Increased luteinizing hormone pulse frequency in obese oligomenorrheic girls with no evidence of hyperandrogenism

Fertility and Sterility

Volumn 85, Issue 4, 2006, Pages 1049-1056

  Yoo, Richard Y ^a   Dewan, Asheesh ^b   Basu, Reshmi ^c   Newfield, Ron ^b   Gottschalk, Michael ^b   Chang, R Jeffrey ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RADY CHILDREN'S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adolescence; Luteinizing hormone; Obesity; Oligomenorrhea; Pulse frequency

Indexed keywords

HYDROXYPROGESTERONE; LEUPRORELIN; LUTEINIZING HORMONE; STEROID HORMONE;

ADOLESCENT; ADULT; ANDROGEN BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPERANDROGENISM; OBESITY; OBSERVATIONAL STUDY; OLIGOMENORRHEA; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PULSE RATE; SCHOOL CHILD; SLEEP WAKING CYCLE; TERTIARY HEALTH CARE;

ADOLESCENT; CHILD; FEMALE; HUMANS; HYPERANDROGENISM; LUTEINIZING HORMONE; OBESITY; OLIGOMENORRHEA; POLYCYSTIC OVARY SYNDROME; PROSPECTIVE STUDIES; SLEEP STAGES;

EID: 33645390588     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2005.09.037     Document Type: Article

References (38)

