, L.A., Lyapina, L.A., and Ashmarin, I.P., Comparative Study of Semax and Simple Praline-Containing Peptides in Modulating Hemostatic Reactions, Byull. Eksp. Biol. Med., 2001, vol. 132, no. 7, pp. 20-22.
17. Chernukh, A.M., Gomazkov, O.A., Entsik, L.A., and Krizhevskaya, Yu.V., Bradykinin, Thrombin and Prostaglandins as Modulators of Microthrombogenesis in Local Injury of the Blood Vessel Wall, Byull. Eksp. Biol. Med., 1983, no. 1, pp. 30-32.
18. Chipens, G.I. and Veretennikova, N.I., Struktura i funktsii nizkomolekulyarnykh peptidov (Structure and Functions of Low Molecular Weight Peptides), Riga: Med. in-t, 1980.
19. Dolgov, V.V., Avdeeva, N.A., and Shchetnikovich, K.A., Metody issledovaniya gemostaza (Methods for Studying Hemostasis), Moscow: Izd-vo min-va zdravookhraneniya i medpromyshlennosti RF, 1996.
20. Doolittle, R.F., Spraggon, G., and Everse, S.J., Crystal Structures of Fragments D and Doble-D Form Fibrinogen and Fibrin, Thromb. Haemost., 1999, vol. 82, no. 2, pp. 271-276.
21. Farndale, R.W., Sixma, J.J., Barens, M.J., and de Groot, P.G., The Role of Collagen in Thrombosis and Haemostasis, J. Thromb. Haemost., 2004, vol. 2, no. 4, pp. 561-573.
22. Ganguly, K., Krasik, T., Medinilla, S., Bdeir, K., Cines, D.B., Muzykantov, V.R., and Murciano, J.C., Blood Clearance and Activity of Erythrocyte-Coupled Fibrinolytics, J. Pharmacol. Exp. Ther., 2005, vol. 312, pp. 1106-1113.
23. Gomazkov, O.A., Peptidy v kardiologii: Biokhimiya, fiziologiya, patologiya, informatsiya, analiz (Peptides in Cardiology: Biochemistry, Physiology, Pathology, Information, Analysis), Moscow: Materik al'fa, 2000.
24. Gouwy, M., Struyf, S., Catusse, J., Proost, P., and Damme, J.V., Synergy between Proinflammatory Ligandes of G Protein-Coupled Receptors in Neutrophil Activation and Migration, J. Leukocyte Biol., 2004, vol. 76, pp. 185-194.
25. Hemker, H.C., Dieri, R.A., and Beguin, S., Laboratiry Monitoring of Low-Molecular-Weight Heparin Therapy. Part II, J. Thromb. Haemost., 2005, vol. 3, no. 3, pp. 371-376.
26. Karniguian, A., Legrand, Y.J., Lefrancier, P., and Caen, J.P., Effect of a Collagen-Derived Octapeptide on Different Steps of the Platelet/Collagen Interaction, Thromb. Res., 1983, vol. 32, pp. 593-604.
27. Kini, R. and Evans, H.A., Novel Approach to the Design of Potent Bioactive Peptides by Incorporation of Proline Brackets: Antiplatelet Effects of Arg-Gly-Asp Peptides, FEBS Lett., 1995, vol. 375, no. 1, pp. 15-17.
28. Kirichuk, V.F. and Burova, M.B., Effect of Oxytocin on Fibrinolysis and the Status of the Kallikrein-Kinin System, Probl. Endokrinol., 1989, vol. 35, no. 2, pp. 81-84.
29. Laudano, A.P. and Doolittle, R.F., Studies on Synthetic Peptides That Bind to Fibrinogen and Prevent Fibrin Polimerisation. Structural Reguirements, Number of Binding Sites, and Species Differences, Biochemistry, 1980, vol. 19, pp. 1013-1019.
30. Levitskaya, N.G., Kleimenov, A.N., Petrosyan, M.T., Rozenfel'd, M.A., Kalikhevich, V.N., and Ardemasova, Z.A., Effect of Low-Molecular Peptides on the Fibrin-Fibrinogen Transformation, Byull. Eksp. Biol. Med., 1987, no. 7, pp. 190-192.
31. Lugovskoi, E.V., Molekulyarnye mekhanizmy obrazovaniya fibrina i fibrinoliza (Molecular Mechanisms of Fibrin Formation and Fibrinolysis), Kiev: Naukova Dumka, 2003.
32. Lyapina, L.A., Pastorova, V.E., Kudryashov, B.A., Zazhirei, V.D., Sokolova, E.A., Livshits, V.A., and Ashmarin, I.P., The Action of Thymoptin Peptides on the Hemostatic System, Izv. Akad. Nauk SSSR. Ser. Biol., 1990, no. 3, pp. 377-382.
33. Lyapina, L.A., Pastorova, V.E., Kondashevskaya, M.V., Kudryashov, B.A., and Kalikhevich, V.N., The Antithrombotic and Thrombolytic Activity of Tuftsin, Byull. Eksp. Biol. Med., 1994, vol. 118, no. 11, pp. 1317-1319.
34. Lyapina, L.A., Pastorova, V.E., Samonina, G.E., and Ashmarin, I.P., The Effect of Peptide PGP and PGP-Rich Preparation on Haemostatic Indexes of Rat Blood, Blood Coagulation Fibrinol., 2000, vol. 11, no. 1, pp. 1-6.
35. Lyapina, L.A., Pastorova, V.E., Ul'yanov, A.M., Tarasov, Yu.A., and Ashmarin, I.P., Effect of Gelatin and ProGlu-Pro Peptide on the Anticoagulation System Status and Development of Experimental Diabetes Mellitus, Vestn. Mosk. Univ., Ser. 16, 2002, no. 1, pp. 8-10.
36. Lyapina, L.A., Pastorova, V.E., and Smolina, T.Yu., The Role of Heparin Complexes with Collagen and Its HeparinBinding Fragments in the Activation of the Anticoagulant System, Tromboz, Gemostaz I Reologiya, 2003, vol. 2, no. 14, pp 57-61.
37. Meschengieser, S.S., Fondevila, C.G., Frontroth, J., Santarelli, M.T., and Lazzari, M.A., Low-Intensity Oral Anticoagulation plus Low-Dose Aspirin Versus High-Intensity Oral Anticoagulation Alone: A Randomized Trial in Patients with Mechanical Prosthetic Heart Valves, J. Thorac. Cardiovasc. Surg., 1997, vol. 113, pp. 910-916.
38. Monnet, E. and Fauvel-Lafeve, F., A New Platelet Receptor Specific to Type III Collagen.Type III Collagen-Binding Protein, J. Biol. Chem., 2000, vol. 275, pp. 10912-10907.
39. Ol'binskaya, L.I. and Gofman, A.M., Lechenie iprofilaktika trombozov (Treatment and Prevention of Trombosis), Moscow: VAGRIUS, 2000.
40. Pastorova, V.E., Lyapina, L.A., Smolina, T.Yu, and Ashmarin, I.P., Anticoagulant and Fibrinolytic Effects of Proline-Containing Peptides, Izv. Ross. Akad. Nauk. Ser. Biol., 1998, no. 3, pp. 390-394.
41. Pastorova, V.E., Lyapina, L.A., Ostrovskaya, R.U., Lugovskoi, E.V., Ashmarin, I.P., and Gudasheva, T.A., Fibrin-Depolymerization Activity and the Antiplatelet Effect of Small Cyclic and Linear Proline-Containing Peptides, Izv. Akad. Nauk, Ser. Biol., 2001, no. 5, pp. 607-610.
42. Pratt, K.R., Cote, H.C.F., and Chung, D.N., The Fibrin Polymerization Poket: Three-Dimensional Structure of a 30 KDa C-Termnal γ-Chain Fragment Complexed with the Peptide Gly-Pro-Arg-Pro, Proc. Natl. Acad. Sci. USA, 1997, vol. 94, pp. 7176-7181.
43. Ruggeri, Z., Mechanisms of Shear-Induced Platelet Adhesion and Aggregation, Thromb. Haemost, 1993, vol. 70, pp. 119-123.
44. Samonina, G., Lyapina, L., Kopylova, G., Pastorova, V., Jeliaznik, N., Zuykova, S., and Ashmarin, I.P., Maintenance of Gastric Mucosa Integrity Proline-Containing Peptides and Gelatin Preparation, Pathophysiol., 2000, vol. 7, pp. 69-73.
45. Samonina, G., Ashmarin, I., and Lyapina, L., Glyproline Peptide Family Review on Bioactivity and Possible Origins, Pathophysiol., 2002, vol. 8, no. 4, pp. 229-234.
46. Shennan, A.H., Review Antiplatelet Agents (Particularly Aspirin) Reduce the Incidence of Pre-eclampsia in Women at Risk, Evid. Based. Med., 2005, vol. 10, p. 49.
47. Shiffman, F.D., Patofiziologiya krovi (Blood Pathophysiology), Moscow: Binom, 2000.
48. Siljander, P.R., M., Hamaia S., Peachey A.R., Slatter D.A., Smethurst P.A., Ourrehand, W.H., Knight, C.G., and Farndale, R.W., Integrin Activation State Determines Selectivity for Novel Recognition Sites Fibrillar Collagen, J. Biol. Chem., 2004, vol. 279, no. 46, pp. 47763-47772.
49. 1 Integrin in Collagen, J. Biol. Chem., 1991, vol. 266, pp. 7363-7367.
50. 1, J. Biol. Chem., 2000, vol. 275, pp. 38981-38989.