1. S. Venturoli, E. Porcu, R. Fabbri, R. Paradisi, C. Magrini, L.F. Orsini Endocrine profiles and ovarian aspects in adolescent menstrual abnormalities C. Flamigni S. Venturoli J.R. Givens Adolescence in females 1985 Year Book Medical Publishers Chicago 239 250
2. R. Siegberg, C.G. Nilsson, U.H. Stenman, O. Widholm Endocrinologic features of oligomenorrheic adolescent girls Fertil Steril 46 1986 852 857
3. S. Venturoli, E. Porcu, R. Fabbri, R. Paradisi, S. Ruggeri, G.F. Belelli Menstrual irregularities in adolescents hormonal pattern and ovarian morphology Horm Res 24 1986 269 279
4. S. Venturoli, E. Porcu, R. Fabbri, R. Paradisi, L. Gammi, M. Passarini Ovarian mutlifollicularity, high LH and androgen plasma levels and anovulation are frequent and strongly linked in adolescent irregular cycles Acta Endocrinol (Copenh) 111 1986 368 373
5. M.H. van Hooff, F.J. Voorhorst, M.B. Kaptein, R.A. Hirasing, C. Koppenaal, J. Schoemaker Polycystic ovaries in adolescents and the relationship with menstrual cycle patterns, luteinizing hormone, androgens, and insulin Fertil Steril 74 2000 49 58
6. E. Porcu, S. Venturoli, O. Magrini Circadian variations of luteinizing hormone can have two different profiles in adolescent anovulation J Clin Endocrinol Metab 65 1987 488 493
7. D. Apter, T.L. Butzow, G.A. Laughlin, S.S. Yen Gonadotropin-releasing hormone pulse generator activity during pubertal transition in girls pulsatile and diurnal patterns of circulating gonadotropins J Clin Endocrinol Metab 76 1993 940 949
8. D. Apter, T. Butzow, G.A. Laughlin, S.S. Yen Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism relevance to the developmental phase of polycystic ovarian syndrome J Clin Endocrinol Metab 79 1994 119 125
9. S. Venturoli, E. Porcu, C. Flamigni Polycystic ovary syndrome Curr Opin Pediatr 1994 388 396
10. A.S. Rowland, D.D. Baird, S. Long, G. Wegienka, S.D. Harlow, M. Alavanja, D.P. Sandler Influence of medical conditions and lifestyle factors on the menstrual cycle Epidemiology 13 2002 668 674
11. A.J. Hartz, P.N. Barboriak, A. Wong, K.P. Katayama, A.A. Rimm The association of obesity with infertility and related menstrual abnormalities in women Int J Obes 3 1979 57 73
12. J.P. Symons, M.F. Sowers, S.D. Harlow Relationship of body composition measures and menstrual cycle length Ann Hum Biol 4 1997 107 116
13. J.W. Rich-Edwards, M.B. Goldman, W.C. Willett, D.J. Hunter, M.J. Stampfer, G.A. Colditz Adolescent body mass index and infertility caused by ovulatory disorder Am J Obstet Gynecol 171 1994 171 177
14. M.H. van Hooff, F.J. Voorhorst, M.B. Kaptein, R.A. Hirasing, C. Koppenaal, J. Schoemaker Predictive value of menstrual cycle pattern, body mass index, hormone levels and polycystic ovaries at age 15 years for oligo-amenorrhea at age 18 years Hum Reprod 19 2004 383 392
15. A. Must, P.F. Jacques, G.E. Dallal, C.J. Bajema, W.H. Dietz Long-term morbidity and mortality of overweight adolescents A follow-up of the Harvard Growth Study of 1922 to 1935 N Engl J Med 327 1992 1350 1355
16. The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 19 2004 41 47
17. Yoo RY, Sirlin CB, Gottschalk M, Chang RJ. Ovarian Imaging by magnetic resonance in obese adolescent girls with polycystic ovary syndrome: a pilot study. Fertil Steril. In press.
18. R.S. Mathur, L.O. Moody, S. Landgrebbe, H.O. Williamson Plasma androgens and sex hormone binding globulin in the evaluation of hirsute patients Fertil Steril 35 1981 29 37
19. J.D. Veldhuis, M.L. Johnson Cluster analysis a simple, versatile, and robust algorithm for endocrine pulse detection Am J Physiol 250 1986 E486 E493
20. C.R. McCartney, M.B. Gingrich, Y. Hu, W.S. Evans, J.C. Marshall Hypothalamic regulation of cyclic ovulation evidence that the increase in gonadotropin-releasing hormone pulse frequency during the follicular phase reflects the gradual loss of the restraining effects of progesterone J Clin Endocrinol Metab 87 2002 2194 2200
21. S. Venturoli, E. Porcu, R. Fabbri, C. Magrini, L. Gammi, R. Paradisi Longitudinal evaluation of the different gonadotropin pulsatile patterns in anovulatory cycles of young girls J Clin Endocrinol Metab 4 1992 836 841
22. A. Arroyo, G.A. Laughlin, A.J. Morales, S.S.C. Yen Inappropriate gonadotropin secretion in polycystic ovary syndrome influence of adiposity J Clin Endocrinol Metab 2 1997 3728 3733
23. A.E. Taylor, B. McCourt, K.A. Martin, E.J. Anderson, J.M. Adams, D. Schoenfeld Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome J Clin Endocrinol Metab 82 1997 2248 2256
24. K. Elkind-Hirsch, V. Ravnikar, I. Schiff, D. Tulchinsky, K.J. Ryan Determinations of endogenous immunoreactive luteinizing hormone-releasing hormone in human plasma J Clin Endocrinol Metab 54 1982 602 607
25. F.J. Karsch, D.L. Foster, E.L. Bittman, R.L. Goodman A role for estradiol in enhancing luteinizing hormone pulse frequency during the follicular phase of the estrous cycle of sheep Endocrinology 113 1983 1333 1339
26. J. Waldstreicher, N. Santoro, J. Hall, M. Filicori, W.F. Crowley Jr Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease indirect evidence for partial gonadotroph desensitization J Clin Endocrinol Metab 66 1988 165 172
27. E.Y. Adashi, C.E. Resnick, A. Vera, E.R. Hernandez In vivo regulation of granulosa cell type I insulin-like growth factor receptors evidence for an inhibitory role for the putative endogenous ligand(s) of the ovarian gonadotropin-releasing hormone receptor Endocrinology 128 1981 3130 3137
28. K. Patel, M.S. Coffler, M.H. Dahan, R.Y. Yoo, M.A. Lawson, P.J. Malcom, R.J. Chang Increased LH secretion in women with polycystic ovary syndrome is unaltered by prolonged insulin infusion J Clin Endocrinol Metab 88 2003 5456 5461
29. R.V. Mehta, K.S. Patel, M.S. Coffler, M.S. Dahan, R.Y. Yoo, J.S. Archer Luteinizing hormone secretion is not influenced by insulin infusion in women with polycystic ovary syndrome despite improved insulin sensitivity during pioglitazone treatment J Clin Endocrinol Metab 90 2004 2136 2141
30. C.A. Eagleson, M.B. Gingrich, C.L. Pastor, T.K. Arora, C.M. Burt, W.S. Evans Polycystic ovarian syndrome evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone J Clin Endocrinol Metab 85 2000 4047 4052
31. C.L. Pastor, M.L. Griffin-Korf, J.A. Aloi, W.S. Evans, J.C. Marshall Polycystic ovary syndrome evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone J Clin Endocrinol Metab 83 1998 582 590
32. T.L. Daniels, S.L. Berga Resistance of gonadotropin releasing hormone drive to sex steroid-induced suppression in hyperandrogenic anovulation J Clin Endocrinol Metab 82 1997 4179 4183
33. S. Chhabra, C.R. McCartney, R. Yoo, J. Chang, J.C. Marshall Progesterone inhibition of the hypothalamic GnRH pulse generator evidence for reduced effects in hyperandrogenemic adolescent girls J Clin Endocrinol Metab 90 2005 2810 2815
34. J.K. Lake, C. Power, T.J. Cole Women's reproductive health the role of body mass index in early and adult life Int J Obes Relat Metab Disord 21 1997 432 438
35. J. Argente, N. Caballo, V. Barrios, M.T. Munoz, J. Pozo, J.A. Chowen Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa effect of short- and long-term weight recuperation J Clin Endocrinol Metab 82 1997 2084 2092
36. J. Slowinska-Srzednicka, W. Zgliczynski, A. Makowska, W. Jeske, A. Brzezinska, P. Soszynski An abnormality of the growth hormone/insulin-like growth factor-I axis in women with polycystic ovary syndrome due to coexistent obesity J Clin Endocrinol Metab 74 1992 1432 1435
37. J. Laitinen, S. Taponen, H. Martikainen, A. Pouta, I. Millwood, A.L. Hartikainen Body size from birth to adulthood as a predictor of self-reported polycystic ovary syndrome symptoms Int J Obes Relat Metab Disord 27 2003 710 715
38. M. Filicori, N. Santoro, G.R. Merriam, W.F. Crowley Jr Characterization of the physiological pattern of episodic gonadotropin secretion throughout the human menstrual cycle J Clin Endocrinol Metab 62 1986 1136 1144